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Acute Toxicity Assessment of Orally Administered Microplastic Particles in Adult Male Wistar Rats.
Guševac Stojanović I, Drakulić D, Todorović A, Martinović J, Filipović N, Stojanović Z. Guševac Stojanović I, et al. Among authors: martinovic j. Toxics. 2024 Feb 22;12(3):167. doi: 10.3390/toxics12030167. Toxics. 2024. PMID: 38535900 Free PMC article.
To investigate MPs' potential acute toxicity, including their impact on general health status (victual consumption, sensorimotor deficits, and clinical toxicity signs) and serum biochemical parameters (markers of organ/tissue function and oxidative stress indicators), we administ …
To investigate MPs' potential acute toxicity, including their impact on general health status (victual consumption, sensorimotor deficits, a …
Prolonged Zaleplon Treatment Increases the Expression of Proteins Involved in GABAergic and Glutamatergic Signaling in the Rat Hippocampus.
Martinovic J, Samardzic J, Zaric Kontic M, Ivkovic S, Dacic S, Major T, Radosavljevic M, Svob Strac D. Martinovic J, et al. Brain Sci. 2023 Dec 12;13(12):1707. doi: 10.3390/brainsci13121707. Brain Sci. 2023. PMID: 38137155 Free PMC article.
Zaleplon is a positive allosteric modulator of the gamma-aminobutyric acid (GABA)(A) receptor approved for the short-term treatment of insomnia. Previous publications on zaleplon have not addressed the proteins involved in its mechanism of action but have mostly referred t …
Zaleplon is a positive allosteric modulator of the gamma-aminobutyric acid (GABA)(A) receptor approved for the short-term treatment o …
Prolonged Alprazolam Treatment Alters Components of Glutamatergic Neurotransmission in the Hippocampus of Male Wistar Rats-The Neuroadaptive Changes following Long-Term Benzodiazepine (Mis)Use.
Zaric Kontic M, Dragic M, Martinovic J, Mihajlovic K, Brkic Z, Mitrovic N, Grkovic I. Zaric Kontic M, et al. Among authors: martinovic j. Pharmaceuticals (Basel). 2023 Feb 21;16(3):331. doi: 10.3390/ph16030331. Pharmaceuticals (Basel). 2023. PMID: 36986431 Free PMC article.
Alprazolam (ALP), a benzodiazepine (BDZ) used to treat anxiety, panic, and sleep disorders, is one of the most prescribed psychotropic drugs worldwide. The side effects associated with long-term (mis)use of ALP have become a major challenge in pharmacotherapy, emphasizing …
Alprazolam (ALP), a benzodiazepine (BDZ) used to treat anxiety, panic, and sleep disorders, is one of the most prescribed psychotropic drugs …
Safety and efficacy of once-daily risdiplam in type 2 and non-ambulant type 3 spinal muscular atrophy (SUNFISH part 2): a phase 3, double-blind, randomised, placebo-controlled trial.
Mercuri E, Deconinck N, Mazzone ES, Nascimento A, Oskoui M, Saito K, Vuillerot C, Baranello G, Boespflug-Tanguy O, Goemans N, Kirschner J, Kostera-Pruszczyk A, Servais L, Gerber M, Gorni K, Khwaja O, Kletzl H, Scalco RS, Staunton H, Yeung WY, Martin C, Fontoura P, Day JW; SUNFISH Study Group. Mercuri E, et al. Lancet Neurol. 2022 Jan;21(1):42-52. doi: 10.1016/S1474-4422(21)00367-7. Lancet Neurol. 2022. PMID: 34942136
SUNFISH part 2 is ongoing and will provide additional evidence regarding the long-term safety and efficacy of risdiplam. FUNDING: F Hoffmann-La Roche....
SUNFISH part 2 is ongoing and will provide additional evidence regarding the long-term safety and efficacy of risdiplam. FUNDING: F H …
Preserved efficiency of sickle cell disease placentas despite altered morphology and function.
