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Oral Aspirin/ketamine versus oral ketamine for emergency department patients with acute musculoskeletal pain.
Gerges L, Fassassi C, Barberan C, Correa Bravo S, Davis A, Drapkin J, Likourezos A, Silver M, Hossain R, Niceforo P, Gohel A, Motov S. Gerges L, et al. Among authors: likourezos a. Am J Emerg Med. 2022 Aug;58:298-304. doi: 10.1016/j.ajem.2022.05.026. Epub 2022 May 19. Am J Emerg Med. 2022. PMID: 35777275 Clinical Trial.
CONCLUSION: The administration of an oral combination of VTS-Aspirin and ketamine resulted in less analgesia compared to oral ketamine alone, for the short-term treatment of moderate to severe acute musculoskeletal pain in the ED. ...
CONCLUSION: The administration of an oral combination of VTS-Aspirin and ketamine resulted in less analgesia compared to oral ketamine alone …
Analgesic Efficacy of Oral Aspirin/Ketamine Combination for Management of Acute Musculoskeletal Pain in the Emergency Department - A Proof of Concept Pilot Study.
Davis A, Fassassi C, Dove D, Drapkin J, Likourezos A, Gohel A, Favale P, Hossain R, Butt M, Gerges L, Motov S. Davis A, et al. Among authors: likourezos a. J Emerg Med. 2022 Jun;62(6):750-759. doi: 10.1016/j.jemermed.2022.01.029. Epub 2022 May 24. J Emerg Med. 2022. PMID: 35624056
BACKGROUND: Musculoskeletal pain (MSK) affects one out of three adults and is the most common source of significant long-term pain, physical disability, and under-treatment in the emergency department (ED). ...
BACKGROUND: Musculoskeletal pain (MSK) affects one out of three adults and is the most common source of significant long-term pain, p …
Comparison of Nebulized Ketamine at Three Different Dosing Regimens for Treating Painful Conditions in the Emergency Department: A Prospective, Randomized, Double-Blind Clinical Trial.
Dove D, Fassassi C, Davis A, Drapkin J, Butt M, Hossain R, Kabariti S, Likourezos A, Gohel A, Favale P, Silver M, Marshall J, Motov S. Dove D, et al. Among authors: likourezos a. Ann Emerg Med. 2021 Dec;78(6):779-787. doi: 10.1016/j.annemergmed.2021.04.031. Epub 2021 Jul 3. Ann Emerg Med. 2021. PMID: 34226073 Clinical Trial.
CONCLUSION: We found no difference between all 3 doses of ketamine administered through breath-actuated nebulizer for short-term treatment of moderate to severe pain in the emergency department....
CONCLUSION: We found no difference between all 3 doses of ketamine administered through breath-actuated nebulizer for short-term trea …
Analgesic efficacy of morphine sulfate immediate release vs. oxycodone/acetaminophen for acute pain in the emergency department.
Fassassi C, Dove D, Davis A, Butt M, Masoudi A, Drapkin J, Gohel A, Silver M, Likourezos A, Motov S. Fassassi C, et al. Among authors: likourezos a. Am J Emerg Med. 2021 Aug;46:579-584. doi: 10.1016/j.ajem.2020.11.034. Epub 2020 Nov 20. Am J Emerg Med. 2021. PMID: 33341323
CONCLUSION: MSIR provides similar analgesic efficacy as Percocet for short-term pain relief in the ED, similar rates of nausea/vomiting, and lower rates of likeability of the drug....
CONCLUSION: MSIR provides similar analgesic efficacy as Percocet for short-term pain relief in the ED, similar rates of nausea/vomiti …
Comparison of Oral Ibuprofen and Acetaminophen with Either Analgesic Alone for Pediatric Emergency Department Patients with Acute Pain.
Motov S, Butt M, Masoudi A, Palacios W, Fassassi C, Drapkin J, Likourezos A, Hossain R, Brady J, Rothberger N, Flom P, Zerzan J, Marshall J. Motov S, et al. Among authors: likourezos a. J Emerg Med. 2020 May;58(5):725-732. doi: 10.1016/j.jemermed.2020.02.010. Epub 2020 Apr 1. J Emerg Med. 2020. PMID: 32247660 Clinical Trial.
