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Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.
GBD 2021 Diseases and Injuries Collaborators. GBD 2021 Diseases and Injuries Collaborators. Lancet. 2024 Apr 15:S0140-6736(24)00757-8. doi: 10.1016/S0140-6736(24)00757-8. Online ahead of print. Lancet. 2024. PMID: 38642570
Age-standardised DALY rates due to injuries decreased globally by 24.0% (20.7-27.2) between 2010 and 2021, although improvements were not uniform across locations, ages, and sexes. Globally, HALE at birth improved slightly, from 61.3 years (58.6-63.6) in 2010 to 62.2 years …
Age-standardised DALY rates due to injuries decreased globally by 24.0% (20.7-27.2) between 2010 and 2021, although improvements were not un …
Plasma SOMAmer proteomics of postoperative delirium.
Leung JM, Rojas JC, Sands LP, Chan B, Rajbanshi B, Du Z, Du P; Perioperative Medicine Research group. Leung JM, et al. Brain Behav. 2024 Feb;14(2):e3422. doi: 10.1002/brb3.3422. Brain Behav. 2024. PMID: 38346717 Free PMC article.
BACKGROUND: Postoperative delirium is prevalent in older adults and has been shown to increase the risk of long-term cognitive decline. Plasma biomarkers to identify the risk for postoperative delirium and the risk of Alzheimer's disease and related dementias are needed. . …
BACKGROUND: Postoperative delirium is prevalent in older adults and has been shown to increase the risk of long-term cognitive declin …
Skin muscle is the initial site of viral replication for arboviral bunyavirus infection.
Schneider CA, Leung JM, Valenzuela-Leon PC, Golviznina NA, Toso EA, Bosnakovski D, Kyba M, Calvo E, Peterson KE. Schneider CA, et al. Among authors: leung jm. Nat Commun. 2024 Feb 6;15(1):1121. doi: 10.1038/s41467-024-45304-0. Nat Commun. 2024. PMID: 38321047 Free PMC article.
Surprisingly, muscle cells are resistant to virus-induced cell death, with long term low levels of virus release progressing through the Golgi apparatus. ...
Surprisingly, muscle cells are resistant to virus-induced cell death, with long term low levels of virus release progressing through …
Four year evaluation of a parent advisory group to support a research program for knowledge translation in child health.
Hartling L, Elliott SA, Mabbott A, Leung J, Shearer K, Smith C, Scott SD. Hartling L, et al. Among authors: leung j. Res Involv Engagem. 2024 Jan 28;10(1):14. doi: 10.1186/s40900-024-00547-5. Res Involv Engagem. 2024. PMID: 38281949 Free PMC article.
We applied a mixed methods approach, collecting and analyzing both quantitative (survey) and qualitative (survey/interview) data. Survey data were analyzed by term using descriptive statistics (i.e., frequencies, percentages). ...
We applied a mixed methods approach, collecting and analyzing both quantitative (survey) and qualitative (survey/interview) data. Survey dat …
Implementation of a high sensitivity cardiac troponin I assay and risk of myocardial infarction or death at five years: observational analysis of a stepped wedge, cluster randomised controlled trial.
Lee KK, Doudesis D, Ferry AV, Chapman AR, Kimenai DM, Fujisawa T, Bularga A, Lowry MTH, Taggart C, Schulberg S, Wereski R, Tuck C, Strachan FE, Newby DE, Anand A, Shah ASV, Mills NL; High-STEACS Investigators. Lee KK, et al. BMJ. 2023 Nov 27;383:e075009. doi: 10.1136/bmj-2023-075009. BMJ. 2023. PMID: 38011922 Free PMC article. Clinical Trial.
OBJECTIVE: To evaluate the impact of implementing a high sensitivity assay for cardiac troponin I on long term outcomes in patients with suspected acute coronary syndrome. ...
OBJECTIVE: To evaluate the impact of implementing a high sensitivity assay for cardiac troponin I on long term outcomes in patients w …
Changes in affective control covary with changes in mental health difficulties following affective control training (AffeCT) in adolescents.
Schweizer S, Leung JT, Trender W, Kievit R, Hampshire A, Blakemore SJ. Schweizer S, et al. Among authors: leung jt. Psychol Med. 2024 Feb;54(3):539-547. doi: 10.1017/S0033291723002167. Epub 2023 Aug 23. Psychol Med. 2024. PMID: 37609895 Free PMC article.
CONCLUSION: In conclusion, the study provides preliminary evidence that AffeCT may confer short-term preventative benefits for adolescent mental health....
CONCLUSION: In conclusion, the study provides preliminary evidence that AffeCT may confer short-term preventative benefits for adoles …
Can antimony contamination in soil undermine the ecological contributions of earthworms?
Su X, Wang X, Zhou Z, Zeng X, Wu Q, Leung JYS. Su X, et al. Among authors: leung jys. Sci Total Environ. 2023 Dec 15;904:166305. doi: 10.1016/j.scitotenv.2023.166305. Epub 2023 Aug 14. Sci Total Environ. 2023. PMID: 37586541
Since extreme Sb contamination in soil (>100 mg/kg) is rarely found in nature, we are optimistic that the health and performance of earthworms are not influenced by Sb in most circumstances, but regular monitoring of Sb in soil is recommended to ensure the integrity and functi …
Since extreme Sb contamination in soil (>100 mg/kg) is rarely found in nature, we are optimistic that the health and performance of earth …
Study protocol of the Our Futures Vaping Trial: a cluster randomised controlled trial of a school-based eHealth intervention to prevent e-cigarette use among adolescents.
Gardner LA, Rowe AL, Stockings E, Champion KE, Hides L, McBride N, Allsop S, O'Dean S, Sunderland M, Lee YY, Mihalopoulos C, Freeman B, Leung J, McRobbie H, Stapinski L, Lee N, Thornton L, Debenham J, Teesson M, Newton NC. Gardner LA, et al. Among authors: leung j. BMC Public Health. 2023 Apr 12;23(1):683. doi: 10.1186/s12889-023-15609-8. BMC Public Health. 2023. PMID: 37046211 Free PMC article.
Cost-effectiveness and the effect on primary and secondary outcomes will also be examined over the longer-term. DISCUSSION: If effective, the intervention will be readily accessible to schools via the OurFutures platform and has the potential to make substantial health and …
Cost-effectiveness and the effect on primary and secondary outcomes will also be examined over the longer-term. DISCUSSION: If effect …
Factors Influencing Parental Decision-Making Regarding Analgesia for Children with Musculoskeletal Injury-Related Pain: A Qualitative Study.
Ali S, Dworsky-Fried Z, Moir M, Bharadia M, Rajagopal M, Gouin S, Sawyer S, Pellerin S, Bourrier L, Poonai N, Stang A, Leung J, van Manen M; KidsCAN PERC Innovative Pediatric Clinical Trials No OUCH Study Team. Ali S, et al. Among authors: leung j. J Pediatr. 2023 Jul;258:113405. doi: 10.1016/j.jpeds.2023.113405. Epub 2023 Apr 4. J Pediatr. 2023. PMID: 37023945
For most parents, the desire to relieve their children's pain outweighed concerns of substance use disorder, misuse, and adverse events when making decisions about opioid analgesia for short-term use. These results can inform evidence-based family-centered approaches to co …
For most parents, the desire to relieve their children's pain outweighed concerns of substance use disorder, misuse, and adverse events when …
142 results