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Ceftriaxone to PRevent pneumOnia and inflammaTion aftEr Cardiac arresT (PROTECT): study protocol for a randomized, placebo-controlled trial.
Gagnon DJ, Ryzhov SV, May MA, Riker RR, Geller B, May TL, Bockian S, deKay JT, Eldridge A, Van der Kloot T, Lerwick P, Lord C, Lucas FL, Mailloux P, McCrum B, Searight M, Wirth J, Zuckerman J, Sawyer D, Seder DB. Gagnon DJ, et al. Among authors: lucas fl. Trials. 2022 Mar 4;23(1):197. doi: 10.1186/s13063-022-06127-w. Trials. 2022. PMID: 35246202 Free PMC article.
DISCUSSION: The PROTECT trial is novel in its (1) inclusion of OHCA survivors regardless of initial heart rhythm, (2) use of a low-risk antibiotic available in the USA that has not previously been tested after OHCA, (3) inclusion of anti-inflammatory effects of ceftriaxone as a n …
DISCUSSION: The PROTECT trial is novel in its (1) inclusion of OHCA survivors regardless of initial heart rhythm, (2) use of a low-risk anti …
Impact of geography and travel distance on outcomes in epithelial ovarian cancer: a national cancer database analysis.
Daruvala A, Lucas FL, Sammon J, Darus C, Bradford L. Daruvala A, et al. Among authors: lucas fl. Int J Gynecol Cancer. 2021 Feb;31(2):209-214. doi: 10.1136/ijgc-2020-001807. Epub 2020 Nov 19. Int J Gynecol Cancer. 2021. PMID: 33214215
A total of 105 529 patients were available for survival analysis, and survival curves significantly differed between distance strata (p<0.0001). The adjusted regression models demonstrated increased long-term mortality in patients who lived farther away from the treatin …
A total of 105 529 patients were available for survival analysis, and survival curves significantly differed between distance strata (p<0 …
Association of Beta Blocker Use With Bone Mineral Density in the Framingham Osteoporosis Study: A Cross-Sectional Study.
Lary CW, Hinton AC, Nevola KT, Shireman TI, Motyl KJ, Houseknecht KL, Lucas FL, Hallen S, Zullo AR, Berry SD, Kiel DP. Lary CW, et al. Among authors: lucas fl. JBMR Plus. 2020 Jul 30;4(9):e10388. doi: 10.1002/jbm4.10388. eCollection 2020 Sep. JBMR Plus. 2020. PMID: 32995691 Free PMC article.
We modeled dose in categories (no BB use, low-dose, high-dose) and as a continuous variable and found an increasing dose response that levels off at higher doses. Finally, associations were similar for short-term versus long-term (4 years versus >4 years) use. In …
We modeled dose in categories (no BB use, low-dose, high-dose) and as a continuous variable and found an increasing dose response that level …
Survey of Neonatal Intensive Care Unit Nurse Attitudes Toward Therapeutic Hypothermia Treatment.
Craig A, James C, Bainter J, Lucas FL, Evans S, Glazer J. Craig A, et al. Among authors: lucas fl. Adv Neonatal Care. 2017 Apr;17(2):123-130. doi: 10.1097/ANC.0000000000000339. Adv Neonatal Care. 2017. PMID: 27759568
Overwhelming similarities between the urban and rural institutions were found with NICU nurses expressing understanding of the indications for initiating TH, agreement that TH improves long-term outcomes and that the benefits of TH outweigh the risks. Nurses at the urban i …
Overwhelming similarities between the urban and rural institutions were found with NICU nurses expressing understanding of the indications f …
Survival after open versus endovascular thoracic aortic aneurysm repair in an observational study of the Medicare population.
Goodney PP, Travis L, Lucas FL, Fillinger MF, Goodman DC, Cronenwett JL, Stone DH. Goodney PP, et al. Among authors: lucas fl. Circulation. 2011 Dec 13;124(24):2661-9. doi: 10.1161/CIRCULATIONAHA.111.033944. Epub 2011 Nov 21. Circulation. 2011. PMID: 22104552 Free PMC article.
