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Surgical Experience and Long-term Results of Baroreflex Activation Therapy for Heart Failure With Reduced Ejection Fraction.
Weaver FA, Abraham WT, Little WC, Butter C, Ducharme A, Halbach M, Klug D, Lovett EG, Madershahian N, Müller-Ehmsen J, Schafer JE, Senni M, Swarup V, Wachter R, Zile MR. Weaver FA, et al. Among authors: little wc. Semin Thorac Cardiovasc Surg. 2016 Summer;28(2):320-328. doi: 10.1053/j.semtcvs.2016.04.017. Epub 2016 Jun 2. Semin Thorac Cardiovasc Surg. 2016. PMID: 28043438 Free article. Clinical Trial.
The purpose of this publication is to describe the intraoperative experience along with long-term safety and efficacy of the second-generation baroreflex activation therapy (BAT) system in patients with heart failure (HF) and reduced ejection fraction HF (HFrEF). ...
The purpose of this publication is to describe the intraoperative experience along with long-term safety and efficacy of the second-g …
Target lesion revascularization after bare-metal or drug-eluting stents: clinical presentations and outcomes.
Hayes KR, Applegate RJ, Sacrinty MT, Kutcher MA, Gandhi SK, Santos RM, Little WC. Hayes KR, et al. Among authors: little wc. J Invasive Cardiol. 2010 Jun;22(6):266-70. J Invasive Cardiol. 2010. PMID: 20516505 Free article.
While DES substantially reduce TLR, little is known about the clinical syndromes accompanying DES TLR and the long-term clinical outcomes after TLR. METHODS: The clinical syndrome at the time of hospitalization when TLR was performed and subsequent clinical outcomes after …
While DES substantially reduce TLR, little is known about the clinical syndromes accompanying DES TLR and the long-term clinical outc …
A randomized double-blind trial of enalapril in older patients with heart failure and preserved ejection fraction: effects on exercise tolerance and arterial distensibility.
Kitzman DW, Hundley WG, Brubaker PH, Morgan TM, Moore JB, Stewart KP, Little WC. Kitzman DW, et al. Among authors: little wc. Circ Heart Fail. 2010 Jul;3(4):477-85. doi: 10.1161/CIRCHEARTFAILURE.109.898916. Epub 2010 Jun 1. Circ Heart Fail. 2010. PMID: 20516425 Free PMC article. Clinical Trial.
These data, combined with those from large clinical event trials, suggest that angiotensin inhibition does not substantially improve key long-term clinical outcomes in this group of patients. This finding contrasts sharply with observations in HF with reduced EF and highli …
These data, combined with those from large clinical event trials, suggest that angiotensin inhibition does not substantially improve key lon …
3-year comparison of drug-eluting versus bare-metal stents.
Applegate RJ, Sacrinty MT, Kutcher MA, Santos RM, Gandhi SK, Little WC. Applegate RJ, et al. Among authors: little wc. JACC Cardiovasc Interv. 2009 Mar;2(3):231-9. doi: 10.1016/j.jcin.2008.12.010. JACC Cardiovasc Interv. 2009. PMID: 19463431 Free article.
OBJECTIVES: The aim of this study was to compare 3-year cumulative outcomes to landmark second- and third-year outcomes with the routine use of drug-eluting stents (DES) (>75% "off-label") with a comparable group treated with bare-metal stents (BMS). BACKGROUND: Long-term …
OBJECTIVES: The aim of this study was to compare 3-year cumulative outcomes to landmark second- and third-year outcomes with the routine use …
Comparison of drug-eluting versus bare metal stents on later frequency of acute myocardial infarction and death.
Applegate RJ, Sacrinty MT, Kutcher MA, Baki TT, Gandhi SK, Santos RM, Little WC. Applegate RJ, et al. Among authors: little wc. Am J Cardiol. 2007 Feb 1;99(3):333-8. doi: 10.1016/j.amjcard.2006.08.032. Epub 2006 Dec 1. Am J Cardiol. 2007. PMID: 17261393
In conclusion, in this single-center observational study, use of DESs in consecutive unselected patients, most of whom would not have been eligible for inclusion in the randomized trials of DES versus BMS, was associated with lower AMI and death rates than in a comparable group o …
In conclusion, in this single-center observational study, use of DESs in consecutive unselected patients, most of whom would not have been e …
Late outcomes after intervention of vein grafts in diabetics with abciximab use.
Applegate RJ, Upadhya B, Little WC, Xenakis M, Gandhi SK, Baki TT, Kahl FR, Kutcher MA. Applegate RJ, et al. Among authors: little wc. Int J Cardiol. 2006 Jul 28;111(1):136-41. doi: 10.1016/j.ijcard.2005.08.010. Epub 2005 Oct 14. Int J Cardiol. 2006. PMID: 16226815
OBJECTIVES: We sought to evaluate late clinical outcomes following elective percutaneous coronary interventions for saphenous vein graft with planned abciximab use in diabetics. BACKGROUND: Diabetes adversely affects long-term outcomes after percutaneous coronary intervent …
OBJECTIVES: We sought to evaluate late clinical outcomes following elective percutaneous coronary interventions for saphenous vein graft wit …
Thrombogenic factors and recurrent coronary events.
Moss AJ, Goldstein RE, Marder VJ, Sparks CE, Oakes D, Greenberg H, Weiss HJ, Zareba W, Brown MW, Liang CS, Lichstein E, Little WC, Gillespie JA, Van Voorhees L, Krone RJ, Bodenheimer MM, Hochman J, Dwyer EM Jr, Arora R, Marcus FI, Watelet LF, Case RB. Moss AJ, et al. Among authors: little wc. Circulation. 1999 May 18;99(19):2517-22. doi: 10.1161/01.cir.99.19.2517. Circulation. 1999. PMID: 10330382
We hypothesized that the presence of blood factors that reflect enhanced thrombogenic activity would be associated with an increased risk of recurrent coronary events during long-term follow-up of patients who have recovered from myocardial infarction. ...
We hypothesized that the presence of blood factors that reflect enhanced thrombogenic activity would be associated with an increased risk of …