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Reversible aberrancies in gut microbiome of moderate and late preterm infants: results from a randomized, controlled trial.
Luoto R, Pärtty A, Vogt JK, Rautava S, Isolauri E. Luoto R, et al. Gut Microbes. 2023 Dec;15(2):2283913. doi: 10.1080/19490976.2023.2283913. Epub 2023 Nov 27. Gut Microbes. 2023. PMID: 38010080 Free PMC article. Clinical Trial.
In addition, 9 full-term, vaginally delivered, breast-fed infants, who remained healthy long-term were included as references. Significant differences in taxonomy, but not in functional potential, were found when comparing the gut microbiome composition of preterm a …
In addition, 9 full-term, vaginally delivered, breast-fed infants, who remained healthy long-term were included as references. …
Finnish paediatric study found a low incidence of bacterial meningitis from 2011 to 2018 but a substantial proportion of nosocomial meningitis.
Niemelä S, Lempinen L, Löyttyniemi E, Grönroos JO, Luoto R, Peltola V, Jero J. Niemelä S, et al. Among authors: luoto r. Acta Paediatr. 2024 Feb;113(2):327-335. doi: 10.1111/apa.16991. Epub 2023 Oct 6. Acta Paediatr. 2024. PMID: 37800382
CONCLUSION: The incidence of paediatric BM was low during the study period, but the proportion of nosocomial meningitis was substantial. The frequency of unfavourable long-term outcomes was relatively low....
CONCLUSION: The incidence of paediatric BM was low during the study period, but the proportion of nosocomial meningitis was substantial. The …
Memory B Cell Activation Induced by Pertussis Booster Vaccination in Four Age Groups of Three Countries.
Versteegen P, Barkoff AM, Valente Pinto M, van de Kasteele J, Knuutila A, Bibi S, de Rond L, Teräsjärvi J, Sanders K, de Zeeuw-Brouwer ML, Luoto R, Ten Hulscher H, Clutterbuck EA, Sanders EAM, Mertsola J, Berbers GAM, He Q, Kelly DF, Buisman AM; PERISCOPE Consortium. Versteegen P, et al. Among authors: luoto r. Front Immunol. 2022 May 23;13:864674. doi: 10.3389/fimmu.2022.864674. eCollection 2022. Front Immunol. 2022. PMID: 35677044 Free PMC article. Clinical Trial.
BACKGROUND: Immunogenicity of acellular pertussis (aP) vaccines is conventionally assessed by measuring antibody responses but antibody concentrations wane quickly after vaccination. Memory B cells, however, are critical in sustaining long-term protection and therefore may …
BACKGROUND: Immunogenicity of acellular pertussis (aP) vaccines is conventionally assessed by measuring antibody responses but antibody conc …
Respiratory Viral Infections in Athletes: Many Unanswered Questions.
Ruuskanen O, Luoto R, Valtonen M, Heinonen OJ, Waris M. Ruuskanen O, et al. Among authors: luoto r. Sports Med. 2022 Sep;52(9):2013-2021. doi: 10.1007/s40279-022-01660-9. Epub 2022 Mar 30. Sports Med. 2022. PMID: 35353361 Free PMC article.
Immunity to respiratory viral infections is highly complex, and there is a lack of evidence that minor short- or long-term alterations in immunity in elite athletes have clinical implications. ...
Immunity to respiratory viral infections is highly complex, and there is a lack of evidence that minor short- or long-term alteration …
Preterm infant meconium microbiota transplant induces growth failure, inflammatory activation, and metabolic disturbances in germ-free mice.
Hiltunen H, Hanani H, Luoto R, Turjeman S, Ziv O, Isolauri E, Salminen S, Koren O, Rautava S. Hiltunen H, et al. Among authors: luoto r. Cell Rep Med. 2021 Nov 16;2(11):100447. doi: 10.1016/j.xcrm.2021.100447. eCollection 2021 Nov 16. Cell Rep Med. 2021. PMID: 34841294 Free PMC article.
