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Modulation of endogenous antioxidant activity by resveratrol and exercise in mouse liver is age dependent.
Tung BT, Rodríguez-Bies E, Ballesteros-Simarro M, Motilva V, Navas P, López-Lluch G. Tung BT, et al. Among authors: lopez lluch g. J Gerontol A Biol Sci Med Sci. 2014 Apr;69(4):398-409. doi: 10.1093/gerona/glt102. Epub 2013 Jul 16. J Gerontol A Biol Sci Med Sci. 2014. PMID: 23861386
Our results indicate that RSV and exercise revert the effect of aging in liver of old animals maintaining higher antioxidant activities and decreasing oxidative damage. Short-term interventions are enough to produce beneficial effects of RSV or exercise at later ages....
Our results indicate that RSV and exercise revert the effect of aging in liver of old animals maintaining higher antioxidant activities and …
Caloric restriction increases learning consolidation and facilitates synaptic plasticity through mechanisms dependent on NR2B subunits of the NMDA receptor.
Fontán-Lozano A, Sáez-Cassanelli JL, Inda MC, de los Santos-Arteaga M, Sierra-Domínguez SA, López-Lluch G, Delgado-García JM, Carrión AM. Fontán-Lozano A, et al. Among authors: lopez lluch g. J Neurosci. 2007 Sep 19;27(38):10185-95. doi: 10.1523/JNEUROSCI.2757-07.2007. J Neurosci. 2007. PMID: 17881524 Free PMC article.
Here we have examined the effects of maintaining mature mice on a long-term intermittent fasting diet (L-IFD). We found that L-IFD enhances learning and consolidation processes. We also assessed the long-term changes in synaptic efficiency in these animals. L-IFD mi …
Here we have examined the effects of maintaining mature mice on a long-term intermittent fasting diet (L-IFD). We found that L-IFD en …
Dicoumarol relieves serum withdrawal-induced G0/1 blockade in HL-60 cells through a superoxide-dependent mechanism.
Bello RI, Gómez-Díaz C, López-Lluch G, Forthoffer N, Córdoba-Pedregosa MC, Navas P, Villalba JM. Bello RI, et al. Among authors: lopez lluch g. Biochem Pharmacol. 2005 Jun 1;69(11):1613-25. doi: 10.1016/j.bcp.2005.03.012. Epub 2005 Apr 18. Biochem Pharmacol. 2005. PMID: 15896341
Inhibition of G0/1 blockade was confirmed by the increase of thymidine incorporation, the phosphorylation of retinoblastoma protein, and the promotion of cell growth in long-term treatments in the absence of serum. Dicoumarol treatment increased superoxide levels, but did …
Inhibition of G0/1 blockade was confirmed by the increase of thymidine incorporation, the phosphorylation of retinoblastoma protein, and the …
Plasma membrane ubiquinone controls ceramide production and prevents cell death induced by serum withdrawal.
Barroso MP, Gómez-Díaz C, Villalba JM, Burón MI, López-Lluch G, Navas P. Barroso MP, et al. Among authors: lopez lluch g. J Bioenerg Biomembr. 1997 Jun;29(3):259-67. doi: 10.1023/a:1022462111175. J Bioenerg Biomembr. 1997. PMID: 9298711
HL-60 cells were sensitive to serum removal, and an increase of lipid peroxidation and apoptosis was observed. Long-term treatment with ethidium bromide induced the mitochondria-deficient rho(o)HL-60 cell line. ...
HL-60 cells were sensitive to serum removal, and an increase of lipid peroxidation and apoptosis was observed. Long-term treatment wi …