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Association of Traditional and Nontraditional Risk Factors in the Development of Strokes Among Young Adults by Sex and Age Group: A Retrospective Case-Control Study.
Leppert MH, Poisson SN, Scarbro S, Suresh K, Lisabeth LD, Putaala J, Schwamm LH, Daugherty SL, Bradley CJ, Burke JF, Ho PM. Leppert MH, et al. Circ Cardiovasc Qual Outcomes. 2024 Apr;17(4):e010307. doi: 10.1161/CIRCOUTCOMES.123.010307. Epub 2024 Mar 26. Circ Cardiovasc Qual Outcomes. 2024. PMID: 38529631 Free article.
The Impact of Erythropoietin on Short- and Long-Term Kidney-Related Outcomes in Neonates of Extremely Low Gestational Age. Results of a Multicenter, Double-Blind, Placebo-Controlled Randomized Clinical Trial.
Askenazi DJ, Heagerty PJ, Schmicker RH, Brophy P, Juul SE, Goldstein SL, Hingorani S; PENUT Trial Consortium. Askenazi DJ, et al. J Pediatr. 2021 May;232:65-72.e7. doi: 10.1016/j.jpeds.2021.01.031. Epub 2021 Jan 20. J Pediatr. 2021. PMID: 33484699 Free PMC article. Clinical Trial.
CONCLUSIONS: ELGANs have high rates of in-hospital AKI and kidney-related problems at 22-26 months of cGA. Recombinant erythropoietin may protect ELGANs against long-term elevated SBP but does not appear to protect from AKI, low eGFR, albuminuria, or elevated DBP at 22-26 …
CONCLUSIONS: ELGANs have high rates of in-hospital AKI and kidney-related problems at 22-26 months of cGA. Recombinant erythropoietin may pr …
Correlation Between White Matter Injury Identified by Neonatal Diffusion Tensor Imaging and Neurodevelopmental Outcomes Following Term Neonatal Asphyxia and Therapeutic Hypothermia: An Exploratory Pilot Study.
Gerner GJ, Newman EI, Burton VJ, Roman B, Cristofalo EA, Leppert M, Johnston MV, Northington FJ, Huisman TAGM, Poretti A. Gerner GJ, et al. Among authors: leppert m. J Child Neurol. 2019 Sep;34(10):556-566. doi: 10.1177/0883073819841717. Epub 2019 May 9. J Child Neurol. 2019. PMID: 31070085 Free PMC article.
The Role of Integrated Care in a Medical Home for Patients With a Fetal Alcohol Spectrum Disorder.
Turchi RM, Smith VC; COMMITTEE ON SUBSTANCE USE AND PREVENTION; COUNCIL ON CHILDREN WITH DISABILITIES. Turchi RM, et al. Pediatrics. 2018 Oct;142(4):e20182333. doi: 10.1542/peds.2018-2333. Epub 2018 Sep 10. Pediatrics. 2018. PMID: 30201625 Review.
Fetal alcohol spectrum disorder (FASD) is an umbrella term used to describe preventable birth defects and intellectual and/or developmental disabilities resulting from prenatal alcohol exposure. ...
Fetal alcohol spectrum disorder (FASD) is an umbrella term used to describe preventable birth defects and intellectual and/or …
Neurodevelopmental Outcomes in 22 Children With Microcephaly of Different Etiologies.
Gordon-Lipkin E, Gentner MB, German R, Leppert ML. Gordon-Lipkin E, et al. Among authors: leppert ml. J Child Neurol. 2017 Aug;32(9):804-809. doi: 10.1177/0883073817707301. Epub 2017 May 8. J Child Neurol. 2017. PMID: 28482742
We conclude that infants with microcephaly are at significant risk for delay across all aspects of development and for long-term disability. Postnatal etiologies of microcephaly and infants with comorbid epilepsy had worse outcomes....
We conclude that infants with microcephaly are at significant risk for delay across all aspects of development and for long-term disa …
Transfontanellar duplex brain ultrasonography resistive indices as a prognostic tool in neonatal hypoxic-ischemic encephalopathy before and after treatment with therapeutic hypothermia.
