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Utility of Early Magnetic Resonance Imaging to Enhance Outcome Prediction in Critically Ill Children with Severe Traumatic Brain Injury.
Janas AM, Miller KR, Stence NV, Wyrwa JM, Ruzas CM, Messer R, Mourani PM, Fink EL, Maddux AB. Janas AM, et al. Among authors: maddux ab. Neurocrit Care. 2023 Dec 26. doi: 10.1007/s12028-023-01898-9. Online ahead of print. Neurocrit Care. 2023. PMID: 38148435
CONCLUSIONS: Regional restricted diffusion on early MRI is independently associated with short-term outcomes in children with severe TBI. Multicenter cohort studies are needed to validate these findings and elucidate the association of early MRI features with long-term …
CONCLUSIONS: Regional restricted diffusion on early MRI is independently associated with short-term outcomes in children with severe …
Infants Admitted to US Intensive Care Units for RSV Infection During the 2022 Seasonal Peak.
Halasa N, Zambrano LD, Amarin JZ, Stewart LS, Newhams MM, Levy ER, Shein SL, Carroll CL, Fitzgerald JC, Michaels MG, Bline K, Cullimore ML, Loftis L, Montgomery VL, Jeyapalan AS, Pannaraj PS, Schwarz AJ, Cvijanovich NZ, Zinter MS, Maddux AB, Bembea MM, Irby K, Zerr DM, Kuebler JD, Babbitt CJ, Gaspers MG, Nofziger RA, Kong M, Coates BM, Schuster JE, Gertz SJ, Mack EH, White BR, Harvey H, Hobbs CV, Dapul H, Butler AD, Bradford TT, Rowan CM, Wellnitz K, Staat MA, Aguiar CL, Hymes SR, Randolph AG, Campbell AP; RSV-PIC Investigators. Halasa N, et al. Among authors: maddux ab. JAMA Netw Open. 2023 Aug 1;6(8):e2328950. doi: 10.1001/jamanetworkopen.2023.28950. JAMA Netw Open. 2023. PMID: 37581884 Free PMC article.
CONCLUSIONS AND RELEVANCE: In this cross-sectional study, most US infants who required intensive care for RSV LRTIs were young, healthy, and born at term. These findings highlight the need for RSV preventive interventions targeting all infants to reduce the burden of sever …
CONCLUSIONS AND RELEVANCE: In this cross-sectional study, most US infants who required intensive care for RSV LRTIs were young, healthy, and …
Variation in Early Anakinra Use and Short-Term Outcomes in Multisystem Inflammatory Syndrome in Children.
Chang JC, Young CC, Muscal E, Sexson Tejtel SK, Newhams MM, Kucukak S, Crandall H, Maddux AB, Rowan CM, Halasa NB, Harvey HA, Hobbs CV, Hall MW, Kong M, Aguiar CL, Schuster JE, Fitzgerald JC, Singh AR, Wellnitz K, Nofziger RA, Cvijanovich NZ, Mack EH, Schwarz AJ, Heidemann SM, Newburger JW, Zambrano LD, Campbell AP, Patel MM, Randolph AG, Son MBF; Overcoming COVID-19 Investigators. Chang JC, et al. Among authors: maddux ab. Arthritis Rheumatol. 2023 Aug;75(8):1466-1476. doi: 10.1002/art.42495. Epub 2023 May 16. Arthritis Rheumatol. 2023. PMID: 36908050
CONCLUSION: We identified substantial variation in initial anakinra use in a real-world population of children with MIS-C, but no average short-term improvement in cardiovascular outcomes associated with early addition of anakinra to IVIG and/or glucocorticoids compared to …
CONCLUSION: We identified substantial variation in initial anakinra use in a real-world population of children with MIS-C, but no average sh …
Supporting families during pediatric critical illness: Opportunities identified in a multicenter, qualitative study.
Jarvis JM, Huntington T, Perry G, Zickmund S, Yang S, Galyean P, Pinto N, Watson RS, Olson LM, Fink EL, Maddux AB. Jarvis JM, et al. Among authors: maddux ab. J Child Health Care. 2023 Feb 7:13674935231154829. doi: 10.1177/13674935231154829. Online ahead of print. J Child Health Care. 2023. PMID: 36749657
Targeted, interdisciplinary approaches to partner with families during critical care may improve their PICU experience and contribute to improved long-term outcomes for PICU survivors....
Targeted, interdisciplinary approaches to partner with families during critical care may improve their PICU experience and contribute to imp …
Outcomes of Children Surviving Pediatric Acute Respiratory Distress Syndrome: From the Second Pediatric Acute Lung Injury Consensus Conference.