Our results indicate that very preterm birth is associated with a distinct meconium microbiota composition. Fecal microbiota transplant of very preterm infant meconium results in impaired growth, altered intestinal immune function, and metabolic parameters as compared to …
Our results indicate that very preterm birth is associated with a distinct meconium microbiota composition. Fecal microbiota transpla …
Physical Activity and Body Composition in Children and Their Mothers According to Mother's Gestational Diabetes Risk: A Seven-Year Follow-Up Study.
Leppänen MH, Raitanen J, Husu P, Kujala UM, Tuominen PP, Vähä-Ypyä H, Luoto R. Leppänen MH, et al. Among authors: luoto r. Medicina (Kaunas). 2019 Sep 25;55(10):635. doi: 10.3390/medicina55100635. Medicina (Kaunas). 2019. PMID: 31557895 Free PMC article. Clinical Trial.
Conclusion: Health promotion should be targeted at women with GDM risk factors, in particular overweight women, in enhancing women's PA in the long term and their children's healthy body composition....
Conclusion: Health promotion should be targeted at women with GDM risk factors, in particular overweight women, in enhancing women's PA in t …
The effects of dietary and lifestyle interventions among pregnant women who are overweight or obese on longer-term maternal and early childhood outcomes: protocol for an individual participant data (IPD) meta-analysis.
Dodd JM, Grivell RM, Louise J, Deussen AR, Giles L, Mol BW, Vinter C, Tanvig M, Jensen DM, Bogaerts A, Devlieger R, Luoto R, McAuliffe F, Renault K, Carlsen E, Geiker N, Poston L, Briley A, Thangaratinam S, Rogozinska E, Owens JA. Dodd JM, et al. Among authors: luoto r. Syst Rev. 2017 Mar 9;6(1):51. doi: 10.1186/s13643-017-0442-6. Syst Rev. 2017. PMID: 28274270 Free PMC article.
Effectiveness and Cost-Effectiveness of a Cluster-Randomized Prenatal Lifestyle Counseling Trial: A Seven-Year Follow-Up.
Kolu P, Raitanen J, Puhkala J, Tuominen P, Husu P, Luoto R. Kolu P, et al. Among authors: luoto r. PLoS One. 2016 Dec 9;11(12):e0167759. doi: 10.1371/journal.pone.0167759. eCollection 2016. PLoS One. 2016. PMID: 27936083 Free PMC article. Clinical Trial.
There is a link between the pregnancy and its long-term influence on health and susceptibility to future chronic disease both in mother and offspring. ...Intervention was cost-effective in terms of sickness absence but not in QALY gained i.e. if society is willing to pay a …
There is a link between the pregnancy and its long-term influence on health and susceptibility to future chronic disease both in moth …
Review of the clinical significance of respiratory virus infections in newborn infants.
Luoto R, Jartti T, Ruuskanen O, Waris M, Lehtonen L, Heikkinen T. Luoto R, et al. Acta Paediatr. 2016 Oct;105(10):1132-9. doi: 10.1111/apa.13519. Epub 2016 Jul 31. Acta Paediatr. 2016. PMID: 27387520 Free PMC article. Review.
Respiratory viruses have been recognised as causative agents for a wide spectrum of clinical manifestations and severe respiratory compromise in neonates during birth hospitalisation. Early-life respiratory virus infections have also been shown to be associated with advers …
Respiratory viruses have been recognised as causative agents for a wide spectrum of clinical manifestations and severe respiratory compromis …
Hot flushes among aging women: A 4-year follow-up study to a randomised controlled exercise trial.
Mansikkamäki K, Nygård CH, Raitanen J, Kukkonen-Harjula K, Tomás E, Rutanen R, Luoto R. Mansikkamäki K, et al. Among authors: luoto r. Maturitas. 2016 Jun;88:84-9. doi: 10.1016/j.maturitas.2016.03.010. Epub 2016 Mar 24. Maturitas. 2016. PMID: 27105704 Clinical Trial.
OBJECTIVES: The aim of this follow-up study was to explore the long-term effects of a 6-month trial of exercise training on hot flushes. ...
OBJECTIVES: The aim of this follow-up study was to explore the long-term effects of a 6-month trial of exercise training on hot flush …
31 results