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Mitochondria and neuroprotection in stroke: Cationic arginine-rich peptides (CARPs) as a novel class of mitochondria-targeted neuroprotective therapeutics.
MacDougall G, Anderton RS, Mastaglia FL, Knuckey NW, Meloni BP. MacDougall G, et al. Among authors: mastaglia fl. Neurobiol Dis. 2019 Jan;121:17-33. doi: 10.1016/j.nbd.2018.09.010. Epub 2018 Sep 13. Neurobiol Dis. 2019. PMID: 30218759 Review.
Stroke is the second leading cause of death globally and represents a major cause of devastating long-term disability. Despite sustained efforts to develop clinically effective neuroprotective therapies, presently there is no clinically available neuroprotective agent for …
Stroke is the second leading cause of death globally and represents a major cause of devastating long-term disability. Despite sustai …
Natural history of benign multiple sclerosis: Clinical and HLA correlates in a Western Australian cohort.
Fabis-Pedrini MJ, James I, Seewann A, Yau WY, van de Bovenkamp AA, Sanders FRK, Qiu W, Burton J, Mastaglia FL, Carroll WM, Kermode AG. Fabis-Pedrini MJ, et al. Among authors: mastaglia fl. J Neurol Sci. 2018 May 15;388:12-18. doi: 10.1016/j.jns.2018.02.036. Epub 2018 Feb 22. J Neurol Sci. 2018. PMID: 29627005
BACKGROUND: Benign multiple sclerosis (BMS) is a controversial term that has been used for MS patients with minimal disability decades after disease onset. ...
BACKGROUND: Benign multiple sclerosis (BMS) is a controversial term that has been used for MS patients with minimal disability decade …
Breakdown in central motor control can be attenuated by motor practice and neuro-modulation of the primary motor cortex.
Teo WP, Rodrigues JP, Mastaglia FL, Thickbroom GW. Teo WP, et al. Among authors: mastaglia fl. Neuroscience. 2012 Sep 18;220:11-8. doi: 10.1016/j.neuroscience.2012.06.048. Epub 2012 Jun 28. Neuroscience. 2012. PMID: 22750241
The results implicate central motor processes in the performance and sustainability of the MVR task, and indicate that MVR kinematics can improve with short-term training and with non-invasive neuro-modulation....
The results implicate central motor processes in the performance and sustainability of the MVR task, and indicate that MVR kinematics can im …
Long-term changes in motor cortical organisation after recovery from subcortical stroke.
Byrnes ML, Thickbroom GW, Phillips BA, Mastaglia FL. Byrnes ML, et al. Among authors: mastaglia fl. Brain Res. 2001 Jan 19;889(1-2):278-87. doi: 10.1016/s0006-8993(00)03089-4. Brain Res. 2001. PMID: 11166720 Clinical Trial.
The present study has investigated the long-term changes in the organisation of the corticomotor projection to the hand in a group of subjects who had sustained a subcortical hemispheric stroke up to 15 years previously and had subsequently recovered normal or near-normal …
The present study has investigated the long-term changes in the organisation of the corticomotor projection to the hand in a group of …
Exercise therapy in patients with myopathy.
Phillips BA, Mastaglia FL. Phillips BA, et al. Among authors: mastaglia fl. Curr Opin Neurol. 2000 Oct;13(5):547-52. doi: 10.1097/00019052-200010000-00007. Curr Opin Neurol. 2000. PMID: 11073361 Review.
Strength-training programmes, incorporating isometric, isotonic or isokinetic exercise, have been shown to improve muscle strength in the short term, without evidence of increased muscle damage using biochemical markers. ...
Strength-training programmes, incorporating isometric, isotonic or isokinetic exercise, have been shown to improve muscle strength in the sh …
Functional reorganisation of the corticomotor projection to the hand in skilled racquet players.
Pearce AJ, Thickbroom GW, Byrnes ML, Mastaglia FL. Pearce AJ, et al. Among authors: mastaglia fl. Exp Brain Res. 2000 Jan;130(2):238-43. doi: 10.1007/s002219900236. Exp Brain Res. 2000. PMID: 10672477 Free article.
While it is known that relatively rapid changes in functional representation may occur in the human sensorimotor cortex in short-term motor-learning studies, there have been few studies of changes in organisation of the corticomotor system associated with the long-term …
While it is known that relatively rapid changes in functional representation may occur in the human sensorimotor cortex in short-term …
Treatment of inflammatory myopathies.
Mastaglia FL, Laing BA, Zilko P. Mastaglia FL, et al. Baillieres Clin Neurol. 1993 Nov;2(3):717-40. Baillieres Clin Neurol. 1993. PMID: 8156149 Review.
The same applies to cyclosporin, which has a more selective action on T cells, and which has been reported to be effective in resistant cases of adult and juvenile polymyositis and dermatomyositis. In the longer term, the development of more specific forms of immunotherapy …
The same applies to cyclosporin, which has a more selective action on T cells, and which has been reported to be effective in resistant case …
Guillain-Barré syndrome and pemphigus foliaceus associated with D-penicillamine therapy.
Knezevic W, Mastaglia FL, Quintner J, Zilko PJ. Knezevic W, et al. Among authors: mastaglia fl. Aust N Z J Med. 1984 Feb;14(1):50-2. doi: 10.1111/j.1445-5994.1984.tb03586.x. Aust N Z J Med. 1984. PMID: 6590007
The Guillain-Barre syndrome and pemphigus foliaceus occurred simultaneously in a patient on long-term treatment with D-penicillamine. It is proposed that both conditions may have developed as a result of a disturbance of immunoregulation caused by D-penicillamine....
The Guillain-Barre syndrome and pemphigus foliaceus occurred simultaneously in a patient on long-term treatment with D-penicillamine. …
Choline chloride in the treatment of cerebellar and spinocerebellar ataxia.
Livingstone IR, Mastaglia FL, Pennington RJ, Skilbeck C. Livingstone IR, et al. Among authors: mastaglia fl. J Neurol Sci. 1981 May;50(2):161-74. doi: 10.1016/0022-510x(81)90162-3. J Neurol Sci. 1981. PMID: 7229661
The use of orally administered choline chloride in the treatment of cerebellar and spinocerebellar ataxia was investigated by a short-term double-blind crossover trial in 20 patients with ataxia. These patients, who include 7 with Friedreich's ataxia, 7 with mixed spinocer …
The use of orally administered choline chloride in the treatment of cerebellar and spinocerebellar ataxia was investigated by a short-ter …