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Probability of major depression diagnostic classification based on the SCID, CIDI and MINI diagnostic interviews controlling for Hospital Anxiety and Depression Scale - Depression subscale scores: An individual participant data meta-analysis of 73 primary studies.
Wu Y, Levis B, Sun Y, Krishnan A, He C, Riehm KE, Rice DB, Azar M, Yan XW, Neupane D, Bhandari PM, Imran M, Chiovitti MJ, Saadat N, Boruff JT, Cuijpers P, Gilbody S, McMillan D, Ioannidis JPA, Kloda LA, Patten SB, Shrier I, Ziegelstein RC, Henry M, Ismail Z, Loiselle CG, Mitchell ND, Tonelli M, Al-Adawi S, Beraldi A, Braeken APBM, Büel-Drabe N, Bunevicius A, Carter G, Chen CK, Cheung G, Clover K, Conroy RM, Cukor D, da Rocha E Silva CE, Dabscheck E, Daray FM, Douven E, Downing MG, Feinstein A, Ferentinos PP, Fischer FH, Flint AJ, Fujimori M, Gallagher P, Gandy M, Goebel S, Grassi L, Härter M, Jenewein J, Jetté N, Julião M, Kim JM, Kim SW, Kjærgaard M, Köhler S, Loosman WL, Löwe B, Martin-Santos R, Massardo L, Matsuoka Y, Mehnert A, Michopoulos I, Misery L, Navines R, O'Donnell ML, Öztürk A, Peceliuniene J, Pintor L, Ponsford JL, Quinn TJ, Reme SE, Reuter K, Rooney AG, Sánchez-González R, Schwarzbold ML, Senturk Cankorur V, Shaaban J, Sharpe L, Sharpe M, Simard S, Singer S, Stafford L, Stone J, Sultan S, Teixeira AL, Tiringer I, Turner A, Walker J, Walterfang M, Wang LJ, White J, Wong DK, Benedetti A, Thombs BD. Wu Y, et al. Among authors: martin santos r. J Psychosom Res. 2020 Feb;129:109892. doi: 10.1016/j.jpsychores.2019.109892. Epub 2019 Dec 13. J Psychosom Res. 2020. PMID: 31911325
We fit binomial generalized linear mixed models to compare odds of major depression classification for the Structured Clinical Interview for DSM (SCID), Composite International Diagnostic Interview (CIDI), and Mini International Neuropsychiatric Interview (MINI), controlling for …
We fit binomial generalized linear mixed models to compare odds of major depression classification for the Structured Clinical Interview for …
Modulation of the Endocannabinoid and Oxytocinergic Systems as a Potential Treatment Approach for Social Anxiety Disorder.
Dos Santos RG, de Lima Osório F, Martin-Santos R, Zuardi AW, Hallak JEC, Crippa JAS. Dos Santos RG, et al. Among authors: martin santos r. CNS Drugs. 2019 Oct;33(10):1031-1038. doi: 10.1007/s40263-019-00669-5. CNS Drugs. 2019. PMID: 31617149 Review.
Therefore, future studies should explore the anxiolytic potential of these compounds using long-term, placebo-controlled designs with larger samples to elucidate the possible use of these compounds in the treatment of SAD....
Therefore, future studies should explore the anxiolytic potential of these compounds using long-term, placebo-controlled designs with …
Clinical Lactation Studies of Lithium: A Systematic Review.
Imaz ML, Torra M, Soy D, García-Esteve L, Martin-Santos R. Imaz ML, et al. Among authors: martin santos r. Front Pharmacol. 2019 Sep 10;10:1005. doi: 10.3389/fphar.2019.01005. eCollection 2019. Front Pharmacol. 2019. PMID: 31551795 Free PMC article.
Aims: We conducted a systematic review of the current evidence of studies assessing the transfer of lithium to lactating infants and short-term infant outcomes. Methods: An a priori protocol was designed based on PRISMA guidelines. ...Studies assessing lithium pharmacokine …
Aims: We conducted a systematic review of the current evidence of studies assessing the transfer of lithium to lactating infants and short- …
Cortical surface morphology in long-term cannabis users: A multi-site MRI study.
