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Post-treatment and spontaneous HIV control.
Martin GE, Frater J. Martin GE, et al. Curr Opin HIV AIDS. 2018 Sep;13(5):402-407. doi: 10.1097/COH.0000000000000488. Curr Opin HIV AIDS. 2018. PMID: 29878914 Review.
We explore options around deriving a consensus on how to define different forms of control and the longer term utility of achieving remission. SUMMARY: Post-treatment control and remission following treatment interruption are becoming increasingly common measures of interv …
We explore options around deriving a consensus on how to define different forms of control and the longer term utility of achieving r …
Dopamine Receptors Differentially Control Binge Alcohol Drinking-Mediated Synaptic Plasticity of the Core Nucleus Accumbens Direct and Indirect Pathways.
Ji X, Saha S, Kolpakova J, Guildford M, Tapper AR, Martin GE. Ji X, et al. Among authors: martin ge. J Neurosci. 2017 May 31;37(22):5463-5474. doi: 10.1523/JNEUROSCI.3845-16.2017. Epub 2017 May 4. J Neurosci. 2017. PMID: 28473645 Free PMC article.
STDP in MSNs expressing dopamine D1 receptors shifted from spike-timing-dependent long-term depression (tLTD), the predominant form of plasticity in naive male mice, to spike-timing-dependent long-term potentiation (tLTP) in DID mice, an effect that was totally reve …
STDP in MSNs expressing dopamine D1 receptors shifted from spike-timing-dependent long-term depression (tLTD), the predominant form o …
The Sodium Channel beta4 Auxiliary Subunit Selectively Controls Long-Term Depression in Core Nucleus Accumbens Medium Spiny Neurons.
Ji X, Saha S, Gao G, Lasek AW, Homanics GE, Guildford M, Tapper AR, Martin GE. Ji X, et al. Among authors: martin ge. Front Cell Neurosci. 2017 Feb 13;11:17. doi: 10.3389/fncel.2017.00017. eCollection 2017. Front Cell Neurosci. 2017. PMID: 28243192 Free PMC article.
These alterations are associated with a reduction of the probability of MSNs to evoke spike-timing-dependent long-term depression (tLTD) and a reduced ability of backpropagating APs to evoke dendritic calcium transients. In contrast, long-term potentiation (tLTP) re …
These alterations are associated with a reduction of the probability of MSNs to evoke spike-timing-dependent long-term depression (tL …
The origin of glutamatergic synaptic inputs controls synaptic plasticity and its modulation by alcohol in mice nucleus accumbens.
Ji X, Saha S, Martin GE. Ji X, et al. Among authors: martin ge. Front Synaptic Neurosci. 2015 Jul 20;7:12. doi: 10.3389/fnsyn.2015.00012. eCollection 2015. Front Synaptic Neurosci. 2015. PMID: 26257641 Free PMC article.
We showed that the origin of synaptic inputs determines the basic properties of glutamatergic synaptic transmission, the expression of spike-timing dependent long-term depression (tLTD) and long-term potentiation (LTP) and long-term potentiation (tLTP) and th …
We showed that the origin of synaptic inputs determines the basic properties of glutamatergic synaptic transmission, the expression of spike …
BK channels mediate dopamine inhibition of firing in a subpopulation of core nucleus accumbens medium spiny neurons.
Ji X, Martin GE. Ji X, et al. Among authors: martin ge. Brain Res. 2014 Nov 7;1588:1-16. doi: 10.1016/j.brainres.2014.09.015. Epub 2014 Sep 16. Brain Res. 2014. PMID: 25219484 Free PMC article.
This effect, observed only in about 25% of all neurons, was associated with spike-timing-dependent (STDP) long-term potentiation (tLTP), but not long-term depression (tLTD). Dopamine inhibits evoked firing by compromising subthreshold depolarization, not by altering …
This effect, observed only in about 25% of all neurons, was associated with spike-timing-dependent (STDP) long-term potentiation (tLT …
New rules governing synaptic plasticity in core nucleus accumbens medium spiny neurons.
Ji X, Martin GE. Ji X, et al. Among authors: martin ge. Eur J Neurosci. 2012 Dec;36(12):3615-27. doi: 10.1111/ejn.12002. Epub 2012 Sep 26. Eur J Neurosci. 2012. PMID: 23013293 Free PMC article.
To date, attempts at understanding the relationship between drugs of abuse and synaptic plasticity have relied on the high-frequency long-term potentiation model of T.V. Bliss & T. Lomo [(1973) Journal of Physiology, 232, 331-356]. ...In contrast to other brain regions …
To date, attempts at understanding the relationship between drugs of abuse and synaptic plasticity have relied on the high-frequency long- …
Narrative Skill in Boys with Fragile X Syndrome with and without Autism Spectrum Disorder.
Estigarribia B, Martin GE, Roberts JE, Spencer A, Gucwa A, Sideris J. Estigarribia B, et al. Among authors: martin ge. Appl Psycholinguist. 2011;32(2):359-388. doi: 10.1017/S0142716410000445. Appl Psycholinguist. 2011. PMID: 21516264 Free PMC article.
Narratives were scored for mentions of macrostructural Story Grammar elements (Introduction, Relationship, Initiating Events, Internal Response, Attempts/Actions, and Ending). We found that narrative recall is predicted by short-term memory and nonverbal mental age levels …
Narratives were scored for mentions of macrostructural Story Grammar elements (Introduction, Relationship, Initiating Events, Internal Respo …
Fuzzy structure generation: a new efficient tool for Computer-Aided Structure Elucidation (CASE).
Elyashberg ME, Blinov KA, Molodtsov SG, Williams AJ, Martin GE. Elyashberg ME, et al. Among authors: martin ge. J Chem Inf Model. 2007 May-Jun;47(3):1053-66. doi: 10.1021/ci600528g. Epub 2007 Mar 27. J Chem Inf Model. 2007. PMID: 17385849
Unfortunately nonstandard correlations and the number of intervening bonds usually cannot be identified experimentally. In this work we suggest a new approach that we term Fuzzy Structure Generation. This allows the solution of structural problems whose 2D NMR data contain …
Unfortunately nonstandard correlations and the number of intervening bonds usually cannot be identified experimentally. In this work we sugg …
Chronic proglumide increases [3H]spiperone binding in the rat brain.
Bean AJ, Baldy WJ Jr, Martin GE. Bean AJ, et al. Among authors: martin ge. Eur J Pharmacol. 1985 Oct 29;117(1):97-101. doi: 10.1016/0014-2999(85)90476-5. Eur J Pharmacol. 1985. PMID: 4085545
., proglumide failed to alter the binding of [3H]spiperone to rat striatal tissue. These data indicate long-term proglumide administration increases the number of binding sites for [3H]spiperone, thought to be a ligand for dopamine D-2 receptors....
., proglumide failed to alter the binding of [3H]spiperone to rat striatal tissue. These data indicate long-term proglumide administr …