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Year Number of Results
1966 1
1990 1
1995 1
1997 1
1998 1
1999 1
2000 2
2001 1
2002 2
2003 1
2004 1
2005 1
2006 1
2007 1
2008 2
2009 1
2010 2
2011 4
2012 4
2013 5
2014 3
2015 2
2016 2
2017 1
2018 4
2019 5
2020 11
2021 2
2022 2
2023 6
2024 1

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66 results

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Page 1
Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer.
Balachandran VP, Łuksza M, Zhao JN, Makarov V, Moral JA, Remark R, Herbst B, Askan G, Bhanot U, Senbabaoglu Y, Wells DK, Cary CIO, Grbovic-Huezo O, Attiyeh M, Medina B, Zhang J, Loo J, Saglimbeni J, Abu-Akeel M, Zappasodi R, Riaz N, Smoragiewicz M, Kelley ZL, Basturk O; Australian Pancreatic Cancer Genome Initiative; Garvan Institute of Medical Research; Prince of Wales Hospital; Royal North Shore Hospital; University of Glasgow; St Vincent’s Hospital; QIMR Berghofer Medical Research Institute; University of Melbourne, Centre for Cancer Research; University of Queensland, Institute for Molecular Bioscience; Bankstown Hospital; Liverpool Hospital; Royal Prince Alfred Hospital, Chris O’Brien Lifehouse; Westmead Hospital; Fremantle Hospital; St John of God Healthcare; Royal Adelaide Hospital; Flinders Medical Centre; Envoi Pathology; Princess Alexandria Hospital; Austin Hospital; Johns Hopkins Medical Institutes; ARC-Net Centre for Applied Research on Cancer; Gönen M, Levine AJ, Allen PJ, Fearon DT, Merad M, Gnjatic S, Iacobuzio-Donahue CA, Wolchok JD, DeMatteo RP, Chan TA, Greenbaum BD, Merghoub T, Leach SD. Balachandran VP, et al. Nature. 2017 Nov 23;551(7681):512-516. doi: 10.1038/nature24462. Epub 2017 Nov 8. Nature. 2017. PMID: 29132146 Free PMC article.
T-cell immunity has been linked to the exceptional outcome of the few long-term survivors, yet the relevant antigens remain unknown. Here we use genetic, immunohistochemical and transcriptional immunoprofiling, computational biophysics, and functional assays to identify T- …
T-cell immunity has been linked to the exceptional outcome of the few long-term survivors, yet the relevant antigens remain unknown. …
Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials.
Early Breast Cancer Trialists' Collaborative Group (EBCTCG); Davies C, Godwin J, Gray R, Clarke M, Cutter D, Darby S, McGale P, Pan HC, Taylor C, Wang YC, Dowsett M, Ingle J, Peto R. Early Breast Cancer Trialists' Collaborative Group (EBCTCG), et al. Lancet. 2011 Aug 27;378(9793):771-84. doi: 10.1016/S0140-6736(11)60993-8. Epub 2011 Jul 28. Lancet. 2011. PMID: 21802721 Free PMC article.
BACKGROUND: As trials of 5 years of tamoxifen in early breast cancer mature, the relevance of hormone receptor measurements (and other patient characteristics) to long-term outcome can be assessed increasingly reliably. We report updated meta-analyses of the trials of 5 ye …
BACKGROUND: As trials of 5 years of tamoxifen in early breast cancer mature, the relevance of hormone receptor measurements (and other patie …
Is Attentional Filtering Impaired in Schizophrenia?
Luck SJ, Leonard CJ, Hahn B, Gold JM. Luck SJ, et al. Among authors: leonard cj. Schizophr Bull. 2019 Sep 11;45(5):1001-1011. doi: 10.1093/schbul/sbz045. Schizophr Bull. 2019. PMID: 31206163 Free PMC article. Review.
Management of squamous cell carcinomas of the skull-base.
Leonard CG, Padhye V, Witterick IJ. Leonard CG, et al. J Neurooncol. 2020 Dec;150(3):377-386. doi: 10.1007/s11060-020-03545-1. Epub 2020 Jun 5. J Neurooncol. 2020. PMID: 32504403 Review.
PURPOSE: The purpose of this review is to assess the recent evidence regarding the management of squamous cell carcinoma of the skull-base and to discuss the implications of these findings on clinical practice. METHOD: Free text Medline and MeSH term search of publications …
PURPOSE: The purpose of this review is to assess the recent evidence regarding the management of squamous cell carcinoma of the skull-base a …
Human cortical interneurons optimized for grafting specifically integrate, abort seizures, and display prolonged efficacy without over-inhibition.
