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Association between Airport Ultrafine Particles and Lung Cancer Risk: The Multiethnic Cohort Study.
Bookstein A, Po J, Tseng C, Larson TV, Yang J, Park SL, Wu J, Shariff-Marco S, Inamdar PP, Ihenacho U, Setiawan VW, DeRouen MC, Le Marchand L, Stram DO, Samet J, Ritz B, Fruin S, Wu AH, Cheng I. Bookstein A, et al. Among authors: le marchand l. Cancer Epidemiol Biomarkers Prev. 2024 Feb 19. doi: 10.1158/1055-9965.EPI-23-0924. Online ahead of print. Cancer Epidemiol Biomarkers Prev. 2024. PMID: 38372643
Emerging evidence suggests that UFPs may impact lung health due to their high surface area-to-mass ratio and deep penetration into airways. This study aimed to assess long-term exposure to airport-related UFPs and lung cancer incidence in a multiethnic population in Los An …
Emerging evidence suggests that UFPs may impact lung health due to their high surface area-to-mass ratio and deep penetration into airways. …
Long-term association between diet quality and characteristics of the gut microbiome in the multiethnic cohort study.
Ma E, Maskarinec G, Lim U, Boushey CJ, Wilkens LR, Setiawan VW, Le Marchand L, Randolph TW, Jenkins IC, Curtis KR, Lampe JW, Hullar MAJ. Ma E, et al. Among authors: le marchand l. Br J Nutr. 2021 Aug 9:1-10. doi: 10.1017/S0007114521002968. Online ahead of print. Br J Nutr. 2021. PMID: 34369335 Free PMC article.
The quality of past diet, assessed as far as 20 years before stool collection, is equally predictive of GM composition as concurrently assessed diet, indicative of the long-term consistency of this relation....
The quality of past diet, assessed as far as 20 years before stool collection, is equally predictive of GM composition as concurrently asses …
Breast Cancer Risk Factors and Survival by Tumor Subtype: Pooled Analyses from the Breast Cancer Association Consortium.
Morra A, Jung AY, Behrens S, Keeman R, Ahearn TU, Anton-Culver H, Arndt V, Augustinsson A, Auvinen PK, Beane Freeman LE, Becher H, Beckmann MW, Blomqvist C, Bojesen SE, Bolla MK, Brenner H, Briceno I, Brucker SY, Camp NJ, Campa D, Canzian F, Castelao JE, Chanock SJ, Choi JY, Clarke CL, Couch FJ, Cox A, Cross SS, Czene K, Dörk T, Dunning AM, Dwek M, Easton DF, Eccles DM, Egan KM, Evans DG, Fasching PA, Flyger H, Gago-Dominguez M, Gapstur SM, García-Sáenz JA, Gaudet MM, Giles GG, Grip M, Guénel P, Haiman CA, Håkansson N, Hall P, Hamann U, Han SN, Hart SN, Hartman M, Heyworth JS, Hoppe R, Hopper JL, Hunter DJ, Ito H, Jager A, Jakimovska M, Jakubowska A, Janni W, Kaaks R, Kang D, Kapoor PM, Kitahara CM, Koutros S, Kraft P, Kristensen VN, Lacey JV, Lambrechts D, Le Marchand L, Li J, Lindblom A, Lubiński J, Lush M, Mannermaa A, Manoochehri M, Margolin S, Mariapun S, Matsuo K, Mavroudis D, Milne RL, Muranen TA, Newman WG, Noh DY, Nordestgaard BG, Obi N, Olshan AF, Olsson H, Park-Simon TW, Petridis C, Pharoah PDP, Plaseska-Karanfilska D, Presneau N, Rashid MU, Rennert G, Rennert HS, Rhenius V, Romero A, Saloustros E, Sawyer EJ, Schneeweiss A, Schwentner L, Scott C, Shah M, Shen CY,… See abstract for full author list ➔ Morra A, et al. Among authors: le marchand l. Cancer Epidemiol Biomarkers Prev. 2021 Apr;30(4):623-642. doi: 10.1158/1055-9965.EPI-20-0924. Epub 2021 Jan 26. Cancer Epidemiol Biomarkers Prev. 2021. PMID: 33500318 Free PMC article.
