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1986 1
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2003 2
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49 results

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Page 1
A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). CAPRIE Steering Committee.
CAPRIE Steering Committee. CAPRIE Steering Committee. Lancet. 1996 Nov 16;348(9038):1329-39. doi: 10.1016/s0140-6736(96)09457-3. Lancet. 1996. PMID: 8918275 Clinical Trial.
BACKGROUND: Many clinical trials have evaluated the benefit of long-term use of antiplatelet drugs in reducing the risk of clinical thrombotic events. ...There were ten (0.10%) patients in the clopidogrel group with significant reductions in neutrophils (< 1.2 x 10(9)/L …
BACKGROUND: Many clinical trials have evaluated the benefit of long-term use of antiplatelet drugs in reducing the risk of clinical t …
Patent Foramen Ovale Closure or Anticoagulation vs. Antiplatelets after Stroke.
Mas JL, Derumeaux G, Guillon B, Massardier E, Hosseini H, Mechtouff L, Arquizan C, Béjot Y, Vuillier F, Detante O, Guidoux C, Canaple S, Vaduva C, Dequatre-Ponchelle N, Sibon I, Garnier P, Ferrier A, Timsit S, Robinet-Borgomano E, Sablot D, Lacour JC, Zuber M, Favrole P, Pinel JF, Apoil M, Reiner P, Lefebvre C, Guérin P, Piot C, Rossi R, Dubois-Randé JL, Eicher JC, Meneveau N, Lusson JR, Bertrand B, Schleich JM, Godart F, Thambo JB, Leborgne L, Michel P, Pierard L, Turc G, Barthelet M, Charles-Nelson A, Weimar C, Moulin T, Juliard JM, Chatellier G; CLOSE Investigators. Mas JL, et al. N Engl J Med. 2017 Sep 14;377(11):1011-1021. doi: 10.1056/NEJMoa1705915. N Engl J Med. 2017. PMID: 28902593 Free article. Clinical Trial.
METHODS: In a multicenter, randomized, open-label trial, we assigned, in a 1:1:1 ratio, patients 16 to 60 years of age who had had a recent stroke attributed to PFO, with an associated atrial septal aneurysm or large interatrial shunt, to transcatheter PFO closure plus long-te …
METHODS: In a multicenter, randomized, open-label trial, we assigned, in a 1:1:1 ratio, patients 16 to 60 years of age who had had a recent …
Early-onset delirium after spontaneous intracerebral hemorrhage.
Marrama F, Kyheng M, Pasi M, Pierre Rutgers M, Moulin S, Diomedi M, Leys D, Cordonnier C, Hénon H, Casolla B. Marrama F, et al. Among authors: leys d. Int J Stroke. 2022 Oct;17(9):1030-1038. doi: 10.1177/17474930211059636. Epub 2021 Dec 7. Int J Stroke. 2022. PMID: 34875917
OBJECTIVE: This study aimed at identifying the incidence, predictors, and impact on long-term mortality and dementia of early-onset delirium in a cohort of patients with spontaneous intracerebral hemorrhage. ...We used a multivariable Fine-Gray model to identify baseline p …
OBJECTIVE: This study aimed at identifying the incidence, predictors, and impact on long-term mortality and dementia of early-onset d …
Long-term anxiety in spontaneous intracerebral hemorrhage survivors.
Scopelliti G, Casolla B, Boulouis G, Kuchcinski G, Moulin S, Leys D, Hénon H, Cordonnier C, Pasi M. Scopelliti G, et al. Among authors: leys d. Int J Stroke. 2022 Dec;17(10):1093-1099. doi: 10.1177/17474930221085443. Epub 2022 Mar 29. Int J Stroke. 2022. PMID: 35187993
BACKGROUND: Although anxiety is common in several neurological conditions, it has been poorly investigated after spontaneous intracerebral hemorrhage (ICH). AIMS: In consecutive ICH survivors, we assessed the long-term prevalence of anxiety and its clinical and radiologica …
BACKGROUND: Although anxiety is common in several neurological conditions, it has been poorly investigated after spontaneous intracerebral h …
Long-term mortality in survivors of spontaneous intracerebral hemorrhage.
