Targeting DNMT3A-mediated oxidative phosphorylation to overcome ibrutinib resistance in mantle cell lymphoma.
Hoang NM, Liu Y, Bates PD, Heaton AR, Lopez AF, Liu P, Zhu F, Chen R, Kondapelli A, Zhang X, Selberg PE, Ngo VN, Skala MC, Capitini CM, Rui L.
Hoang NM, et al. Among authors: liu p.
Cell Rep Med. 2024 Apr 16;5(4):101484. doi: 10.1016/j.xcrm.2024.101484. Epub 2024 Mar 29.
Cell Rep Med. 2024.
PMID: 38554704
Free PMC article.
Acquired drug resistance, however, is significant and affects long-term survival of MCL patients. Here, we demonstrate that DNA methyltransferase 3A (DNMT3A) is involved in ibrutinib resistance. ...
Acquired drug resistance, however, is significant and affects long-term survival of MCL patients. Here, we demonstrate that DNA methy …