Gerner GJ, Burton VJ, Poretti A, Bosemani T, Cristofalo E, Tekes A, Seyfert D, Parkinson C, Leppert M, Allen M, Huisman TA, Northington FJ, Johnston MV. Gerner GJ, et al. Among authors: leppert m. J Perinatol. 2016 Mar;36(3):202-6. doi: 10.1038/jp.2015.169. Epub 2015 Nov 26. J Perinatol. 2016. PMID: 26609871 Free PMC article.
We compared pre- and post-cooling RI values and examined the relationships between RI values and specific long-term neurodevelopmental outcomes. STUDY DESIGN: Transfontanellar duplex brain sonography, including RI, were obtained for 28 neonates prior to cooling and for 20 …
We compared pre- and post-cooling RI values and examined the relationships between RI values and specific long-term neurodevelopmenta …
A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction.
Weiss RB, Baker TB, Cannon DS, von Niederhausern A, Dunn DM, Matsunami N, Singh NA, Baird L, Coon H, McMahon WM, Piper ME, Fiore MC, Scholand MB, Connett JE, Kanner RE, Gahring LC, Rogers SW, Hoidal JR, Leppert MF. Weiss RB, et al. Among authors: leppert mf. PLoS Genet. 2008 Jul 11;4(7):e1000125. doi: 10.1371/journal.pgen.1000125. PLoS Genet. 2008. PMID: 18618000 Free PMC article. Clinical Trial.
People who begin daily smoking at an early age are at greater risk of long-term nicotine addiction. We tested the hypothesis that associations between nicotinic acetylcholine receptor (nAChR) genetic variants and nicotine dependence assessed in adulthood will be stronger a …
People who begin daily smoking at an early age are at greater risk of long-term nicotine addiction. We tested the hypothesis that ass …
Association of adipose and red blood cell lipids with severity of dominant Stargardt macular dystrophy (STGD3) secondary to an ELOVL4 mutation.
Hubbard AF, Askew EW, Singh N, Leppert M, Bernstein PS. Hubbard AF, et al. Among authors: leppert m. Arch Ophthalmol. 2006 Feb;124(2):257-63. doi: 10.1001/archopht.124.2.257. Arch Ophthalmol. 2006. PMID: 16476896
Red blood cell membrane and adipose tissue lipids were analyzed as an indication of short-term and long-term dietary fatty acid intake. RESULTS: When adipose lipids were analyzed, there was a significant inverse relationship between phenotypic severity and the level …
Red blood cell membrane and adipose tissue lipids were analyzed as an indication of short-term and long-term dietary fatty aci …
Relationship of Ki-ras mutations in colon cancers to tumor location, stage, and survival: a population-based study.
Samowitz WS, Curtin K, Schaffer D, Robertson M, Leppert M, Slattery ML. Samowitz WS, et al. Among authors: leppert m. Cancer Epidemiol Biomarkers Prev. 2000 Nov;9(11):1193-7. Cancer Epidemiol Biomarkers Prev. 2000. PMID: 11097226
After adjusting for age and stage, the codon 13 G-->A mutation was associated with a 40% (95% confidence interval, 0.95-2.0) increase in short-term mortality from colon cancer. In conclusion, this population-based study demonstrates important relationships between Ki-ra …
After adjusting for age and stage, the codon 13 G-->A mutation was associated with a 40% (95% confidence interval, 0.95-2.0) increase in …
Congenital muscular dystrophy with rigid spine syndrome: a clinical, pathological, radiological, and genetic study.
Flanigan KM, Kerr L, Bromberg MB, Leonard C, Tsuruda J, Zhang P, Gonzalez-Gomez I, Cohn R, Campbell KP, Leppert M. Flanigan KM, et al. Among authors: leppert m. Ann Neurol. 2000 Feb;47(2):152-61. Ann Neurol. 2000. PMID: 10665485
Rigid spine syndrome is a term first proposed by Dubowitz to describe a subset of patients affected by myopathy with early spinal contractures as a prominent feature. ...
Rigid spine syndrome is a term first proposed by Dubowitz to describe a subset of patients affected by myopathy with early spinal con …
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