BACKGROUND: The goal of this study was to describe short- and long-term survival of patients with descending thoracic aortic aneurysms (TAAs) after open and endovascular repair (TEVAR). ...CONCLUSIONS: Although perioperative mortality is lower with TEVAR, Medicare patients …
BACKGROUND: The goal of this study was to describe short- and long-term survival of patients with descending thoracic aortic aneurysm …
Characteristics of new cardiac surgery programs in the United States: mitigating the learning curve.
Haskins AE, Siewers AE, Malenka DJ, Wennberg DE, Lucas FL. Haskins AE, et al. Among authors: lucas fl. Am Heart J. 2010 May;159(5):919-25. doi: 10.1016/j.ahj.2010.02.015. Am Heart J. 2010. PMID: 20435206
We compared patient, procedure, and physician characteristics and short-term mortality at established cardiac surgery programs, new programs in general hospitals, and new specialty cardiac hospitals. ...New specialty hospitals had high CABG volume from inception, similar v …
We compared patient, procedure, and physician characteristics and short-term mortality at established cardiac surgery programs, new p …
Predicting hospital mortality, length of stay, and transfer to long-term care for injured patients.
Clark DE, Lucas FL, Ryan LM. Clark DE, et al. Among authors: lucas fl. J Trauma. 2007 Mar;62(3):592-600. doi: 10.1097/01.ta.0000257239.15436.29. J Trauma. 2007. PMID: 17414333
BACKGROUND: Using hospital length of stay (LOS) to measure trauma care efficiency is complicated by short LOS resulting from early mortality or transfer to long-term care (LTC). METHODS: Records from the 1999 to 2003 National Trauma Data Bank were used to create a multista …
BACKGROUND: Using hospital length of stay (LOS) to measure trauma care efficiency is complicated by short LOS resulting from early mortality …
Long-term outcomes of regional variations in intensity of invasive vs medical management of Medicare Patients with acute myocardial infarction.
Stukel TA, Lucas FL, Wennberg DE. Stukel TA, et al. Among authors: lucas fl. JAMA. 2005 Mar 16;293(11):1329-37. doi: 10.1001/jama.293.11.1329. JAMA. 2005. PMID: 15769966 Free PMC article.
OBJECTIVES: To evaluate patient clinical characteristics associated with receiving more intensive treatment; and to assess whether AMI patients residing in regions with more intensive invasive treatment and management strategies have better long-term survival than those re …
OBJECTIVES: To evaluate patient clinical characteristics associated with receiving more intensive treatment; and to assess whether AMI patie …
Injuries among older Americans with and without Medicare.
Clark DE, DeLorenzo MA, Lucas FL, Wennberg DE. Clark DE, et al. Among authors: lucas fl. Am J Public Health. 2005 Feb;95(2):273-8. doi: 10.2105/AJPH.2003.036871. Am J Public Health. 2005. PMID: 15671464 Free PMC article.
Injured patients without Medicare or health maintenance organization coverage were younger, less likely to have hip fractures, and more likely to have head or chest injuries. Mortality and discharge to long-term care were not significantly affected by insurance coverage, a …
Injured patients without Medicare or health maintenance organization coverage were younger, less likely to have hip fractures, and more like …
Epidemiology and short-term outcomes of injured medicare patients.
Clark DE, DeLorenzo MA, Lucas FL, Wennberg DE. Clark DE, et al. Among authors: lucas fl. J Am Geriatr Soc. 2004 Dec;52(12):2023-30. doi: 10.1111/j.1532-5415.2004.52560.x. J Am Geriatr Soc. 2004. PMID: 15571537
OBJECTIVES: To describe characteristics and short-term outcomes of Medicare patients hospitalized after injuries in 1999. ...
OBJECTIVES: To describe characteristics and short-term outcomes of Medicare patients hospitalized after injuries in 1999. ...