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A FACS-based novel isolation technique identifies heterogeneous CTCs in oral squamous cell carcinoma.
Chauhan A, Pal A, Sachdeva M, Boora GS, Parsana M, Bakshi J, Verma RK, Srinivasan R, Chatterjee D, Maitra A, Ghoshal S. Chauhan A, et al. Among authors: maitra a. Front Oncol. 2024 Feb 26;14:1269211. doi: 10.3389/fonc.2024.1269211. eCollection 2024. Front Oncol. 2024. PMID: 38469233 Free PMC article.
Isolated CTCs were also found to be suitable for downstream applications like short-term CTC culture and RNA-Seq. CONCLUSION: We developed a sensitive, specific, flexible, and affordable CTC detection/isolation technique, which is scalable to larger patient cohorts, provid …
Isolated CTCs were also found to be suitable for downstream applications like short-term CTC culture and RNA-Seq. CONCLUSION: We deve …
Comparative Analyses of the Clinicopathologic Features of Short-Term and Long-Term Survivors of Patients with Pancreatic Ductal Adenocarcinoma Who Received Neoadjuvant Therapy and Pancreatoduodenectomy.
Liang TZ, Katz MHG, Prakash LR, Chatterjee D, Wang H, Kim M, Tzeng CD, Ikoma N, Wolff RA, Zhao D, Koay EJ, Maitra A, Kundu S, Wang H. Liang TZ, et al. Among authors: maitra a. Cancers (Basel). 2023 Jun 18;15(12):3231. doi: 10.3390/cancers15123231. Cancers (Basel). 2023. PMID: 37370842 Free PMC article.
The ypN stage is an independent predictor of both short-term and long-term survivors by multivariate logistic regression analyses. In addition, tumor differentiation was also an independent predictor for short-term survivors, and tumor response grading and pe …
The ypN stage is an independent predictor of both short-term and long-term survivors by multivariate logistic regression analy …
Genome-wide temporal landscaping of DNA methylation in pregnant women delivering at term: a GARBH-InI study.
Das J, Wadhwa N, Natchu UC, Thiruvengadam R, Kshetrapal P, Bhatnagar S, Majumder PP, Maitra A. Das J, et al. Among authors: maitra a. Epigenomics. 2023 May;15(9):543-556. doi: 10.2217/epi-2023-0145. Epub 2023 Jun 21. Epigenomics. 2023. PMID: 37345372
Conclusion: Consistent trends of DNA methylation in maternal peripheral blood point to the sentinel function of T cells in the maintenance of pregnancy, and the importance of coordinated cellular remodeling to facilitate term delivery. DNA methylation is the addition of a …
Conclusion: Consistent trends of DNA methylation in maternal peripheral blood point to the sentinel function of T cells in the maintenance o …
The Vaginal Microbial Signatures of Preterm Birth Delivery in Indian Women.
Kumar S, Kumari N, Talukdar D, Kothidar A, Sarkar M, Mehta O, Kshetrapal P, Wadhwa N, Thiruvengadam R, Desiraju BK, Nair GB, Bhatnagar S, Mukherjee S, Das B; GARBH-Ini Study Group. Kumar S, et al. Front Cell Infect Microbiol. 2021 May 13;11:622474. doi: 10.3389/fcimb.2021.622474. eCollection 2021. Front Cell Infect Microbiol. 2021. PMID: 34094994 Free PMC article.
OBJECTIVE: Conduct a comparative analysis of vaginal microbiome composition and microbial genomic repertoires of women who enrolled in the Interdisciplinary Group for Advanced Research on Birth Outcomes - A DBT India Initiative (GARBH-Ini) pregnancy cohort to identify bact …
OBJECTIVE: Conduct a comparative analysis of vaginal microbiome composition and microbial genomic repertoires of women who enrolled in the I …
Selumetinib: the first ever approved drug for neurofibromatosis-1 related inoperable plexiform neurofibroma.
Mukhopadhyay S, Maitra A, Choudhury S. Mukhopadhyay S, et al. Among authors: maitra a. Curr Med Res Opin. 2021 May;37(5):789-794. doi: 10.1080/03007995.2021.1900089. Epub 2021 Mar 23. Curr Med Res Opin. 2021. PMID: 33683166
The major limitation of this molecule regarding its mechanism of action is the dose-dependent effect of MEK inhibition in growth of neurofibroma. Long-term safety and efficacy studies are to be done in the future to establish selumetininb as a useful medicine....