The strongest associations were between all-cause mortality and BMI 30 versus 18.5-25 kg/m(2) [HR (95% confidence interval (CI), 1.19 (1.06-1.34)]; current versus never smoking [1.37 (1.27-1.47)], high versus low physical activity [0.43 (0.21-0.86)], age 30 years versus <20 ye …
The strongest associations were between all-cause mortality and BMI 30 versus 18.5-25 kg/m(2) [HR (95% confidence interval (CI), 1.19 (1.06- …
Changes in diet quality and body weight over 10 years: the Multiethnic Cohort Study.
Kang M, Boushey CJ, Shvetsov YB, Setiawan VW, Paik HY, Wilkens LR, Le Marchand L, Park SY. Kang M, et al. Among authors: le marchand l. Br J Nutr. 2021 Nov 14;126(9):1389-1397. doi: 10.1017/S000711452100012X. Epub 2021 Jan 14. Br J Nutr. 2021. PMID: 33441193 Free PMC article.
High-quality diets have been found to be beneficial in preventing long-term weight gain. However, concurrent changes in diet quality and body weight over time have rarely been reported. ...
High-quality diets have been found to be beneficial in preventing long-term weight gain. However, concurrent changes in diet quality …
Auto-antibodies to p53 and the Subsequent Development of Colorectal Cancer in a U.S. Prospective Cohort Consortium.
Butt J, Blot WJ, Visvanathan K, Le Marchand L, Wilkens LR, Chen Y, Sesso HD, Teras L, Ryser MD, Hyslop T, Wassertheil-Smoller S, Tinker LF, Potter JD, Song M, Berndt SI, Waterboer T, Pawlita M, Epplein M. Butt J, et al. Among authors: le marchand l. Cancer Epidemiol Biomarkers Prev. 2020 Dec;29(12):2729-2734. doi: 10.1158/1055-9965.EPI-20-0780. Epub 2020 Sep 24. Cancer Epidemiol Biomarkers Prev. 2020. PMID: 32972968 Free PMC article.
IMPACT: Our finding suggests that p53 seropositivity may not be a useful predictor of long-term colorectal cancer risk; however, it might be considered as a marker to aid in the early diagnosis of colorectal cancer....
IMPACT: Our finding suggests that p53 seropositivity may not be a useful predictor of long-term colorectal cancer risk; however, it m …
Racial/Ethnic Differences in Lung Cancer Incidence in the Multiethnic Cohort Study: An Update.
Stram DO, Park SL, Haiman CA, Murphy SE, Patel Y, Hecht SS, Le Marchand L. Stram DO, et al. Among authors: le marchand l. J Natl Cancer Inst. 2019 Aug 1;111(8):811-819. doi: 10.1093/jnci/djy206. J Natl Cancer Inst. 2019. PMID: 30698722 Free PMC article.
METHODS: We apportioned lung cancer risk into three parts: age-specific background risk (among never smokers), an excess relative risk term for cumulative smoking, and modifiers of the smoking effect: race and years-quit smoking. ...
METHODS: We apportioned lung cancer risk into three parts: age-specific background risk (among never smokers), an excess relative risk te
Diet quality measured by four a priori-defined diet quality indices is associated with lipid-soluble micronutrients in the Multiethnic Cohort Study (MEC).
Aumueller N, Boushey CJ, Franke AA, Cooney RV, Monroe KR, Haiman CA, Wilkens LR, Kolonel LN, Le Marchand L, Maskarinec G. Aumueller N, et al. Among authors: le marchand l. Eur J Clin Nutr. 2019 May;73(5):703-713. doi: 10.1038/s41430-018-0272-1. Epub 2018 Aug 2. Eur J Clin Nutr. 2019. PMID: 30072814 Free PMC article.
