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203 results

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Breast cancer incidence and mortality by metabolic syndrome and obesity: The Women's Health Initiative.
Chlebowski RT, Aragaki AK, Pan K, Simon MS, Neuhouser ML, Haque R, Rohan TE, Wactawski-Wende J, Orchard TS, Mortimer JE, Lane D, Kaunitz AM, Desai P, Wild RA, Barac A, Manson JE. Chlebowski RT, et al. Among authors: manson je. Cancer. 2024 May 13. doi: 10.1002/cncr.35318. Online ahead of print. Cancer. 2024. PMID: 38736319
Therefore, this study investigated the associations of MetS and obesity with postmenopausal breast cancer after long-term follow-up in the WHI clinical trials. METHODS: A total of 68,132 postmenopausal women, without prior breast cancer and with normal mammogram, were ente …
Therefore, this study investigated the associations of MetS and obesity with postmenopausal breast cancer after long-term follow-up i …
Use of melatonin supplements and risk of type 2 diabetes and cardiovascular diseases in the USA: insights from three prospective cohort studies.
Li Y, Huang T, Redline S, Willett WC, Manson JE, Schernhammer ES, Hu FB. Li Y, et al. Among authors: manson je. Lancet Diabetes Endocrinol. 2024 May 3:S2213-8587(24)00096-2. doi: 10.1016/S2213-8587(24)00096-2. Online ahead of print. Lancet Diabetes Endocrinol. 2024. PMID: 38710189
BACKGROUND: Use of melatonin supplements has been increasing substantially in both children and adults in the USA; however, their long-term cardiometabolic effects remain unclear. We aimed to assess the associations between regular use of melatonin supplements and the risk …
BACKGROUND: Use of melatonin supplements has been increasing substantially in both children and adults in the USA; however, their long-te …
The Women's Health Initiative Randomized Trials and Clinical Practice: A Review.
Manson JE, Crandall CJ, Rossouw JE, Chlebowski RT, Anderson GL, Stefanick ML, Aragaki AK, Cauley JA, Wells GL, LaCroix AZ, Thomson CA, Neuhouser ML, Van Horn L, Kooperberg C, Howard BV, Tinker LF, Wactawski-Wende J, Shumaker SA, Prentice RL. Manson JE, et al. JAMA. 2024 May 1. doi: 10.1001/jama.2024.6542. Online ahead of print. JAMA. 2024. PMID: 38691368
A low-fat dietary pattern with increased fruit, vegetable, and grain consumption did not prevent the primary outcomes of breast or colorectal cancer but was associated with lower rates of the secondary outcome of breast cancer mortality during long-term follow-up. CONCLUSI …
A low-fat dietary pattern with increased fruit, vegetable, and grain consumption did not prevent the primary outcomes of breast or colorecta …
Long-Term Effect of Randomization to Calcium and Vitamin D Supplementation on Health in Older Women : Postintervention Follow-up of a Randomized Clinical Trial.
Thomson CA, Aragaki AK, Prentice RL, Stefanick ML, Manson JE, Wactawski-Wende J, Watts NB, Van Horn L, Shikany JM, Rohan TE, Lane DS, Wild RA, Robles-Morales R, Shadyab AH, Saquib N, Cauley J. Thomson CA, et al. Among authors: manson je. Ann Intern Med. 2024 Apr;177(4):428-438. doi: 10.7326/M23-2598. Epub 2024 Mar 12. Ann Intern Med. 2024. PMID: 38467003 Clinical Trial.
BACKGROUND: Although calcium and vitamin D (CaD) supplementation may affect chronic disease in older women, evidence of long-term effects on health outcomes is limited. OBJECTIVE: To evaluate long-term health outcomes among postmenopausal women in the Women's Health …
BACKGROUND: Although calcium and vitamin D (CaD) supplementation may affect chronic disease in older women, evidence of long-term eff …
Effect of cocoa extract supplementation on cognitive function: results from the clinic subcohort of the COSMOS trial.
Vyas CM, Manson JE, Sesso HD, Rist PM, Weinberg A, Kim E, Moorthy MV, Cook NR, Okereke OI. Vyas CM, et al. Among authors: manson je. Am J Clin Nutr. 2024 Jan;119(1):39-48. doi: 10.1016/j.ajcnut.2023.10.031. Epub 2023 Dec 7. Am J Clin Nutr. 2024. PMID: 38070683 Clinical Trial.
BACKGROUND: Some prior randomized clinical trials (RCTs) that tested the effects of cocoa extract (CE), a source of flavanols, on late-life cognition have yielded promising findings. A long-term RCT using in-person neuropsychological tests covering multiple cognitive domai …
BACKGROUND: Some prior randomized clinical trials (RCTs) that tested the effects of cocoa extract (CE), a source of flavanols, on late-life …
Individual and Neighborhood-level Socioeconomic Status and Somatic Mutations Associated With Increased Risk of Cardiovascular Disease and Mortality: A Cross-Sectional Analysis in the Women's Health Initiative.