Pasi M, Casolla B, Kyheng M, Boulouis G, Kuchcinski G, Moulin S, Labreuche J, Hénon H, Cordonnier C, Leys D. Pasi M, et al. Among authors: leys d. Int J Stroke. 2021 Jun;16(4):448-455. doi: 10.1177/1747493020954946. Epub 2020 Sep 3. Int J Stroke. 2021. PMID: 32883189
BACKGROUND: Factors associated with long-term mortality after spontaneous intracerebral hemorrhage (ICH) have been poorly investigated. ...Among MRI markers of chronic brain injury, only cerebral atrophy is associated with long-term mortality....
BACKGROUND: Factors associated with long-term mortality after spontaneous intracerebral hemorrhage (ICH) have been poorly investigate …
Long-term neuropsychiatric symptoms in spontaneous intracerebral haemorrhage survivors.
Scopelliti G, Casolla B, Boulouis G, Kuchcinski G, Moulin S, Leys D, Henon H, Cordonnier C, Pasi M. Scopelliti G, et al. Among authors: leys d. J Neurol Neurosurg Psychiatry. 2022 Mar;93(3):232-237. doi: 10.1136/jnnp-2021-327557. Epub 2021 Nov 2. J Neurol Neurosurg Psychiatry. 2022. PMID: 34728587
We performed NP evaluation using the Neuropsychiatric Inventory Questionnaire. Patients underwent long-term clinical follow-up after ICH (median follow-up time 7.2 years, IQR 4.8-8.2). ...Distinctive NP profile might be associated to cognitive status and inform on long- …
We performed NP evaluation using the Neuropsychiatric Inventory Questionnaire. Patients underwent long-term clinical follow-up after …
Antiplatelet Therapy After Noncardioembolic Stroke.
Greving JP, Diener HC, Reitsma JB, Bath PM, Csiba L, Hacke W, Kappelle LJ, Koudstaal PJ, Leys D, Mas JL, Sacco RL, Algra A. Greving JP, et al. Among authors: leys d. Stroke. 2019 Jul;50(7):1812-1818. doi: 10.1161/STROKEAHA.118.024497. Epub 2019 Jun 10. Stroke. 2019. PMID: 31177983 Free PMC article.
Methods- We did a network meta-analysis (NMA) of data from 6 randomized trials of the effects of commonly prescribed antiplatelet agents in the long-term (3 months) secondary prevention of noncardioembolic stroke or transient ischemic attack. ...Conclusions- Results favor …
Methods- We did a network meta-analysis (NMA) of data from 6 randomized trials of the effects of commonly prescribed antiplatelet agents in …
Cervical-artery dissections: predisposing factors, diagnosis, and outcome.
Debette S, Leys D. Debette S, et al. Among authors: leys d. Lancet Neurol. 2009 Jul;8(7):668-78. doi: 10.1016/S1474-4422(09)70084-5. Lancet Neurol. 2009. PMID: 19539238 Review.
Incidence of the disorder in the general population is underestimated. Mortality and short-term recurrence rates are low but possibly also underestimated. Further research is warranted to improve our understanding of the underlying pathophysiology, to assess the long-te …
Incidence of the disorder in the general population is underestimated. Mortality and short-term recurrence rates are low but possibly …
Long-term functional decline of spontaneous intracerebral haemorrhage survivors.
Pasi M, Casolla B, Kyheng M, Boulouis G, Kuchcinski G, Moulin S, Labreuche J, Henon H, Leys D, Cordonnier C. Pasi M, et al. Among authors: leys d. J Neurol Neurosurg Psychiatry. 2021 Mar;92(3):249-254. doi: 10.1136/jnnp-2020-324741. Epub 2020 Nov 25. J Neurol Neurosurg Psychiatry. 2021. PMID: 33239438
49 results