Killien EY, Maddux AB, Tse SM, Watson RS; Second Pediatric Acute Lung Injury Consensus Conference (PALICC-2) of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. Killien EY, et al. Among authors: maddux ab. Pediatr Crit Care Med. 2023 Feb 1;24(Supplement 1 2S):S28-S44. doi: 10.1097/PCC.0000000000003157. Epub 2023 Jan 20. Pediatr Crit Care Med. 2023. PMID: 36661434 Free PMC article. Review.
The five research statements relate to assessment of patient preillness status, use of postdischarge endpoints for clinical trials, the association between short-term and longer term outcomes, the trajectory of recovery following PARDS, and practices to optimize fol …
The five research statements relate to assessment of patient preillness status, use of postdischarge endpoints for clinical trials, the asso …
Unplanned Admissions, Emergency Department Visits, and Epilepsy After Critical Neurological Illness Requiring Prolonged Mechanical Ventilation in Children.
Spear MB, Miller K, Press C, Ruzas C, LaVelle J, Mourani PM, Bennett TD, Maddux AB. Spear MB, et al. Among authors: maddux ab. Neurohospitalist. 2023 Jan;13(1):31-39. doi: 10.1177/19418744221123628. Epub 2022 Oct 9. Neurohospitalist. 2023. PMID: 36531841 Free PMC article.
BACKGROUND AND PURPOSE: Long-term outcomes after pediatric neurocritical illness are poorly characterized. ...
BACKGROUND AND PURPOSE: Long-term outcomes after pediatric neurocritical illness are poorly characterized. ...
Association of Blood-Based Brain Injury Biomarker Concentrations With Outcomes After Pediatric Cardiac Arrest.
Fink EL, Kochanek PM, Panigrahy A, Beers SR, Berger RP, Bayir H, Pineda J, Newth C, Topjian AA, Press CA, Maddux AB, Willyerd F, Hunt EA, Siems A, Chung MG, Smith L, Wenger J, Doughty L, Diddle JW, Patregnani J, Piantino J, Walson KH, Balakrishnan B, Meyer MT, Friess S, Maloney D, Rubin P, Haller TL, Treble-Barna A, Wang C, Clark RRSB, Fabio A; Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators. Fink EL, et al. Among authors: maddux ab. JAMA Netw Open. 2022 Sep 1;5(9):e2230518. doi: 10.1001/jamanetworkopen.2022.30518. JAMA Netw Open. 2022. PMID: 36074465 Free PMC article.
IMPORTANCE: Families and clinicians have limited validated tools available to assist in estimating long-term outcomes early after pediatric cardiac arrest. Blood-based brain-specific biomarkers may be helpful tools to aid in outcome assessment. ...
IMPORTANCE: Families and clinicians have limited validated tools available to assist in estimating long-term outcomes early after ped …
A Core Outcome Measurement Set for Pediatric Critical Care.
Pinto NP, Maddux AB, Dervan LA, Woodruff AG, Jarvis JM, Nett S, Killien EY, Graham RJ, Choong K, Luckett PM, Heneghan JA, Biagas K, Carlton EF, Hartman ME, Yagiela L, Michelson KN, Manning JC, Long DA, Lee JH, Slomine BS, Beers SR, Hall T, Morrow BM, Meert K, Arias Lopez MDP, Knoester H, Houtrow A, Olson L, Steele L, Schlapbach LJ, Burd RS, Grosskreuz R, Butt W, Fink EL, Watson RS; POST-PICU Investigators of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network and the Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN). Pinto NP, et al. Among authors: maddux ab. Pediatr Crit Care Med. 2022 Nov 1;23(11):893-907. doi: 10.1097/PCC.0000000000003055. Epub 2022 Aug 29. Pediatr Crit Care Med. 2022. PMID: 36040097 Free PMC article.
CONCLUSIONS: The PICU COMS delineates measures to evaluate domains in the PICU COS and facilitates comparability across future research studies to characterize PICU survivorship and enable interventional studies to target long-term outcomes after critical illness....
CONCLUSIONS: The PICU COMS delineates measures to evaluate domains in the PICU COS and facilitates comparability across future research stud …
Peripheral Vasoactive Administration in Critically Ill Children With Shock: A Single-Center Retrospective Cohort Study.
Levy RA, Reiter PD, Spear M, Santana A, Silveira L, Cox S, Mourani PM, Maddux AB. Levy RA, et al. Among authors: maddux ab. Pediatr Crit Care Med. 2022 Aug 1;23(8):618-625. doi: 10.1097/PCC.0000000000002970. Epub 2022 Apr 21. Pediatr Crit Care Med. 2022. PMID: 35446810 Free PMC article.
Three patients received pharmacologic intervention, and none had long-term disabilities. CONCLUSIONS: In our experience, peripheral venous catheters can be used for vasoactive administration. ...
Three patients received pharmacologic intervention, and none had long-term disabilities. CONCLUSIONS: In our experience, peripheral v …
14 results