The major limitation of this molecule regarding its mechanism of action is the dose-dependent effect of MEK inhibition in growth of neurofib …
Cost-effectiveness of consensus guideline based management of pancreatic cysts: The sensitivity and specificity required for guidelines to be cost-effective.
Sharib J, Esserman L, Koay EJ, Maitra A, Shen Y, Kirkwood KS, Ozanne EM. Sharib J, et al. Among authors: maitra a. Surgery. 2020 Oct;168(4):601-609. doi: 10.1016/j.surg.2020.04.052. Epub 2020 Jul 29. Surgery. 2020. PMID: 32739138 Free PMC article.
Most importantly, survival in surveillance is worse than "do nothing" for 3 years after cyst diagnosis, although long-term survival is improved. The disadvantage is eliminated when overtreatment of low-grade cysts is avoided. ...
Most importantly, survival in surveillance is worse than "do nothing" for 3 years after cyst diagnosis, although long-term survival i …
Salivary proteome signatures in the early and middle stages of human pregnancy with term birth outcome.
Dey AK, Kumar B, Singh AK, Ranjan P, Thiruvengadam R, Desiraju BK, Kshetrapal P, Wadhwa N, Bhatnagar S, Rashid F, Malakar D, Salunke DM, Maiti TK; GARBH-Ini Study Group*. Dey AK, et al. Sci Rep. 2020 May 15;10(1):8022. doi: 10.1038/s41598-020-64483-6. Sci Rep. 2020. PMID: 32415095 Free PMC article.
The present prospective study aims to elucidate changes in salivary proteome from the early to middle stages of term pregnancy, and establishing an expressional trajectory for modulated proteins. ...Overall, the results not only demonstrate the longitudinal maternal saliva …
The present prospective study aims to elucidate changes in salivary proteome from the early to middle stages of term pregnancy, and e …
Pancreatic cancer stroma: an update on therapeutic targeting strategies.
Hosein AN, Brekken RA, Maitra A. Hosein AN, et al. Among authors: maitra a. Nat Rev Gastroenterol Hepatol. 2020 Aug;17(8):487-505. doi: 10.1038/s41575-020-0300-1. Epub 2020 May 11. Nat Rev Gastroenterol Hepatol. 2020. PMID: 32393771 Free PMC article. Review.
Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer-related mortality in the Western world with limited therapeutic options and dismal long-term survival. The neoplastic epithelium exists within a dense stroma, which is recognized as a critical mediator of …
Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer-related mortality in the Western world with limited therapeutic options …
Combination of PD-1 Inhibitor and OX40 Agonist Induces Tumor Rejection and Immune Memory in Mouse Models of Pancreatic Cancer.
Ma Y, Li J, Wang H, Chiu Y, Kingsley CV, Fry D, Delaney SN, Wei SC, Zhang J, Maitra A, Yee C. Ma Y, et al. Among authors: maitra a. Gastroenterology. 2020 Jul;159(1):306-319.e12. doi: 10.1053/j.gastro.2020.03.018. Epub 2020 Mar 14. Gastroenterology. 2020. PMID: 32179091 Free PMC article.
Mice with orthotopic tumors that were given the combination of anti-PD-1 and anti-OX40 and survived 100 days were rechallenged with a second tumor; those rechallenged with mT4 cells survived an additional median 70 days and those rechallenged with KPC-Luc cells survived long t …
Mice with orthotopic tumors that were given the combination of anti-PD-1 and anti-OX40 and survived 100 days were rechallenged with a second …
Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes.
Riquelme E, Zhang Y, Zhang L, Montiel M, Zoltan M, Dong W, Quesada P, Sahin I, Chandra V, San Lucas A, Scheet P, Xu H, Hanash SM, Feng L, Burks JK, Do KA, Peterson CB, Nejman D, Tzeng CD, Kim MP, Sears CL, Ajami N, Petrosino J, Wood LD, Maitra A, Straussman R, Katz M, White JR, Jenq R, Wargo J, McAllister F. Riquelme E, et al. Among authors: maitra a. Cell. 2019 Aug 8;178(4):795-806.e12. doi: 10.1016/j.cell.2019.07.008. Cell. 2019. PMID: 31398337 Free PMC article.
Here, we dissect the role of the tumor microbiota and the immune system in influencing long-term survival. Using 16S rRNA gene sequencing, we analyzed the tumor microbiome composition in PDAC patients with short-term survival (STS) and long-term survival (LTS …
Here, we dissect the role of the tumor microbiota and the immune system in influencing long-term survival. Using 16S rRNA gene sequen …
30 results