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Runx1-R188Q germ line mutation induces inflammation and predisposition to hematologic malignancies in mice.
Ahmad MH, Hegde M, Wong WJ, Mohammadhosseini M, Garrett L, Carrascoso A, Issac N, Ebert B, Silva JC, Pihan G, Zhu LJ, Wolfe SA, Agarwal A, Liu PP, Castilla LH. Ahmad MH, et al. Among authors: liu pp. Blood Adv. 2023 Dec 12;7(23):7304-7318. doi: 10.1182/bloodadvances.2023010398. Blood Adv. 2023. PMID: 37756546 Free PMC article.
The DNA-damage response activity of Runx1R188Q/+ hematopoietic progenitor cells was defective in vitro, suggesting that Runx1R188Q may promote genomic instability. The differentiation of long-term repopulating HSCs was reduced in Runx1R188Q/+ recipient mice. ...
The DNA-damage response activity of Runx1R188Q/+ hematopoietic progenitor cells was defective in vitro, suggesting that Runx1R188Q may promo …
N-acetylcysteine promotes the proliferation of porcine adipose-derived stem cells during in vitro long-term expansion for cultured meat production.
Song WJ, Liu PP, Meng ZQ, Jie Ding S, Xia Li H. Song WJ, et al. Among authors: liu pp. Food Res Int. 2023 Apr;166:112606. doi: 10.1016/j.foodres.2023.112606. Epub 2023 Feb 16. Food Res Int. 2023. PMID: 36914351
Subsequently, RNA sequencing (RNA-seq) was performed for P3 and P9 ADSCs and found that PI3K-AKT pathway was up-regulated, but cell cycle and DNA repair pathway were down-regulated in P9 ADSCs. Then, N-Acetylcysteine (NAC) was added during long-term expansion and showed th …
Subsequently, RNA sequencing (RNA-seq) was performed for P3 and P9 ADSCs and found that PI3K-AKT pathway was up-regulated, but cell cycle an …
Long-Term Risks of Stroke in Patients With Type A Aortic Dissection: A Nationwide Cohort Study.
Hsu JY, Liu PP, Liu AB, Huang HK, Loh CH. Hsu JY, et al. Among authors: liu pp. J Am Heart Assoc. 2022 Nov 15;11(22):e027178. doi: 10.1161/JAHA.122.027178. Epub 2022 Nov 3. J Am Heart Assoc. 2022. PMID: 36326053 Free PMC article.
Background Patients with type A aortic dissection (TAAD) have a high short-term risk of stroke. However, whether patients with TAAD have an increased long-term risk of stroke is still undetermined, and our study aims to address this knowledge gap. ...Conclusions Our …
Background Patients with type A aortic dissection (TAAD) have a high short-term risk of stroke. However, whether patients with TAAD h …
Neutralizing Antibodies and Cellular Immune Responses Against SARS-CoV-2 Sustained One and a Half Years After Natural Infection.
Yan LN, Liu PP, Li XG, Zhou SJ, Li H, Wang ZY, Shen F, Lu BC, Long Y, Xiao X, Wang ZD, Li D, Han HJ, Yu H, Zhou SH, Lv WL, Yu XJ. Yan LN, et al. Among authors: liu pp. Front Microbiol. 2022 Mar 3;12:803031. doi: 10.3389/fmicb.2021.803031. eCollection 2021. Front Microbiol. 2022. PMID: 35310397 Free PMC article.
BACKGROUND: COVID-19 has caused more than 2.6 billion infections and several million deaths since its outbreak 2 years ago. We know very little about the long-term cellular immune responses and the kinetics of neutralizing antibodies (NAbs) to SARS-CoV-2 because it has eme …
BACKGROUND: COVID-19 has caused more than 2.6 billion infections and several million deaths since its outbreak 2 years ago. We know very lit …
Phase II Study of Gemcitabine, Peg-Asparaginase, Dexamethasone and Methotrexate Regimen for Newly Diagnosed Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type: Final Analysis With Long-Term Follow-Up and Rational Research for the Combination.