Love SM, Collins JM, Anthony KM, Buchheit SF, Butler EN, Bey GS, Gondalia R, Hayden KM, Zannas AS, Bick AG, Manson JE, Desai PM, Natarajan P, Bhattacharya R, Jaiswal S, Barac A, Reiner A, Kooperberg C, Stewart JD, Whitsel EA. Love SM, et al. Among authors: manson je. Womens Health Issues. 2024 Mar-Apr;34(2):197-207. doi: 10.1016/j.whi.2023.10.005. Epub 2023 Dec 6. Womens Health Issues. 2024. PMID: 38061917
CONCLUSIONS: Our findings suggest that reduced risk of somatic mutation may represent a biological pathway by which optimism protects contextually advantaged but at-risk women against age-related chronic disease and highlight potential benefits of long-term, positive psych …
CONCLUSIONS: Our findings suggest that reduced risk of somatic mutation may represent a biological pathway by which optimism protects contex …
Association between Noise and Cardiovascular Disease in a Nationwide U.S. Prospective Cohort Study of Women Followed from 1988 to 2018.
Roscoe C, Grady ST, Hart JE, Iyer HS, Manson JE, Rexrode KM, Rimm EB, Laden F, James P. Roscoe C, et al. Among authors: manson je. Environ Health Perspect. 2023 Dec;131(12):127005. doi: 10.1289/EHP12906. Epub 2023 Dec 4. Environ Health Perspect. 2023. PMID: 38048103 Free PMC article.
BACKGROUND: Long-term noise exposure is associated with cardiovascular disease (CVD), including acute cardiovascular events such as myocardial infarction and stroke. ...We aimed to examine the prospective association of outdoor long-term nighttime and daytime noise …
BACKGROUND: Long-term noise exposure is associated with cardiovascular disease (CVD), including acute cardiovascular events such as m …
Phytosterol intake and risk of coronary artery disease: Results from 3 prospective cohort studies.
Wang Y, Liu B, Hu Y, Sampson L, Manson JE, Rimm EB, Sun Q. Wang Y, et al. Among authors: manson je. Am J Clin Nutr. 2024 Feb;119(2):344-353. doi: 10.1016/j.ajcnut.2023.11.020. Epub 2023 Dec 1. Am J Clin Nutr. 2024. PMID: 38042410
In a subset of participants (N range between 11,983 and 22,039), phytosterol intake was inversely associated with plasma concentrations of total cholesterol, triglycerides, high-density lipoprotein cholesterol, and IL-6 and positively associated with adiponectin, whereas no signi …
In a subset of participants (N range between 11,983 and 22,039), phytosterol intake was inversely associated with plasma concentrations of t …
Cardiometabolic outcomes in Kronos Early Estrogen Prevention Study continuation: 14-year follow-up of a hormone therapy trial.
Kantarci K, Tosakulwong N, Lesnick TG, Kara F, Kendall-Thomas J, Kapoor E, Fields JA, James TT, Lobo RA, Manson JE, Pal L, Hammers DB, Malek-Ahmadi M, Cedars MI, Naftolin FN, Santoro N, Miller VM, Harman SM, Dowling NM, Gleason CE. Kantarci K, et al. Among authors: manson je. Menopause. 2024 Jan 1;31(1):10-17. doi: 10.1097/GME.0000000000002278. Epub 2023 Nov 21. Menopause. 2024. PMID: 37989141
OBJECTIVE: This study aimed to determine long-term cardiometabolic effects of hormone therapies initiated within 3 years of onset of menopause after a 14-year follow-up study of participants of the Kronos Early Estrogen Prevention Study (KEEPS). ...
OBJECTIVE: This study aimed to determine long-term cardiometabolic effects of hormone therapies initiated within 3 years of onset of …
Portfolio Diet Score and Risk of Cardiovascular Disease: Findings From 3 Prospective Cohort Studies.
Glenn AJ, Guasch-Ferré M, Malik VS, Kendall CWC, Manson JE, Rimm EB, Willett WC, Sun Q, Jenkins DJA, Hu FB, Sievenpiper JL. Glenn AJ, et al. Among authors: manson je. Circulation. 2023 Nov 28;148(22):1750-1763. doi: 10.1161/CIRCULATIONAHA.123.065551. Epub 2023 Oct 25. Circulation. 2023. PMID: 37877288
BACKGROUND: The plant-based Portfolio dietary pattern includes recognized cholesterol-lowering foods (ie, plant protein, nuts, viscous fiber, phytosterols, and plant monounsaturated fats) shown to improve several cardiovascular disease (CVD) risk factors in randomized controlled …
BACKGROUND: The plant-based Portfolio dietary pattern includes recognized cholesterol-lowering foods (ie, plant protein, nuts, viscous fiber …
203 results