CONCLUSIONS: We found similar analgesic efficacy of oral ibuprofen and acetaminophen in comparison with each analgesic alone for short-term treatment of acute pain in the pediatric ED, but the trial was underpowered to demonstrate the analgesic superiority of the combinati …
CONCLUSIONS: We found similar analgesic efficacy of oral ibuprofen and acetaminophen in comparison with each analgesic alone for short-te …
Comparison of Oral Ibuprofen at Three Single-Dose Regimens for Treating Acute Pain in the Emergency Department: A Randomized Controlled Trial.
Motov S, Masoudi A, Drapkin J, Sotomayor C, Kim S, Butt M, Likourezos A, Fassassi C, Hossain R, Brady J, Rothberger N, Flom P, Marshall J. Motov S, et al. Among authors: likourezos a. Ann Emerg Med. 2019 Oct;74(4):530-537. doi: 10.1016/j.annemergmed.2019.05.037. Epub 2019 Aug 2. Ann Emerg Med. 2019. PMID: 31383385 Clinical Trial.
CONCLUSION: Oral ibuprofen administered at doses of 400, 600, and 800 mg has similar analgesic efficacy for short-term pain relief in adult patients presenting to the ED with acute pain....
CONCLUSION: Oral ibuprofen administered at doses of 400, 600, and 800 mg has similar analgesic efficacy for short-term pain relief in …
Intravenous subdissociative-dose ketamine versus morphine for acute geriatric pain in the Emergency Department: A randomized controlled trial.
Motov S, Mann S, Drapkin J, Butt M, Likourezos A, Yetter E, Brady J, Rothberger N, Gohel A, Flom P, Mai M, Fromm C, Marshall J. Motov S, et al. Among authors: likourezos a. Am J Emerg Med. 2019 Feb;37(2):220-227. doi: 10.1016/j.ajem.2018.05.030. Epub 2018 May 16. Am J Emerg Med. 2019. PMID: 29807629 Clinical Trial.
CONCLUSION: SDK administered at 0.3 mg/kg over 15 min provides analgesic efficacy comparable to morphine for short-term treatment of acute pain in the geriatric ED patients but results in higher rates of psychoperceptual adverse effects. ...
CONCLUSION: SDK administered at 0.3 mg/kg over 15 min provides analgesic efficacy comparable to morphine for short-term treatment of …
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
Motov S, Rockoff B, Cohen V, Pushkar I, Likourezos A, McKay C, Soleyman-Zomalan E, Homel P, Terentiev V, Fromm C. Motov S, et al. Among authors: likourezos a. Ann Emerg Med. 2015 Sep;66(3):222-229.e1. doi: 10.1016/j.annemergmed.2015.03.004. Epub 2015 Mar 26. Ann Emerg Med. 2015. PMID: 25817884 Clinical Trial.
CONCLUSION: Subdissociative intravenous ketamine administered at 0.3 mg/kg provides analgesic effectiveness and apparent safety comparable to that of intravenous morphine for short-term treatment of acute pain in the ED....
CONCLUSION: Subdissociative intravenous ketamine administered at 0.3 mg/kg provides analgesic effectiveness and apparent safety comparable t …
Surrogate decision makers' attitudes towards tube feeding in the nursing home.
Somogyi-Zalud E, Likourezos A, Chichin E, Olson E. Somogyi-Zalud E, et al. Among authors: likourezos a. Arch Gerontol Geriatr. 2001 Mar;32(2):101-111. doi: 10.1016/s0167-4943(01)00080-2. Arch Gerontol Geriatr. 2001. PMID: 11313101
In the nursing home, a widely accepted medical practice is to recommend the initiation of long term tube feeding in residents with eating difficulties. However, frequently the nursing home resident has dementia, lacks decision-making capacity, and has no advance directives …
In the nursing home, a widely accepted medical practice is to recommend the initiation of long term tube feeding in residents with ea …