Wang Y, Wang CQ, Sun P, Liu PP, Yang H, Wang HY, Rao HL, Li S, Jiang WQ, Huang JJ, Li ZM. Wang Y, et al. Among authors: liu pp. Front Oncol. 2022 Jan 24;12:796738. doi: 10.3389/fonc.2022.796738. eCollection 2022. Front Oncol. 2022. PMID: 35141162 Free PMC article.
Biomarker discovery in cardiac allograft vasculopathy using targeted aptamer proteomics.
Almufleh A, Zhang L, Mielniczuk LM, Stadnick E, Davies RA, Du Q, Rayner K, Liu PP, Chih S. Almufleh A, et al. Among authors: liu pp. Clin Transplant. 2020 Jan;34(1):e13765. doi: 10.1111/ctr.13765. Epub 2019 Dec 30. Clin Transplant. 2020. PMID: 31815308
Cardiac allograft vasculopathy (CAV) limits long-term survival after heart transplantation. Non-invasive evaluation is challenging, and currently, there is no validated biomarker for CAV diagnosis or prognostication. ...
Cardiac allograft vasculopathy (CAV) limits long-term survival after heart transplantation. Non-invasive evaluation is challenging, a …
Prediction and Management for Relapse of Type 1 Autoimmune Pancreatitis After Initial Steroid Treatment: A Long-Term Follow-up From China.
Xin L, Meng QQ, Hu LH, Lin H, Pan J, Hao L, Liu PP, Qian W, Wang LW, Li ZS. Xin L, et al. Among authors: liu pp. Pancreas. 2018 Oct;47(9):1110-1114. doi: 10.1097/MPA.0000000000001147. Pancreas. 2018. PMID: 30142120
Repeated steroid treatment with the same initial dose but longer induction and tapering duration was given to 87.2% patients with relapse and obtained response (97.1%) during a short-term follow-up (median, 19 months). CONCLUSIONS: Relapses are common in type 1 AIP after s …
Repeated steroid treatment with the same initial dose but longer induction and tapering duration was given to 87.2% patients with relapse an …
The Histone H3K27 Demethylase UTX Regulates Synaptic Plasticity and Cognitive Behaviors in Mice.
Tang GB, Zeng YQ, Liu PP, Mi TW, Zhang SF, Dai SK, Tang QY, Yang L, Xu YJ, Yan HL, Du HZ, Teng ZQ, Zhou FQ, Liu CM. Tang GB, et al. Among authors: liu pp. Front Mol Neurosci. 2017 Aug 24;10:267. doi: 10.3389/fnmol.2017.00267. eCollection 2017. Front Mol Neurosci. 2017. PMID: 28970783 Free PMC article.
Here, we observe that deletion of Utx results in increased anxiety-like behaviors and impaired spatial learning and memory in mice. Loss of Utx in the hippocampus leads to reduced long-term potentiation and amplitude of miniature excitatory postsynaptic current, aberrant d …
Here, we observe that deletion of Utx results in increased anxiety-like behaviors and impaired spatial learning and memory in mice. Loss of …
Overexpression and knockout of miR-126 both promote leukemogenesis.
Li Z, Chen P, Su R, Li Y, Hu C, Wang Y, Arnovitz S, He M, Gurbuxani S, Zuo Z, Elkahloun AG, Li S, Weng H, Huang H, Neilly MB, Wang S, Olson EN, Larson RA, Le Beau MM, Zhang J, Jiang X, Wei M, Jin J, Liu PP, Chen J. Li Z, et al. Among authors: liu pp. Blood. 2015 Oct 22;126(17):2005-15. doi: 10.1182/blood-2015-04-639062. Epub 2015 Sep 11. Blood. 2015. PMID: 26361793 Free PMC article.
In accordance with our observation that increased expression of miR-126 is associated with unfavorable survival in patients with t(8;21) acute myeloid leukemia (AML), we show that miR-126 overexpression exhibits a stronger effect on long-term survival and progression of AM …
In accordance with our observation that increased expression of miR-126 is associated with unfavorable survival in patients with t(8;21) acu …
29 results