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Multiple treatments with human embryonic stem cell-derived mesenchymal progenitor cells preserved the fertility and ovarian function of perimenopausal mice undergoing natural aging.
Shin EY, Jeong S, Lee JE, Jeong DS, Han DK, Hong SH, Lee DR. Shin EY, et al. Among authors: lee dr. Stem Cell Res Ther. 2024 Mar 3;15(1):58. doi: 10.1186/s13287-024-03684-6. Stem Cell Res Ther. 2024. PMID: 38433223 Free PMC article.
OBJECTIVES: Currently, no approved stem cell-based therapies for preserving ovarian function during aging. To solve this problem, we developed a long-term treatment for human embryonic stem cell-derived mesenchymal progenitor cells (hESC-MPCs). ...MATERIALS AND METHODS: In …
OBJECTIVES: Currently, no approved stem cell-based therapies for preserving ovarian function during aging. To solve this problem, we develop …
Comparison of Radiologic Results after Lateral Meniscal Allograft Transplantation with or without Capsulodesis Using an All-Soft Suture Anchor.
Lee DR, Woo YJ, Moon SG, Kim WJ, Lee DW. Lee DR, et al. Medicina (Kaunas). 2022 Dec 20;59(1):1. doi: 10.3390/medicina59010001. Medicina (Kaunas). 2022. PMID: 36676625 Free PMC article.
Conclusions: In lateral MAT, capsulodesis (open decortication and suture anchor fixation) could reduce graft extrusion without complications. In the future, large-volume and long-term prospective comparative studies are needed to confirm the clinical effects following caps …
Conclusions: In lateral MAT, capsulodesis (open decortication and suture anchor fixation) could reduce graft extrusion without complications …
Generation of Skeletal Muscle Organoids from Human Pluripotent Stem Cells to Model Myogenesis and Muscle Regeneration.
Shin MK, Bang JS, Lee JE, Tran HD, Park G, Lee DR, Jo J. Shin MK, et al. Among authors: lee dr. Int J Mol Sci. 2022 May 4;23(9):5108. doi: 10.3390/ijms23095108. Int J Mol Sci. 2022. PMID: 35563499 Free PMC article.
Notably, we detected quiescent, non-dividing SCs throughout the hSkMO differentiation in long-term culture. They were activated and differentiated to reconstitute muscle tissue upon damage. ...
Notably, we detected quiescent, non-dividing SCs throughout the hSkMO differentiation in long-term culture. They were activated and d …
Hydrophobically Modified Cellulose Nanofibers-Enveloped Solid Lipid Microparticles for Improved Antioxidant Cargo Retention.
Bae J, Seo HM, Shin K, Choi J, Lee DR, Jiang Z, Shen D, Kim JW. Bae J, et al. Among authors: lee dr. Macromol Rapid Commun. 2022 Apr;43(7):e2100917. doi: 10.1002/marc.202100917. Epub 2022 Mar 7. Macromol Rapid Commun. 2022. PMID: 35213061
Because the diC(10) BCNF-enveloped SLMs exhibit a core molecular crystalline phase at the microscale, they can immobilize an oil-soluble antioxidant while maintaining its long-term storage stability. These findings show that the cellulose-surfactant-based SLM technology is …
Because the diC(10) BCNF-enveloped SLMs exhibit a core molecular crystalline phase at the microscale, they can immobilize an oil-soluble ant …
Identification and Characterization of Besifovir-Resistant Hepatitis B Virus Isolated from a Chronic Hepatitis B Patient.
Kim JC, Lee HY, Lee AR, Dezhbord M, Lee DR, Kim SH, Won J, Park S, Kim NY, Shin JJ, Kim SG, Kim YS, Yoo JJ, Kim KH. Kim JC, et al. Among authors: lee dr. Biomedicines. 2022 Jan 26;10(2):282. doi: 10.3390/biomedicines10020282. Biomedicines. 2022. PMID: 35203489 Free PMC article.
In this study, we found a CHB patient who showed viral breakthrough after long-term treatment with BSV. The isolated HBV DNA from patient's serum were cloned into the replication-competent HBV 1.2 mer and the sequence of reverse transcriptase (RT) domain of HBV polymerase …
In this study, we found a CHB patient who showed viral breakthrough after long-term treatment with BSV. The isolated HBV DNA from pat …
Effect of a Hybrid Closed-Loop System on Glycemic and Psychosocial Outcomes in Children and Adolescents With Type 1 Diabetes: A Randomized Clinical Trial.
Abraham MB, de Bock M, Smith GJ, Dart J, Fairchild JM, King BR, Ambler GR, Cameron FJ, McAuley SA, Keech AC, Jenkins A, Davis EA, O'Neal DN, Jones TW; Australian Juvenile Diabetes Research Fund Closed-Loop Research group. Abraham MB, et al. JAMA Pediatr. 2021 Dec 1;175(12):1227-1235. doi: 10.1001/jamapediatrics.2021.3965. JAMA Pediatr. 2021. PMID: 34633418 Free PMC article. Clinical Trial.
IMPORTANCE: Hybrid closed-loop (HCL) therapy has improved glycemic control in children and adolescents with type 1 diabetes; however, the efficacy of HCL on glycemic and psychosocial outcomes has not yet been established in a long-term randomized clinical trial. OBJECTIVE: …
IMPORTANCE: Hybrid closed-loop (HCL) therapy has improved glycemic control in children and adolescents with type 1 diabetes; however, the ef …
Distinct Repopulation Activity in Hu-Mice Between CB- and LPB-CD34＋ Cells by Enrichment of Transcription Factors.
Han AR, Lee JE, Lee MJ, Ko SY, Shin HS, Lee JY, Lee DR. Han AR, et al. Among authors: lee dr. Int J Stem Cells. 2021 May 30;14(2):203-211. doi: 10.15283/ijsc21015. Int J Stem Cells. 2021. PMID: 33906982 Free PMC article.
METHODS AND RESULTS: In this study, we established hu-mice that combined human characteristics with long-term survival and investigated the efficiency of the engraftment of lymphoid lineage cells derived from LPB- and CB-CD34(+) cells in the bone marrow, spleen, and LPB. . …
METHODS AND RESULTS: In this study, we established hu-mice that combined human characteristics with long-term survival and investigat …
Effect of simultaneous presence of anti-blood group A/B and -HLA antibodies on clinical outcomes in kidney transplantation across positive crossmatch: a nationwide cohort study.
Kwon H, Kim JY, Kim DH, Ko Y, Choi JY, Shin S, Jung JH, Kim YH, Han DJ; Korean Organ Transplantation Registry Study Group. Kwon H, et al. Sci Rep. 2019 Dec 3;9(1):18229. doi: 10.1038/s41598-019-54397-3. Sci Rep. 2019. PMID: 31796812 Free PMC article.
ABO incompatibility in XM-positive KT patients was found to be a significant risk factor for the development of rejection within one year after transplantation as well as for long-term graft survival. The anti-blood group A, B and anti-HLA antibodies may show synergistic a …
ABO incompatibility in XM-positive KT patients was found to be a significant risk factor for the development of rejection within one year af …
22 results