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Evolution of hepatitis C virus quasispecies during repeated treatment with the NS3/4A protease inhibitor telaprevir.
Susser S, Flinders M, Reesink HW, Zeuzem S, Lawyer G, Ghys A, Van Eygen V, Witek J, De Meyer S, Sarrazin C. Susser S, et al. Antimicrob Agents Chemother. 2015 May;59(5):2746-55. doi: 10.1128/AAC.04911-14. Epub 2015 Feb 23. Antimicrob Agents Chemother. 2015. PMID: 25712364 Free PMC article. Clinical Trial.
Antiviral therapy for chronic viral infections, like HIV, hepatitis B virus (HBV), or hepatitis C virus (HCV), faces several challenges. These viruses have evolved survival strategies and proliferate by escaping the host's immune system. ...Interestingly, in contrast to HI …
Antiviral therapy for chronic viral infections, like HIV, hepatitis B virus (HBV), or hepatitis C virus (HCV), faces several challeng …
Vulnerable Immigrant Populations in the New York Metropolitan Area and COVID-19: Lessons Learned in the Epicenter of the Crisis.
Behbahani S, Smith CA, Carvalho M, Warren CJ, Gregory M, Silva NA. Behbahani S, et al. Acad Med. 2020 Dec;95(12):1827-1830. doi: 10.1097/ACM.0000000000003518. Acad Med. 2020. PMID: 32452838 Free PMC article.
It has been challenging for this population to access public information regarding COVID-19 testing, treatment, and assistance programs because this information has seldom been disseminated in Spanish and even less frequently in Portuguese. While long-term solutions will r …
It has been challenging for this population to access public information regarding COVID-19 testing, treatment, and assistance programs beca …
Quantification of the infectious dose of Leishmania major transmitted to the skin by single sand flies.
Kimblin N, Peters N, Debrabant A, Secundino N, Egen J, Lawyer P, Fay MP, Kamhawi S, Sacks D. Kimblin N, et al. Proc Natl Acad Sci U S A. 2008 Jul 22;105(29):10125-30. doi: 10.1073/pnas.0802331105. Epub 2008 Jul 14. Proc Natl Acad Sci U S A. 2008. PMID: 18626016 Free PMC article.
The low dose resulted in only minor pathology but a higher parasite titer in the chronic phase, and it established the host as an efficient long-term reservoir of infection back to vector sand flies....
The low dose resulted in only minor pathology but a higher parasite titer in the chronic phase, and it established the host as an efficient …