Zhu Q, Mishra A, Park JS, Liu D, Le DT, Gonzalez SZ, Anderson-Crannage M, Park JM, Park GH, Tarbay L, Daneshvar K, Brandenburg M, Signoretti C, Zinski A, Gardner EJ, Zheng KL, Abani CP, Hu C, Beaudreault CP, Zhang XL, Stanton PK, Cho JH, Velíšek L, Velíšková J, Javed S, Leonard CS, Kim HY, Chung S. Zhu Q, et al. Among authors: leonard cs. Neuron. 2023 Mar 15;111(6):807-823.e7. doi: 10.1016/j.neuron.2022.12.014. Epub 2023 Jan 9. Neuron. 2023. PMID: 36626901 Free PMC article.
However, a safe and reliable clinical translation requires a mechanistic understanding of graft function, as well as the assurance of long-term efficacy and safety. By employing hPSC-derived chemically matured migratory cINs in two models of epilepsy, we demonstrate lastin …
However, a safe and reliable clinical translation requires a mechanistic understanding of graft function, as well as the assurance of long- …
Mechanisms underlying anomia treatment outcomes.
Simic T, Chambers C, Bitan T, Stewart S, Goldberg D, Laird L, Leonard C, Rochon E. Simic T, et al. Among authors: leonard c. J Commun Disord. 2020 Nov-Dec;88:106048. doi: 10.1016/j.jcomdis.2020.106048. Epub 2020 Sep 29. J Commun Disord. 2020. PMID: 33059274
Treatments for anomia have demonstrated short- and long-term efficacy. However, individual outcomes can be variable, and evidence for treatment generalization is limited. ...Group analyses indicate significant improvements in naming treated compared to untreated words, at …
Treatments for anomia have demonstrated short- and long-term efficacy. However, individual outcomes can be variable, and evidence for …
Comparative safety of antimuscarinics versus mirabegron for overactive bladder in Parkinson disease.
Abraham DS, Pham Nguyen TP, Newcomb CW, Gray SL, Hennessy S, Leonard CE, Liu Q, Weintraub D, Willis AW. Abraham DS, et al. Among authors: leonard ce. Parkinsonism Relat Disord. 2023 Oct;115:105822. doi: 10.1016/j.parkreldis.2023.105822. Epub 2023 Sep 4. Parkinsonism Relat Disord. 2023. PMID: 37713748
CONCLUSIONS: Among persons with PD, anticholinergic initiation was associated with a higher risk of acute care encounters compared with beta-3 agonist initiation. The long-term safety of anticholinergic vs. beta-3 agonist therapy in the PD population should be evaluated in …
CONCLUSIONS: Among persons with PD, anticholinergic initiation was associated with a higher risk of acute care encounters compared with beta …
Isolating biomarkers for symptomatic states: considering symptom-substrate chronometry.
Treadway MT, Leonard CV. Treadway MT, et al. Among authors: leonard cv. Mol Psychiatry. 2016 Sep;21(9):1180-7. doi: 10.1038/mp.2016.83. Epub 2016 May 31. Mol Psychiatry. 2016. PMID: 27240533 Free PMC article. Review.
Although prior reviews have attributed this state of affairs to diagnostic heterogeneity, symptom comorbidity and phenotypic complexity, little attention has been paid to the implications of intra-individual symptom dynamics and inter-relatedness for biomarker study designs. In t …
Although prior reviews have attributed this state of affairs to diagnostic heterogeneity, symptom comorbidity and phenotypic complexity, lit …
The Hyperfocusing Hypothesis: A New Account of Cognitive Dysfunction in Schizophrenia.
Luck SJ, Hahn B, Leonard CJ, Gold JM. Luck SJ, et al. Among authors: leonard cj. Schizophr Bull. 2019 Sep 11;45(5):991-1000. doi: 10.1093/schbul/sbz063. Schizophr Bull. 2019. PMID: 31317191 Free PMC article. Review.
Impairments in basic cognitive processes such as attention and working memory are commonly observed in people with schizophrenia and are predictive of long-term outcome. In this review, we describe a new theory-the hyperfocusing hypothesis-which provides a unified account …
Impairments in basic cognitive processes such as attention and working memory are commonly observed in people with schizophrenia and are pre …
Bisphosphonate-induced osteonecrosis of the ear canal: our experience and a review of the literature.
McCadden L, Leonard CG, Primrose WJ. McCadden L, et al. Among authors: leonard cg. J Laryngol Otol. 2018 Apr;132(4):372-374. doi: 10.1017/S0022215118000324. Epub 2018 Feb 28. J Laryngol Otol. 2018. PMID: 29486808 Review.
For such a commonly prescribed medication, the risks and side effects of bisphosphonate should be better known and long-term treatment should be avoided if possible....
For such a commonly prescribed medication, the risks and side effects of bisphosphonate should be better known and long-term treatmen …
66 results