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Brodalumab: 5-Year US Pharmacovigilance Report.
Lebwohl MG, Koo JY, Armstrong AW, Strober BE, Martin GM, Rawnsley NN, Goehring EL Jr, Jacobson AA. Lebwohl MG, et al. Among authors: martin gm. Dermatol Ther (Heidelb). 2024 May 9. doi: 10.1007/s13555-024-01162-8. Online ahead of print. Dermatol Ther (Heidelb). 2024. PMID: 38724839
CONCLUSION: Five-year pharmacovigilance data are consistent with the established safety profile reported in long-term clinical trials and previous pharmacovigilance reports, with no new safety signals. ...Taken together, these data are consistent with safety findings from …
CONCLUSION: Five-year pharmacovigilance data are consistent with the established safety profile reported in long-term clinical trials …
Cost-effectiveness of multicomponent interventions in type 2 diabetes mellitus in a cluster randomised controlled trial: the INDICA study.
García-Pérez L, Ramallo-Fariña Y, Vallejo-Torres L, Rodríguez-Rodríguez L, González-Pacheco H, Santos-Hernández B, García-Bello MA, Wägner AM, Carmona M, Serrano-Aguilar PG; INDICA team. García-Pérez L, et al. BMJ Open. 2022 Apr 8;12(4):e058049. doi: 10.1136/bmjopen-2021-058049. BMJ Open. 2022. PMID: 35396305 Free PMC article. Clinical Trial.
CONCLUSIONS: The INDICA intervention designed for patients with T2DM and families is likely to be cost-effective from the public healthcare perspective. A cost-effectiveness model should explore this in the long term. TRIAL REGISTRATION NUMBER: NCT01657227....
CONCLUSIONS: The INDICA intervention designed for patients with T2DM and families is likely to be cost-effective from the public healthcare …
Patient-reported outcome measures for knowledge transfer and behaviour modification interventions in type 2 diabetes-the INDICA study: a multiarm cluster randomised controlled trial.
Ramallo-Fariña Y, Rivero-Santana A, García-Pérez L, García-Bello MA, Wägner AM, Gonzalez-Pacheco H, Rodríguez-Rodríguez L, Kaiser-Girardot S, Monzón-Monzón G, Guerra-Marrero C, Daranas-Aguilar C, Roldán-Ruano M, Carmona M, Serrano-Aguilar PG; INDICA Team. Ramallo-Fariña Y, et al. BMJ Open. 2021 Dec 15;11(12):e050804. doi: 10.1136/bmjopen-2021-050804. BMJ Open. 2021. PMID: 34911711 Free PMC article. Clinical Trial.
OBJECTIVE: This study assesses the effectiveness of different interventions of knowledge transfer and behaviour modification to improve type 2 diabetes mellitus patients' (T2DM) reported outcomes measures (PROMs) in the long-term. Design: open, community-based pragmatic, m …
OBJECTIVE: This study assesses the effectiveness of different interventions of knowledge transfer and behaviour modification to improve type …
Testing a global standard for quantifying species recovery and assessing conservation impact.
Grace MK, Akçakaya HR, Bennett EL, Brooks TM, Heath A, Hedges S, Hilton-Taylor C, Hoffmann M, Hochkirch A, Jenkins R, Keith DA, Long B, Mallon DP, Meijaard E, Milner-Gulland EJ, Rodriguez JP, Stephenson PJ, Stuart SN, Young RP, Acebes P, Alfaro-Shigueto J, Alvarez-Clare S, Andriantsimanarilafy RR, Arbetman M, Azat C, Bacchetta G, Badola R, Barcelos LMD, Barreiros JP, Basak S, Berger DJ, Bhattacharyya S, Bino G, Borges PAV, Boughton RK, Brockmann HJ, Buckley HL, Burfield IJ, Burton J, Camacho-Badani T, Cano-Alonso LS, Carmichael RH, Carrero C, Carroll JP, Catsadorakis G, Chapple DG, Chapron G, Chowdhury GW, Claassens L, Cogoni D, Constantine R, Craig CA, Cunningham AA, Dahal N, Daltry JC, Das GC, Dasgupta N, Davey A, Davies K, Develey P, Elangovan V, Fairclough D, Febbraro MD, Fenu G, Fernandes FM, Fernandez EP, Finucci B, Földesi R, Foley CM, Ford M, Forstner MRJ, García N, Garcia-Sandoval R, Gardner PC, Garibay-Orijel R, Gatan-Balbas M, Gauto I, Ghazi MGU, Godfrey SS, Gollock M, González BA, Grant TD, Gray T, Gregory AJ, van Grunsven RHA, Gryzenhout M, Guernsey NC, Gupta G, Hagen C, Hagen CA, Hall MB, Hallerman E, Hare K, Hart T, Hartdegen R, Harvey-Brown Y, Hatfield R, Hawke T, … See abstract for full author list ➔ Grace MK, et al. Among authors: martin gm. Conserv Biol. 2021 Dec;35(6):1833-1849. doi: 10.1111/cobi.13756. Epub 2021 Jul 21. Conserv Biol. 2021. PMID: 34289517
Based on our results, we devised an updated assessment framework that introduces the option of using a dynamic baseline to assess future impacts of conservation over the short term to avoid misleading results which were generated in a small number of cases, and redefines s …
Based on our results, we devised an updated assessment framework that introduces the option of using a dynamic baseline to assess future imp …
Single injection of rapamycin blocks post-food restriction hyperphagia and body-weight regain in rats.
