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Current Status on 1,4-Dihydropyridine Derivatives against Human Pathogenic Parasites.
Elso O, Liñares GG, Sülsen V. Elso O, et al. Among authors: linares gg. Curr Med Chem. 2023;30(15):1689-1711. doi: 10.2174/0929867330666221104162901. Curr Med Chem. 2023. PMID: 36336811 Review.
Usually, treatments are based on no specific drugs associated, in several cases, with long-term treatments and severe side effects. In addition, drug resistance and different strains' susceptibility are further drawbacks of the existing chemotherapy. ...
Usually, treatments are based on no specific drugs associated, in several cases, with long-term treatments and severe side effects. I …
Global Impact of the COVID-19 Pandemic on Stroke Volumes and Cerebrovascular Events: A 1-Year Follow-up.
Nguyen TN, Qureshi MM, Klein P, Yamagami H, Mikulik R, Czlonkowska A, Abdalkader M, Sedova P, Sathya A, Lo HC, Mansour OY, Vanguru HR, Lesaine E, Tsivgoulis G, Loochtan AI, Demeestere J, Uchino K, Inoa V, Goyal N, Charidimou A, Siegler JE, Yaghi S, Aguiar de Sousa D, Mohammaden MH, Haussen DC, Kristoffersen ES, Lereis VP, Scollo SD, Campbell BCV, Ma A, Thomas JO, Parsons MW, Singhal S, Slater LA, Tomazini Martins R, Enzinger C, Gattringer T, Rahman A, Bonnet T, Ligot N, De Raedt S, Lemmens R, Vanacker P, Vandervorst F, Conforto AB, Hidalgo RCT, de Oliveira Neves L, Martins RT, Mora Cuervo DL, Rebello LC, Santiago IB, Lameirinhas da Silva I, Sakelarova T, Kalpachki R, Alexiev F, Catanese L, Cora EA, Goyal M, Hill MD, Kelly ME, Khosravani H, Lavoie P, Peeling L, Pikula A, Rivera R, Chen HS, Chen Y, Huo X, Miao Z, Yang S, Bedekovic MR, Bralic M, Budincevic H, Corredor-Quintero AB, Lara-Sarabia OE, Cabal M, Tenora D, Fibrich P, Herzig R, Hlaváčová H, Hrabanovska E, Hlinovsky D, Jurak L, Kadlcikova J, Karpowicz I, Klecka L, Kovar M, Lauer D, Neumann J, Palouskova H, Reiser M, Rekova P, Rohan V, Skoda O, Škorňa M, Sobotková L, Sramek M, Zakova L, Christensen H, Drenck N, Iversen HK, Tru… See abstract for full author list ➔ Nguyen TN, et al. Among authors: linares g. Neurology. 2023 Jan 24;100(4):e408-e421. doi: 10.1212/WNL.0000000000201426. Epub 2022 Oct 18. Neurology. 2023. PMID: 36257718 Free PMC article.
BACKGROUND AND OBJECTIVES: Declines in stroke admission, IV thrombolysis (IVT), and mechanical thrombectomy volumes were reported during the first wave of the COVID-19 pandemic. There is a paucity of data on the longer-term effect of the pandemic on stroke volumes over the …
BACKGROUND AND OBJECTIVES: Declines in stroke admission, IV thrombolysis (IVT), and mechanical thrombectomy volumes were reported during the …
The mood stabilizer lithium potentiates the antidepressant-like effects and ameliorates oxidative stress induced by acute ketamine in a mouse model of stress.
Chiu CT, Scheuing L, Liu G, Liao HM, Linares GR, Lin D, Chuang DM. Chiu CT, et al. Among authors: linares gr. Int J Neuropsychopharmacol. 2014 Dec 28;18(6):pyu102. doi: 10.1093/ijnp/pyu102. Int J Neuropsychopharmacol. 2014. PMID: 25548109 Free PMC article.
Here, we used a mouse stress model to investigate whether adjunct lithium treatment would potentiate ketamine's antidepressant-like effects. METHODS: Mice received chronic restraint stress and long-term pre- or postketamine lithium treatment in drinking water. The effects …
Here, we used a mouse stress model to investigate whether adjunct lithium treatment would potentiate ketamine's antidepressant-like effects. …
Acute cervical myelopathy due to presumed fibrocartilaginous embolism: a case report and systematic review of the literature.
Cuello JP, Ortega-Gutierrez S, Linares G, Agarwal S, Cunningham A, Mohr JP, Mayer SA, Marshall RS, Claassen J, Badjatia N, Elkind MS, Lee K. Cuello JP, et al. Among authors: linares g. J Spinal Disord Tech. 2014 Dec;27(8):E276-81. doi: 10.1097/BSD.0000000000000115. J Spinal Disord Tech. 2014. PMID: 24901879 Review.
DATA SOURCES AND EXTRACTION: Two computerized literature searches (MEDLINE-Pubmed, EMBASE, the Cochrane Library) were performed. The search term used was "Fibrocartilaginous embolism." No language restrictions were applied. ...
DATA SOURCES AND EXTRACTION: Two computerized literature searches (MEDLINE-Pubmed, EMBASE, the Cochrane Library) were performed. The search …
Glutaredoxin 5 regulates osteoblast apoptosis by protecting against oxidative stress.
Linares GR, Xing W, Govoni KE, Chen ST, Mohan S. Linares GR, et al. Bone. 2009 May;44(5):795-804. doi: 10.1016/j.bone.2009.01.003. Epub 2009 Jan 14. Bone. 2009. PMID: 19442627 Free PMC article.
Since reduced formation of Fe-S cluster would lead to increased level of free iron, a competitive inhibitor of manganese superoxide dismutase (MnSOD), we measured MnSOD activity in Grx5 deficient osteoblasts and found MnSOD activity was significantly reduced. The consequence of l …
Since reduced formation of Fe-S cluster would lead to increased level of free iron, a competitive inhibitor of manganese superoxide dismutas …
Progresses in the field of drug design to combat tropical protozoan parasitic diseases.
Liñares GE, Ravaschino EL, Rodriguez JB. Liñares GE, et al. Curr Med Chem. 2006;13(3):335-60. doi: 10.2174/092986706775476043. Curr Med Chem. 2006. PMID: 16475941 Review.
It is based on old and fairly not specific drugs associated, in several cases, with long-term treatments and severe side effects. Drug resistance and different strains susceptibility are further drawbacks of the existing chemotherapy. ...
It is based on old and fairly not specific drugs associated, in several cases, with long-term treatments and severe side effects. Dru …
Cytogenetic abnormalities in thyroid adenomas.
Antonini P, Vénuat AM, Linares G, Caillou B, Schlumberger M, Travagli JP, Berger R, Parmentier C. Antonini P, et al. Among authors: linares g. Cancer Genet Cytogenet. 1991 Apr;52(2):157-64. doi: 10.1016/0165-4608(91)90458-7. Cancer Genet Cytogenet. 1991. PMID: 2021917
Cytogenetic investigations using short-term cultures are reported in six thyroid adenomas. Clonal and nonclonal numerical chromosomal changes were present in two tumors. ...
Cytogenetic investigations using short-term cultures are reported in six thyroid adenomas. Clonal and nonclonal numerical chromosomal …