BACKGROUND/OBJECTIVES: This study examined the long-term relation of lipid-soluble micronutrients with diet quality as assessed by four a priori-defined dietary patterns. ...
BACKGROUND/OBJECTIVES: This study examined the long-term relation of lipid-soluble micronutrients with diet quality as assessed by fo …
Antibody Responses to Streptococcus Gallolyticus Subspecies Gallolyticus Proteins in a Large Prospective Colorectal Cancer Cohort Consortium.
Butt J, Blot WJ, Teras LR, Visvanathan K, Le Marchand L, Haiman CA, Chen Y, Bao Y, Sesso HD, Wassertheil-Smoller S, Ho GY, Tinker LF, Peek RM, Potter JD, Cover TL, Hendrix LH, Huang LC, Waterboer T, Pawlita M, Epplein M. Butt J, et al. Among authors: le marchand l. Cancer Epidemiol Biomarkers Prev. 2018 Oct;27(10):1186-1194. doi: 10.1158/1055-9965.EPI-18-0249. Epub 2018 Jul 23. Cancer Epidemiol Biomarkers Prev. 2018. PMID: 30038049 Free PMC article.
Previous case-control studies and prospective studies with up to 8 years of follow-up, however, were unable to decipher the temporality of antibody responses to SGG in the context of the long-term multistep development of colorectal cancer. In this study, we analyzed a lar …
Previous case-control studies and prospective studies with up to 8 years of follow-up, however, were unable to decipher the temporality of a …
Genetic modifiers of radon-induced lung cancer risk: a genome-wide interaction study in former uranium miners.
Rosenberger A, Hung RJ, Christiani DC, Caporaso NE, Liu G, Bojesen SE, Le Marchand L, Haiman CA, Albanes D, Aldrich MC, Tardon A, Fernández-Tardón G, Rennert G, Field JK, Kiemeney B, Lazarus P, Haugen A, Zienolddiny S, Lam S, Schabath MB, Andrew AS, Brunnsstöm H, Goodman GE, Doherty JA, Chen C, Teare MD, Wichmann HE, Manz J, Risch A, Muley TR, Johansson M, Brennan P, Landi MT, Amos CI, Pesch B, Johnen G, Brüning T, Bickeböller H, Gomolka M. Rosenberger A, et al. Among authors: le marchand l. Int Arch Occup Environ Health. 2018 Nov;91(8):937-950. doi: 10.1007/s00420-018-1334-3. Epub 2018 Jul 3. Int Arch Occup Environ Health. 2018. PMID: 29971594 Free PMC article.
At least suggestive significant interaction of linkage disequilibrium blocks was observed at the chromosomal regions 18q21.23 (p = 1.2 10(-6)), 5q23.2 (p = 2.5 10(-6)), 1q21.3 (p = 3.2 10(-6)), 10p13 (p = 1.3 10(-5)) and 12p12.1 (p = 7.1 10(-5)). Genes belonging to the Gene Ontol …
At least suggestive significant interaction of linkage disequilibrium blocks was observed at the chromosomal regions 18q21.23 (p = 1.2 10(-6 …
Pancreatic Cancer Following Incident Diabetes in African Americans and Latinos: The Multiethnic Cohort.
Setiawan VW, Stram DO, Porcel J, Chari ST, Maskarinec G, Le Marchand L, Wilkens LR, Haiman CA, Pandol SJ, Monroe KR. Setiawan VW, et al. Among authors: le marchand l. J Natl Cancer Inst. 2019 Jan 1;111(1):27-33. doi: 10.1093/jnci/djy090. J Natl Cancer Inst. 2019. PMID: 29917105 Free PMC article.
Individuals with recent-onset diabetes (within three or fewer years of PC diagnosis) had a greater risk compared with those with long-term diabetes across all ages. The HRage75 for recent-onset diabetes was 4.08 (95% CI = 2.76 to 6.03) in Latinos and 3.38 (95% CI = 2.30 to …
Individuals with recent-onset diabetes (within three or fewer years of PC diagnosis) had a greater risk compared with those with long-ter
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