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Recombinant vaccinia viruses expressing GP46/M-2 protect against Leishmania infection.
McMahon-Pratt D, Rodriguez D, Rodriguez JR, Zhang Y, Manson K, Bergman C, Rivas L, Rodriguez JF, Lohman KL, Ruddle NH, et al. McMahon-Pratt D, et al. Among authors: lohman kl. Infect Immun. 1993 Aug;61(8):3351-9. doi: 10.1128/iai.61.8.3351-3359.1993. Infect Immun. 1993. PMID: 8335366 Free PMC article.
The GP46/M-2 membrane glycoprotein has been demonstrated in a murine model system to elicit a protective immune response against infection with Leishmania amazonensis; in highly susceptible BALB/c mice, immunization leads to significant protection against infection. In the presen …
The GP46/M-2 membrane glycoprotein has been demonstrated in a murine model system to elicit a protective immune response against infection w …