Cordier AG, Bouvier AS, Vibert F, Martinovic J, Couturier-Tarrade A, Lai-Kuen R, Curis E, Fournier T, Benachi A, Peoc'H K, Gil S. Cordier AG, et al. Among authors: martinovic j. Placenta. 2020 Oct;100:81-88. doi: 10.1016/j.placenta.2020.08.008. Epub 2020 Aug 19. Placenta. 2020. PMID: 32871493
METHODS: Clinical records, placental and blood samples were collected at term delivery for 21 pregnant patients with SCD and 19 HbAA pregnant controls with adapted to gestational age birth weight newborns. ...
METHODS: Clinical records, placental and blood samples were collected at term delivery for 21 pregnant patients with SCD and 19 HbAA …
Increased TGF-β: a drawback of tracheal occlusion in human and experimental congenital diaphragmatic hernia?
Vuckovic A, Herber-Jonat S, Flemmer AW, Ruehl IM, Votino C, Segers V, Benachi A, Martinovic J, Nowakowska D, Dzieniecka M, Jani JC. Vuckovic A, et al. Among authors: martinovic j. Am J Physiol Lung Cell Mol Physiol. 2016 Feb 15;310(4):L311-27. doi: 10.1152/ajplung.00122.2015. Epub 2015 Dec 4. Am J Physiol Lung Cell Mol Physiol. 2016. PMID: 26637634 Free article.
Pulmonary expression of TGF-beta signaling components, downstream effectors, and extracellular matrix targets were evaluated in CDH neonates who died between birth and the first few weeks of life after prenatal conservative management or TO, and in rabbit pups that were pr …
Pulmonary expression of TGF-beta signaling components, downstream effectors, and extracellular matrix targets were evaluated in CDH neonates …
Hematological, oxidative stress, and immune status profiling in elite combat sport athletes.
Dopsaj V, Martinovic J, Dopsaj M, Kasum G, Kotur-Stevuljevic J, Koropanovski N. Dopsaj V, et al. Among authors: martinovic j. J Strength Cond Res. 2013 Dec;27(12):3506-14. doi: 10.1519/JSC.0b013e31828ddeea. J Strength Cond Res. 2013. PMID: 24270459
The low pro-oxidant-antioxidant balance and high SOD activity in wrestlers could be associated with the long-term impact of wrestling as a type of strenuous exercise....
The low pro-oxidant-antioxidant balance and high SOD activity in wrestlers could be associated with the long-term impact of wrestling …
Asphyxiating thoracic dysplasia: clinical and molecular review of 39 families.
Baujat G, Huber C, El Hokayem J, Caumes R, Do Ngoc Thanh C, David A, Delezoide AL, Dieux-Coeslier A, Estournet B, Francannet C, Kayirangwa H, Lacaille F, Le Bourgeois M, Martinovic J, Salomon R, Sigaudy S, Malan V, Munnich A, Le Merrer M, Le Quan Sang KH, Cormier-Daire V. Baujat G, et al. Among authors: martinovic j. J Med Genet. 2013 Feb;50(2):91-8. doi: 10.1136/jmedgenet-2012-101282. J Med Genet. 2013. PMID: 23339108
The clinical and molecular heterogeneity leads to difficulties in the evaluation of the long-term prognosis. METHODS: We investigated 53 ATD cases (23 living cases and 30 fetuses) from 39 families. ...The presence of only one mutation in six families and the exclusion of t …
The clinical and molecular heterogeneity leads to difficulties in the evaluation of the long-term prognosis. METHODS: We investigated …
FGF9 and FGF20 maintain the stemness of nephron progenitors in mice and man.
Barak H, Huh SH, Chen S, Jeanpierre C, Martinovic J, Parisot M, Bole-Feysot C, Nitschké P, Salomon R, Antignac C, Ornitz DM, Kopan R. Barak H, et al. Among authors: martinovic j. Dev Cell. 2012 Jun 12;22(6):1191-207. doi: 10.1016/j.devcel.2012.04.018. Dev Cell. 2012. PMID: 22698282 Free PMC article.
These findings identify a long-sought-after critical component of the nephron stem cell niche and hold promise for long-term culture and utilization of these progenitors in vitro....
These findings identify a long-sought-after critical component of the nephron stem cell niche and hold promise for long-term culture …
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