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Long-term efficacy and safety of aerosolized tobramycin 300 mg/4 ml in cystic fibrosis.
Mazurek H, Chiron R, Kucerova T, Geidel C, Bolbas K, Chuchalin A, Blanco-Aparicio M, Santoro D, Varoli G, Zibellini M, Cicirello HG, Antipkin YG. Mazurek H, et al. Pediatr Pulmonol. 2014 Nov;49(11):1076-89. doi: 10.1002/ppul.22989. Epub 2014 Jan 24. Pediatr Pulmonol. 2014. PMID: 24464974 Clinical Trial.
The primary endpoint of the core phase was to demonstrate the non-inferiority of TNS4 compared to TNS5 in terms of absolute change from baseline to week 4 in FEV(1) % predicted. The assessment of long-term safety was the primary purpose of the extension phase. Throughout a …
The primary endpoint of the core phase was to demonstrate the non-inferiority of TNS4 compared to TNS5 in terms of absolute change from base …
Liprotamase long-term safety and support of nutritional status in pancreatic-insufficient cystic fibrosis.
Borowitz D, Stevens C, Brettman LR, Campion M, Wilschanski M, Thompson H; Liprotamase 767 Study Group. Borowitz D, et al. J Pediatr Gastroenterol Nutr. 2012 Feb;54(2):248-57. doi: 10.1097/MPG.0b013e31823315d1. J Pediatr Gastroenterol Nutr. 2012. PMID: 22266487 Clinical Trial.
Liprotamase, a nonporcine, highly purified biotechnology-derived PERT, has demonstrated significant efficacy in fat and protein malabsorption in patients with EPI compared to placebo. This study of liprotamase is the first ever long-term trial of a PERT to evaluate safety …
Liprotamase, a nonporcine, highly purified biotechnology-derived PERT, has demonstrated significant efficacy in fat and protein malabsorptio …
[Effectiveness and safety of fluticasone propionate in therapy of children suffering from asthma. Part II. Safety aspects of therapy with fluticasone propionate in asthmatic children].
Bartkowiak-Emeryk M, Breborowicz A, Emeryk A, Kulus M, Kurzawa R, Lis G, Mazurek H, Niedziela M. Bartkowiak-Emeryk M, et al. Among authors: mazurek h. Pol Merkur Lekarski. 2004;17 Suppl 2:11-8. Pol Merkur Lekarski. 2004. PMID: 15688664 Review. Polish.
Recommended doses of FP given 1 to 2 years doesn't cause growth retardation. Long term studies on influence of drug on final height are needed. FP as other inhaled corticosteroids, may transiently alter bone metabolism. ...
Recommended doses of FP given 1 to 2 years doesn't cause growth retardation. Long term studies on influence of drug on final height a …
A 2-year-old girl with chronic crackles after respiratory syncytial virus infection: a case report.
Woicka-Kolejwa K, Mazurek H, Stelmach I. Woicka-Kolejwa K, et al. Among authors: mazurek h. J Med Case Rep. 2018 Sep 12;12(1):258. doi: 10.1186/s13256-018-1797-6. J Med Case Rep. 2018. PMID: 30205845 Free PMC article.
She was hospitalized eight times due to exacerbation of symptoms and prescribed systemic and inhaled steroids, short-acting beta2-mimetics, and antileukotriene. There was no short-term clinical improvement at that time between hospitalizations. ...
She was hospitalized eight times due to exacerbation of symptoms and prescribed systemic and inhaled steroids, short-acting beta2-mimetics, …
A formulation of aerosolized tobramycin (Bramitob) in the treatment of patients with cystic fibrosis and Pseudomonas aeruginosa infection: a double-blind, placebo-controlled, multicenter study.
Chuchalin A, Csiszér E, Gyurkovics K, Bartnicka MT, Sands D, Kapranov N, Varoli G, Monici Preti PA, Mazurek H. Chuchalin A, et al. Among authors: mazurek h. Paediatr Drugs. 2007;9 Suppl 1:21-31. doi: 10.2165/00148581-200709001-00004. Paediatr Drugs. 2007. PMID: 17536872 Clinical Trial.
The proportion of patients with drug-related adverse events was 15% in both treatment groups. CONCLUSIONS: Long-term, intermittent administration of this aerosolized tobramycin formulation (300mg/4mL) in CF patients with P. aeruginosa chronic infection significantly improv …
The proportion of patients with drug-related adverse events was 15% in both treatment groups. CONCLUSIONS: Long-term, intermittent ad …
[Is prediction of the allergic march possible on the basis of nasal cytology?].
Nowacki Z, Neuberg J, Strzałka K, Szczepanik M, Szczepanik R, Mazurek H. Nowacki Z, et al. Among authors: mazurek h. Pneumonol Alergol Pol. 2010;78(4):263-70. Pneumonol Alergol Pol. 2010. PMID: 20665446 Free article. Polish.
INTRODUCTION: The term allergic march has been used to describe natural evolution of the atopic disease in children, accompanied by the change in organ manifestation with time. ...
INTRODUCTION: The term allergic march has been used to describe natural evolution of the atopic disease in children, accompanied by t …