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Does lobar or size-reduced lung transplantation offer satisfactory early and late outcomes?
Santos Silva J, Olland A, Massard G, Falcoz PE. Santos Silva J, et al. Among authors: massard g. Interact Cardiovasc Thorac Surg. 2020 Jul 1;31(1):93-97. doi: 10.1093/icvts/ivaa051. Interact Cardiovasc Thorac Surg. 2020. PMID: 32588059 Free PMC article. Review.
All studies reported survival rates of LLTx and most compared it with classical LTx. No statistical differences were reported in medium term and long term. Two of the studies reported a higher incidence of postoperative complications, such as the need for cardiopulm …
All studies reported survival rates of LLTx and most compared it with classical LTx. No statistical differences were reported in medium t …
Impact of donor, recipient and matching on survival after high emergency lung transplantation in France.
Roussel A, Sage E, Massard G, Thomas PA, Castier Y, Fadel E, Le Pimpec-Barthes F, Maury JM, Jougon J, Lacoste P, Claustre J, Dahan M, Pirvu A, Tissot A, Thumerel M, Drevet G, Pricopi C, Le Pavec J, Mal H, D'Journo XB, Kessler R, Roux A, Dorent R, Thabut G, Mordant P; French Groups of Lung Transplantation. Roussel A, et al. Among authors: massard g. Eur Respir J. 2019 Nov 7;54(5):1900096. doi: 10.1183/13993003.00096-2019. Print 2019 Nov. Eur Respir J. 2019. PMID: 31601709 Free article.
HELT was associated with a hazard ratio for death of 1.41 (95% CI 1.22-1.64; p<0.0001) in univariate analysis, decreasing to 1.32 (95% CI 1.10-1.60) after inclusion of recipient characteristics in a multivariate model. A donor score computed to predict long-term surviva …
HELT was associated with a hazard ratio for death of 1.41 (95% CI 1.22-1.64; p<0.0001) in univariate analysis, decreasing to 1.32 (95% CI …
In lung transplantation, are pulmonary grafts from donors deceased from hanging as suitable as grafts from donors deceased from other causes?
Santos Silva J, Olland A, Massard G, Falcoz PE. Santos Silva J, et al. Among authors: massard g. Interact Cardiovasc Thorac Surg. 2020 Jan 1;30(1):30-32. doi: 10.1093/icvts/ivz218. Interact Cardiovasc Thorac Surg. 2020. PMID: 31511853
No differences in the rates of post-transplantation pulmonary graft dysfunction and long-term overall survival were reported. Although the cohort of donors deceased from hanging is small, we conclude that these donors are an important contribution to the donor pool. ...
No differences in the rates of post-transplantation pulmonary graft dysfunction and long-term overall survival were reported. Althoug …
Blood CD9+ B cell, a biomarker of bronchiolitis obliterans syndrome after lung transplantation.
Brosseau C, Danger R, Durand M, Durand E, Foureau A, Lacoste P, Tissot A, Roux A, Reynaud-Gaubert M, Kessler R, Mussot S, Dromer C, Brugière O, Mornex JF, Guillemain R, Claustre J, Magnan A, Brouard S; COLT and SysCLAD Consortia. Brosseau C, et al. Am J Transplant. 2019 Nov;19(11):3162-3175. doi: 10.1111/ajt.15532. Epub 2019 Aug 21. Am J Transplant. 2019. PMID: 31305014 Free article.
Bronchiolitis obliterans syndrome is the main limitation for long-term survival after lung transplantation. Some specific B cell populations are associated with long-term graft acceptance. ...CD9-expressing B cells appear as a contributor to a favorable environment …
Bronchiolitis obliterans syndrome is the main limitation for long-term survival after lung transplantation. Some specific B cell popu …
Stereotactic body radiation therapy for stage I non-small cell lung carcinomas: Moderate hypofractionation optimizes outcome.
Menoux I, Antoni D, Truntzer P, Keller A, Massard G, Noël G. Menoux I, et al. Among authors: massard g. Lung Cancer. 2018 Dec;126:201-207. doi: 10.1016/j.lungcan.2018.11.013. Epub 2018 Nov 16. Lung Cancer. 2018. PMID: 30527188
MATERIALS AND METHODS: This study is a retrospective analysis of 90 patients who underwent SBRT for a stage I NSCLC between 2010 and 2015. Its purpose is to describe its effectiveness in term of overall survival (OS), specific survival (SS), local control (LC), regional co …
MATERIALS AND METHODS: This study is a retrospective analysis of 90 patients who underwent SBRT for a stage I NSCLC between 2010 and 2015. I …
Normothermic ex-vivo preservation with the portable Organ Care System Lung device for bilateral lung transplantation (INSPIRE): a randomised, open-label, non-inferiority, phase 3 study.
