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Dynamic Suppression of Average Facial Structure Shapes Neural Tuning in Three Macaque Face Patches.
Koyano KW, Jones AP, McMahon DBT, Waidmann EN, Russ BE, Leopold DA. Koyano KW, et al. Among authors: leopold da. Curr Biol. 2021 Jan 11;31(1):1-12.e5. doi: 10.1016/j.cub.2020.09.070. Epub 2020 Oct 15. Curr Biol. 2021. PMID: 33065012 Free PMC article.
Control experiments confirmed that the diminished responses to low-identity faces were not due to short-term adaptation processes. We propose that the brain's neural suppression of average facial structure facilitates recognition by promoting the extraction of distinctive …
Control experiments confirmed that the diminished responses to low-identity faces were not due to short-term adaptation processes. We …
Identifying Treatments for Taste and Smell Disorders: Gaps and Opportunities.
Mainland JD, Barlow LA, Munger SD, Millar SE, Vergara MN, Jiang P, Schwob JE, Goldstein BJ, Boye SE, Martens JR, Leopold DA, Bartoshuk LM, Doty RL, Hummel T, Pinto JM, Trimmer C, Kelly C, Pribitkin EA, Reed DR. Mainland JD, et al. Among authors: leopold da. Chem Senses. 2020 Oct 9;45(7):493-502. doi: 10.1093/chemse/bjaa038. Chem Senses. 2020. PMID: 32556127 Free PMC article.
Over 12% of the US population is estimated to experience taste and smell (chemosensory) dysfunction. Yet, despite this high prevalence, long-term, effective treatments for these disorders have been largely elusive. ...Their suggestions for high-yield next steps were focuse …
Over 12% of the US population is estimated to experience taste and smell (chemosensory) dysfunction. Yet, despite this high prevalence, long …
Spatial organization of occipital white matter tracts in the common marmoset.
Kaneko T, Takemura H, Pestilli F, Silva AC, Ye FQ, Leopold DA. Kaneko T, et al. Among authors: leopold da. Brain Struct Funct. 2020 May;225(4):1313-1326. doi: 10.1007/s00429-020-02060-3. Epub 2020 Apr 6. Brain Struct Funct. 2020. PMID: 32253509 Free PMC article.
We compare several aspects of this continuous structure, which we term the VOF complex (VOF +), and neighboring fasciculi to those of macaques and humans. ...
We compare several aspects of this continuous structure, which we term the VOF complex (VOF +), and neighboring fasciculi to those of …
Temporal-prefrontal cortical network for discrimination of valuable objects in long-term memory.
Ghazizadeh A, Griggs W, Leopold DA, Hikosaka O. Ghazizadeh A, et al. Among authors: leopold da. Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):E2135-E2144. doi: 10.1073/pnas.1707695115. Epub 2018 Feb 1. Proc Natl Acad Sci U S A. 2018. PMID: 29437980 Free PMC article.
Similar long-term value-based modulation was also observed in subregions of the striatum, amygdala, and claustrum, but not in the hippocampus. ...In separate testing, free-viewing gaze behavior indicated that the monkeys retained stable long-term memory of object va …
Similar long-term value-based modulation was also observed in subregions of the striatum, amygdala, and claustrum, but not in the hip …
One month in the life of a neuron: longitudinal single-unit electrophysiology in the monkey visual system.
McMahon DB, Bondar IV, Afuwape OA, Ide DC, Leopold DA. McMahon DB, et al. Among authors: leopold da. J Neurophysiol. 2014 Oct 1;112(7):1748-62. doi: 10.1152/jn.00052.2014. Epub 2014 Jun 25. J Neurophysiol. 2014. PMID: 24966298 Free PMC article.
The microwire bundle and other implanted components were MRI compatible and thus permitted in the same animals both functional imaging and long-term recording from multiple neurons in deep structures within a region the approximate size of one voxel (<1 mm). The distinc …
The microwire bundle and other implanted components were MRI compatible and thus permitted in the same animals both functional imaging and l …
Perceptual memory drives learning of retinotopic biases for bistable stimuli.
Murphy AP, Leopold DA, Welchman AE. Murphy AP, et al. Among authors: leopold da. Front Psychol. 2014 Feb 3;5:60. doi: 10.3389/fpsyg.2014.00060. eCollection 2014. Front Psychol. 2014. PMID: 24550874 Free PMC article.
These phenonema have typically been regarded as independent processes, with short-term biases attributed to perceptual memory and longer-term biases described as associative learning. Here we tested for interactions between these two forms of experience-dependent pe …
These phenonema have typically been regarded as independent processes, with short-term biases attributed to perceptual memory and lon …
Olfactory cocainization is not an effective long-term treatment for phantosmia.
Leopold DA, Hornung DE. Leopold DA, et al. Chem Senses. 2013 Nov;38(9):803-6. doi: 10.1093/chemse/bjt047. Epub 2013 Oct 11. Chem Senses. 2013. PMID: 24122320
In the 1960s, Zilstorff reported olfactory distortions could be treated by the topical application of a cocaine solution to the olfactory epithelium. In evaluating this treatment, we observed no long-term benefit using cocaine on 6 patients with phantosmia. Based on our ob …
In the 1960s, Zilstorff reported olfactory distortions could be treated by the topical application of a cocaine solution to the olfactory ep …
Long-term follow-up of surgically treated phantosmia.
Leopold DA, Loehrl TA, Schwob JE. Leopold DA, et al. Arch Otolaryngol Head Neck Surg. 2002 Jun;128(6):642-7. doi: 10.1001/archotol.128.6.642. Arch Otolaryngol Head Neck Surg. 2002. PMID: 12049557