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[Cystic fibrosis - A look at Belgium in 2022].
Lebecque P, Bauraind O, Thimmesch M. Lebecque P, et al. Rev Med Liege. 2022 Sep;77(9):532-537. Rev Med Liege. 2022. PMID: 36082601 Free article. French.
The cost of this triple therapy is opaque and far too high. However, its effectiveness is impressive and, in the long term, around 90 % of Belgian patients with cystic fibrosis are expected to greatly benefit from it....
The cost of this triple therapy is opaque and far too high. However, its effectiveness is impressive and, in the long term, around 90 …
[Mucoviscidosis: CFTR mutation-specific therapy: a ray of sunshine in a cloudy sky].
Leonard A, Leal T, Lebecque P. Leonard A, et al. Among authors: lebecque p. Arch Pediatr. 2013 Jan;20(1):63-73. doi: 10.1016/j.arcped.2012.10.018. Epub 2012 Nov 27. Arch Pediatr. 2013. PMID: 23199563 Review. French.
Primarily targeting a mutation carried by less than 2% of French CF patients, the 2 Ivacaftor studies could well be a milestone on the long road toward a cure for CF. However, further data on safety and long-term efficacy are obviously needed and the current price of this …
Primarily targeting a mutation carried by less than 2% of French CF patients, the 2 Ivacaftor studies could well be a milestone on the long …
Molecular typing and antifungal susceptibility of Exophiala isolates from patients with cystic fibrosis.
Packeu A, Lebecque P, Rodriguez-Villalobos H, Boeras A, Hendrickx M, Bouchara JP, Symoens F. Packeu A, et al. Among authors: lebecque p. J Med Microbiol. 2012 Sep;61(Pt 9):1226-1233. doi: 10.1099/jmm.0.042317-0. Epub 2012 May 11. J Med Microbiol. 2012. PMID: 22580912 Free article.
Almost all the isolates were identified as E. dermatitidis, but long-term colonization with the closely related species E. phaeomuriformis was observed in one patient. ...
Almost all the isolates were identified as E. dermatitidis, but long-term colonization with the closely related species E. phaeomurif …
Gene signature of rat mammary glands: Influence of lifelong soy isoflavones consumption.
Chalabi N, Coxam V, Satih S, Davicco MJ, Lebecque P, Fontana L, Bignon YJ, Bernard-Gallon DJ. Chalabi N, et al. Among authors: lebecque p. Mol Med Rep. 2010 Jan-Feb;3(1):75-81. doi: 10.3892/mmr_00000221. Mol Med Rep. 2010. PMID: 21472203
This effect increased with animal age: in 3-, 18- and 24-month-old rats, 293, 441 and 2868 differentially expressed genes were respectively observed. These results suggest that long-term exposure to isoflavones may play a key role in gene regulation. ...
This effect increased with animal age: in 3-, 18- and 24-month-old rats, 293, 441 and 2868 differentially expressed genes were respectively …
Effects of isometric strength training followed by no exercise and Humulus lupulus L-enriched diet on bone metabolism in old female rats.
Figard H, Mougin F, Nappey M, Davicco MJ, Lebecque P, Coxam V, Lamothe V, Sauvant P, Berthelot A. Figard H, et al. Among authors: lebecque p. Metabolism. 2007 Dec;56(12):1673-81. doi: 10.1016/j.metabol.2007.07.010. Metabolism. 2007. PMID: 17998020
We investigated in female rats the effects on bone metabolism of a prolonged no-training period, subsequent to an isometric exercise program, performed during young adulthood and those of a long-term consumption of Humulus lupulus L-enriched diet (genistein 1.92 and daidze …
We investigated in female rats the effects on bone metabolism of a prolonged no-training period, subsequent to an isometric exercise program …
Modulation of soy isoflavones bioavailability and subsequent effects on bone health in ovariectomized rats: the case for equol.
Mathey J, Mardon J, Fokialakis N, Puel C, Kati-Coulibaly S, Mitakou S, Bennetau-Pelissero C, Lamothe V, Davicco MJ, Lebecque P, Horcajada MN, Coxam V. Mathey J, et al. Among authors: lebecque p. Osteoporos Int. 2007 May;18(5):671-9. doi: 10.1007/s00198-007-0351-y. Epub 2007 Feb 28. Osteoporos Int. 2007. PMID: 17333448
The effects of lactobacillus were similar, except that the increase in metaphyseal-BMD was not significant. CONCLUSION: In conclusion, long-term equol consumption, like genistein and daidzein, in the ovariectomized rat, provides bone sparing effects. ...
The effects of lactobacillus were similar, except that the increase in metaphyseal-BMD was not significant. CONCLUSION: In conclusion, long- …