Chye Y, Suo C, Lorenzetti V, Batalla A, Cousijn J, Goudriaan AE, Martin-Santos R, Whittle S, Solowij N, Yücel M. Chye Y, et al. Among authors: martin santos r. Eur Neuropsychopharmacol. 2019 Dec;29(2):257-265. doi: 10.1016/j.euroneuro.2018.11.1110. Epub 2018 Dec 14. Eur Neuropsychopharmacol. 2019. PMID: 30558823
Careful reevaluation of the evidence on cannabis-related harm will be necessary to address concerns surrounding the long-term effects of cannabis use and inform policies in a changing cannabis regulation climate....
Careful reevaluation of the evidence on cannabis-related harm will be necessary to address concerns surrounding the long-term effects …
Antidepressant Efficacy and Tolerability of Ketamine and Esketamine: A Critical Review.
Molero P, Ramos-Quiroga JA, Martin-Santos R, Calvo-Sánchez E, Gutiérrez-Rojas L, Meana JJ. Molero P, et al. Among authors: martin santos r. CNS Drugs. 2018 May;32(5):411-420. doi: 10.1007/s40263-018-0519-3. CNS Drugs. 2018. PMID: 29736744 Review.
Proof-of-concept single-dose and repeat-dose studies with intravenous ketamine show a significant antidepressant and probably antisuicidal effect in the short term, with response rates over 60% as early as 4.5 h after a single dose, with a sustained effect after 24 h, and …
Proof-of-concept single-dose and repeat-dose studies with intravenous ketamine show a significant antidepressant and probably antisuicidal e …
The Associations Between Oxytocin and Trauma in Humans: A Systematic Review.
Donadon MF, Martin-Santos R, Osório FL. Donadon MF, et al. Among authors: martin santos r. Front Pharmacol. 2018 Mar 1;9:154. doi: 10.3389/fphar.2018.00154. eCollection 2018. Front Pharmacol. 2018. PMID: 29545749 Free PMC article. Review.
Studies have shown that traumatic experiences may affect hormonal systems mediated by the hypothalamic-pituitary-adrenal (HPA) axis and the oxytocinergic system. This effect is the result of long-term impairments in hypothalamic structures and negative feedback mechanisms …
Studies have shown that traumatic experiences may affect hormonal systems mediated by the hypothalamic-pituitary-adrenal (HPA) axis and the …
Cytokine-induced depression: current status and novel targets for depression therapy.
Udina M, Moreno-España J, Capuron L, Navinés R, Farré M, Vieta E, Martín-Santos R. Udina M, et al. Among authors: martin santos r. CNS Neurol Disord Drug Targets. 2014;13(6):1066-74. doi: 10.2174/1871527313666140612121921. CNS Neurol Disord Drug Targets. 2014. PMID: 24923336 Review.
Overall, these treatments have demonstrated an ability to manage major depression but otucomes continue to be poor in many patients, especially those with long term illness or with previous multiple relapses. This may be due to the fact that depression is a systemic and ne …
Overall, these treatments have demonstrated an ability to manage major depression but otucomes continue to be poor in many patients, especia …
The influence of genetic and environmental factors among MDMA users in cognitive performance.
Cuyàs E, Verdejo-García A, Fagundo AB, Khymenets O, Rodríguez J, Cuenca A, de Sola Llopis S, Langohr K, Peña-Casanova J, Torrens M, Martín-Santos R, Farré M, de la Torre R. Cuyàs E, et al. Among authors: martin santos r. PLoS One. 2011;6(11):e27206. doi: 10.1371/journal.pone.0027206. Epub 2011 Nov 16. PLoS One. 2011. PMID: 22110616 Free PMC article.
Hormonal responses to the 5-HT1A agonist buspirone in remitted endogenous depressive patients after long-term imipramine treatment.
Gómez-Gil E, Navinés R, Martínez De Osaba MJ, Díaz-Ricart M, Escolar G, Salamero M, Martín-Santos R, Galán A, Gastó C. Gómez-Gil E, et al. Among authors: martin santos r. Psychoneuroendocrinology. 2010 May;35(4):481-9. doi: 10.1016/j.psyneuen.2009.08.012. Epub 2009 Sep 16. Psychoneuroendocrinology. 2010. PMID: 19762159 Clinical Trial.
As the direction of change in ACTH-cortisol and PRL responses after treatment is the opposite, we cannot substantiate increases or decreases in the sensitivity of post-synaptic 5-HT1A receptors in the hypothalamus by long-term imipramine treatment and/or resolution of illn …
As the direction of change in ACTH-cortisol and PRL responses after treatment is the opposite, we cannot substantiate increases or decreases …
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