Organic cation transporter 2 controls brain norepinephrine and serotonin clearance and antidepressant response.
Bacq A, Balasse L, Biala G, Guiard B, Gardier AM, Schinkel A, Louis F, Vialou V, Martres MP, Chevarin C, Hamon M, Giros B, Gautron S.
Bacq A, et al. Among authors: louis f.
Mol Psychiatry. 2012 Sep;17(9):926-39. doi: 10.1038/mp.2011.87. Epub 2011 Jul 19.
Mol Psychiatry. 2012.
PMID: 21769100
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OCT2(-/-) mice displayed an altered sensitivity to acute treatments with NE- and/or 5-HT-selective transport blockers in the forced-swim test. Moreover, the mutant mice were insensitive to long-term venlafaxine treatment in a more realistic, corticosterone-induced, chronic …
OCT2(-/-) mice displayed an altered sensitivity to acute treatments with NE- and/or 5-HT-selective transport blockers in the forced-swim tes …