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Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency.
Hanna J, Markoulaki S, Schorderet P, Carey BW, Beard C, Wernig M, Creyghton MP, Steine EJ, Cassady JP, Foreman R, Lengner CJ, Dausman JA, Jaenisch R. Hanna J, et al. Among authors: markoulaki s. Cell. 2008 Apr 18;133(2):250-64. doi: 10.1016/j.cell.2008.03.028. Cell. 2008. PMID: 18423197 Free PMC article.
Multiple iPS lines were clonally derived from both nonfully and fully differentiated B lymphocytes, which gave rise to adult chimeras with germline contribution, and to late-term embryos when injected into tetraploid blastocysts. Our study provides definite proof for the d …
Multiple iPS lines were clonally derived from both nonfully and fully differentiated B lymphocytes, which gave rise to adult chimeras with g …
Fertilization stimulates long-lasting oscillations of CaMKII activity in mouse eggs.
Markoulaki S, Matson S, Ducibella T. Markoulaki S, et al. Dev Biol. 2004 Aug 1;272(1):15-25. doi: 10.1016/j.ydbio.2004.04.008. Dev Biol. 2004. PMID: 15242787 Free article.
The contribution of CaMKII from a single sperm to the rise in CaMKII activity at fertilization appeared to be negligible. Also, long-term cell cycle inhibition was observed in fertilized eggs with the CaMKII antagonist myrAIP (50 microM), which did not inhibit the first la …
The contribution of CaMKII from a single sperm to the rise in CaMKII activity at fertilization appeared to be negligible. Also, long-term …