[Detection rate and clinical significance of regions of homozygosity in prenatal genetic diagnosis].
Zhu LF, Zhang HM, Mai LH, Sun XF, Liu WQ.
Zhu LF, et al. Among authors: liu wq.
Zhonghua Fu Chan Ke Za Zhi. 2022 Apr 25;57(4):271-277. doi: 10.3760/cma.j.cn112141-20210820-00455.
Zhonghua Fu Chan Ke Za Zhi. 2022.
PMID: 35484659
Chinese.
Among them, 25 cases (64%, 25/39) were detected only on single chromosome, and chromosome 11 had the highest detection rate, suggesting the risk of uniparental disomy; fourteen cases (36%,14/39) were detected on multiple chromosomes, most commonly on chromosomes 11, 1, 3, 4 and 8 …
Among them, 25 cases (64%, 25/39) were detected only on single chromosome, and chromosome 11 had the highest detection rate, suggesting the …