Warnecke G, Van Raemdonck D, Smith MA, Massard G, Kukreja J, Rea F, Loor G, De Robertis F, Nagendran J, Dhital KK, Moradiellos Díez FJ, Knosalla C, Bermudez CA, Tsui S, McCurry K, Wang IW, Deuse T, Lesèche G, Thomas P, Tudorache I, Kühn C, Avsar M, Wiegmann B, Sommer W, Neyrinck A, Schiavon M, Calabrese F, Santelmo N, Olland A, Falcoz PE, Simon AR, Varela A, Madsen JC, Hertz M, Haverich A, Ardehali A. Warnecke G, et al. Among authors: massard g. Lancet Respir Med. 2018 May;6(5):357-367. doi: 10.1016/S2213-2600(18)30136-X. Epub 2018 Apr 9. Lancet Respir Med. 2018. PMID: 29650408 Clinical Trial.
INTERPRETATION: The INSPIRE trial met its primary effectiveness and safety endpoints. Although no short-term survival benefit was reported, further research is needed to see whether the reduced incidence of PGD3 within 72 h of a transplant might translate into earlier reco …
INTERPRETATION: The INSPIRE trial met its primary effectiveness and safety endpoints. Although no short-term survival benefit was rep …
Blood Gene Expression Predicts Bronchiolitis Obliterans Syndrome.
Danger R, Royer PJ, Reboulleau D, Durand E, Loy J, Tissot A, Lacoste P, Roux A, Reynaud-Gaubert M, Gomez C, Kessler R, Mussot S, Dromer C, Brugière O, Mornex JF, Guillemain R, Dahan M, Knoop C, Botturi K, Foureau A, Pison C, Koutsokera A, Nicod LP, Brouard S, Magnan A; COLT and SysCLAD Consortia. Danger R, et al. Front Immunol. 2018 Jan 11;8:1841. doi: 10.3389/fimmu.2017.01841. eCollection 2017. Front Immunol. 2018. PMID: 29375549 Free PMC article.
Bronchiolitis obliterans syndrome (BOS), the main manifestation of chronic lung allograft dysfunction, leads to poor long-term survival after lung transplantation. Identifying predictors of BOS is essential to prevent the progression of dysfunction before irreversible dama …
Bronchiolitis obliterans syndrome (BOS), the main manifestation of chronic lung allograft dysfunction, leads to poor long-term surviv …
Airway microbiota signals anabolic and catabolic remodeling in the transplanted lung.
Mouraux S, Bernasconi E, Pattaroni C, Koutsokera A, Aubert JD, Claustre J, Pison C, Royer PJ, Magnan A, Kessler R, Benden C, Soccal PM, Marsland BJ, Nicod LP; SysCLAD Consortium. Mouraux S, et al. J Allergy Clin Immunol. 2018 Feb;141(2):718-729.e7. doi: 10.1016/j.jaci.2017.06.022. Epub 2017 Jul 18. J Allergy Clin Immunol. 2018. PMID: 28729000 Free PMC article. Clinical Trial.
BACKGROUND: Homeostatic turnover of the extracellular matrix conditions the structure and function of the healthy lung. In lung transplantation, long-term management remains limited by chronic lung allograft dysfunction, an umbrella term used for a heterogeneous ent …
BACKGROUND: Homeostatic turnover of the extracellular matrix conditions the structure and function of the healthy lung. In lung transplantat …
Early and Late Atrial Arrhythmias After Lung Transplantation　- Incidence, Predictive Factors and Impact on Mortality.
Jesel L, Barraud J, Lim HS, Marzak H, Messas N, Hirschi S, Santelmo N, Olland A, Falcoz PE, Massard G, Kindo M, Ohlmann P, Chauvin M, Morel O, Kessler R. Jesel L, et al. Among authors: massard g. Circ J. 2017 Apr 25;81(5):660-667. doi: 10.1253/circj.CJ-16-0892. Epub 2017 Feb 15. Circ J. 2017. PMID: 28202855 Free article.
Pretransplant systolic pulmonary arterial pressure (PTsPAP) was the only independent predictive factor of late AA (OR 1.028; CI [1.001-1.056]; P=0.04). Double LT was associated with long-term freedom from atrial fibrillation (AF) but not from atrial flutter (AFL). ...
Pretransplant systolic pulmonary arterial pressure (PTsPAP) was the only independent predictive factor of late AA (OR 1.028; CI [1.001-1.056 …
T Cells Promote Bronchial Epithelial Cell Secretion of Matrix Metalloproteinase-9 via a C-C Chemokine Receptor Type 2 Pathway: Implications for Chronic Lung Allograft Dysfunction.
Pain M, Royer PJ, Loy J, Girardeau A, Tissot A, Lacoste P, Roux A, Reynaud-Gaubert M, Kessler R, Mussot S, Dromer C, Brugière O, Mornex JF, Guillemain R, Dahan M, Knoop C, Botturi K, Pison C, Danger R, Brouard S, Magnan A; COLT Consortium. Pain M, et al. Am J Transplant. 2017 Jun;17(6):1502-1514. doi: 10.1111/ajt.14166. Epub 2017 Jan 23. Am J Transplant. 2017. PMID: 27982503 Free article.
Chronic lung allograft dysfunction (CLAD) is the major limitation of long-term survival after lung transplantation. CLAD manifests as bronchiolitis obliterans syndrome (BOS) or restrictive allograft syndrome (RAS). ...
Chronic lung allograft dysfunction (CLAD) is the major limitation of long-term survival after lung transplantation. CLAD manifests as …
39 results