Kenny TE, Hebert M, MacCallum P, Whiteman J, Martin GM, Blundell J. Kenny TE, et al. Among authors: martin gm. Behav Neurosci. 2019 Feb;133(1):98-109. doi: 10.1037/bne0000287. Behav Neurosci. 2019. PMID: 30688487
Given the increasing prevalence of and severity of complications associated with obesity, there is great need for treatments resulting in prolonged weight loss. Long-term maintenance of weight loss requires sustained changes in food-intake and energy-expenditure strategies …
Given the increasing prevalence of and severity of complications associated with obesity, there is great need for treatments resulting in pr …
Locus Coeruleus Optogenetic Light Activation Induces Long-Term Potentiation of Perforant Path Population Spike Amplitude in Rat Dentate Gyrus.
Quinlan MAL, Strong VM, Skinner DM, Martin GM, Harley CW, Walling SG. Quinlan MAL, et al. Among authors: martin gm. Front Syst Neurosci. 2019 Jan 9;12:67. doi: 10.3389/fnsys.2018.00067. eCollection 2018. Front Syst Neurosci. 2019. PMID: 30687027 Free PMC article.
Norepinephrine (NE) in dentate gyrus (DG) produces NE-dependent long-term potentiation (NE-LTP) of the perforant path-evoked potential population spike both in vitro and in vivo. ...The LTP of PP responses induced by optogenetic LC activation is consistent with the role of …
Norepinephrine (NE) in dentate gyrus (DG) produces NE-dependent long-term potentiation (NE-LTP) of the perforant path-evoked potentia …
Enhancing Reuse of Data and Biological Material in Medical Research: From FAIR to FAIR-Health.
Holub P, Kohlmayer F, Prasser F, Mayrhofer MT, Schlünder I, Martin GM, Casati S, Koumakis L, Wutte A, Kozera Ł, Strapagiel D, Anton G, Zanetti G, Sezerman OU, Mendy M, Valík D, Lavitrano M, Dagher G, Zatloukal K, van Ommen GB, Litton JE. Holub P, et al. Among authors: martin gm. Biopreserv Biobank. 2018 Apr;16(2):97-105. doi: 10.1089/bio.2017.0110. Epub 2018 Jan 23. Biopreserv Biobank. 2018. PMID: 29359962 Free PMC article. Review.
This approach would facilitate access to complete provenance information, which is a prerequisite for reproducibility and meaningful integration of the data. A unified view also allows for optimization of long-term storage strategies, as demonstrated in the case of biobank …
This approach would facilitate access to complete provenance information, which is a prerequisite for reproducibility and meaningful integra …
The effects of prolonged administration of norepinephrine reuptake inhibitors on long-term potentiation in dentate gyrus, and on tests of spatial and object recognition memory in rats.
Walling SG, Milway JS, Ingram M, Lau C, Morrison G, Martin GM. Walling SG, et al. Among authors: martin gm. Neurobiol Learn Mem. 2016 Feb;128:92-102. doi: 10.1016/j.nlm.2015.12.013. Epub 2016 Jan 7. Neurobiol Learn Mem. 2016. PMID: 26774023
Short- (4-h) and long-term (24-h) spatial memory was tested in separate rats administered 0 or 7.5mg/kg/day DMI (25-30 days) using a two-trial spatial memory test. ...Animals in the high-dose NTP (20mg/kg/day) group were impaired at both short- and long-term interva …
Short- (4-h) and long-term (24-h) spatial memory was tested in separate rats administered 0 or 7.5mg/kg/day DMI (25-30 days) using a …
Rapamycin decreases DNA damage accumulation and enhances cell growth of WRN-deficient human fibroblasts.
Saha B, Cypro A, Martin GM, Oshima J. Saha B, et al. Among authors: martin gm. Aging Cell. 2014 Jun;13(3):573-5. doi: 10.1111/acel.12190. Epub 2014 Feb 5. Aging Cell. 2014. PMID: 24308646 Free PMC article.
We observed increased autophagy in WRN knockdown cells; this was further increased by short-term rapamycin treatment. Long-term rapamycin treatment resulted in improved growth rate, reduced accumulation of DNA damage foci and improved nuclear morphology; autophagy m …
We observed increased autophagy in WRN knockdown cells; this was further increased by short-term rapamycin treatment. Long-term …
24 results