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Eosinophilic granulomatosis with polyangiitis (Churg-Strauss): clinical characteristics and long-term followup of the 383 patients enrolled in the French Vasculitis Study Group cohort.
Comarmond C, Pagnoux C, Khellaf M, Cordier JF, Hamidou M, Viallard JF, Maurier F, Jouneau S, Bienvenu B, Puéchal X, Aumaître O, Le Guenno G, Le Quellec A, Cevallos R, Fain O, Godeau B, Seror R, Dunogué B, Mahr A, Guilpain P, Cohen P, Aouba A, Mouthon L, Guillevin L; French Vasculitis Study Group. Comarmond C, et al. Arthritis Rheum. 2013 Jan;65(1):270-81. doi: 10.1002/art.37721. Arthritis Rheum. 2013. PMID: 23044708 Free article.
This study was undertaken to describe the main characteristics of a larger patient cohort and their long-term outcomes. METHODS: A retrospective study of EGPA patients in the French Vasculitis Study Group cohort who satisfied the American College of Rheumatology criteria a …
This study was undertaken to describe the main characteristics of a larger patient cohort and their long-term outcomes. METHODS: A re …
Long-term outcomes of 118 patients with eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome) enrolled in two prospective trials.
Samson M, Puéchal X, Devilliers H, Ribi C, Cohen P, Stern M, Pagnoux C, Mouthon L, Guillevin L; French Vasculitis Study Group. Samson M, et al. J Autoimmun. 2013 Jun;43:60-9. doi: 10.1016/j.jaut.2013.03.003. Epub 2013 Apr 13. J Autoimmun. 2013. PMID: 23590801 Clinical Trial.
Mean SD follow-up was 81.3 39.6 months. Among the 118 patients studied, 29% achieved long-term remission and 10% died. Among the 115 patients achieving a first remission, 41% experienced 1 relapses, 26.1 26.8 months after treatment onset, with 57% of relapses occurring whe …
Mean SD follow-up was 81.3 39.6 months. Among the 118 patients studied, 29% achieved long-term remission and 10% died. Among the 115 …
Idiopathic chronic eosinophilic pneumonia and asthma: how do they influence each other?
Marchand E, Etienne-Mastroianni B, Chanez P, Lauque D, Leclerc P, Cordier JF; Groupe d'Etudes et de Recherche sur les Maladies Orphelines Pulmonaires. Marchand E, et al. Among authors: lauque d. Eur Respir J. 2003 Jul;22(1):8-13. doi: 10.1183/09031936.03.00085603. Eur Respir J. 2003. PMID: 12882444 Free article.
Patients with asthma at the time of diagnosis of ICEP were more likely to remain free of relapse of ICEP (56 versus 23%) and had a lower number of relapses per year of follow-up (median 0 versus 0.24). Moreover, they were treated more frequently with long-term inhaled cort …
Patients with asthma at the time of diagnosis of ICEP were more likely to remain free of relapse of ICEP (56 versus 23%) and had a lower num …
Clinical manifestations of anti-synthetase syndrome positive for anti-alanyl-tRNA synthetase (anti-PL12) antibodies: a retrospective study of 17 cases.
Hervier B, Wallaert B, Hachulla E, Adoue D, Lauque D, Audrain M, Camara B, Fournie B, Couret B, Hatron PY, Dubucquoi S, Hamidou M. Hervier B, et al. Among authors: lauque d. Rheumatology (Oxford). 2010 May;49(5):972-6. doi: 10.1093/rheumatology/kep455. Epub 2010 Feb 15. Rheumatology (Oxford). 2010. PMID: 20156976
Four patients suffered from SS, and four others had an atypical oesophageal involvement. The long-term course was assessable for 10 patients (follow-up of 41.1 months). ...
Four patients suffered from SS, and four others had an atypical oesophageal involvement. The long-term course was assessable for 10 p …
Microscopic polyangiitis with alveolar hemorrhage. A study of 29 cases and review of the literature. Groupe d'Etudes et de Recherche sur les Maladies "Orphelines" Pulmonaires (GERM"O"P).
Lauque D, Cadranel J, Lazor R, Pourrat J, Ronco P, Guillevin L, Cordier JF. Lauque D, et al. Medicine (Baltimore). 2000 Jul;79(4):222-33. doi: 10.1097/00005792-200007000-00003. Medicine (Baltimore). 2000. PMID: 10941351 Free article.
In this retrospective study of 29 patients with MPA and alveolar hemorrhage (AH), we characterized the pulmonary manifestations at presentation and assessed the short- and long-term outcome. AH was diagnosed when bronchoalveolar lavage was macroscopically bloody, or contai …
In this retrospective study of 29 patients with MPA and alveolar hemorrhage (AH), we characterized the pulmonary manifestations at presentat …
Treatment of Churg-Strauss syndrome without poor-prognosis factors: a multicenter, prospective, randomized, open-label study of seventy-two patients.
Ribi C, Cohen P, Pagnoux C, Mahr A, Arène JP, Lauque D, Puéchal X, Letellier P, Delaval P, Cordier JF, Guillevin L; French Vasculitis Study Group. Ribi C, et al. Among authors: lauque d. Arthritis Rheum. 2008 Feb;58(2):586-94. doi: 10.1002/art.23198. Arthritis Rheum. 2008. PMID: 18240234 Free article. Clinical Trial.
AZA or pulse CYC was fairly effective in treating CS-resistant disease or major relapses. Over the long term, most patients continued to take oral CS, which might explain the high rate of CS-related adverse events....
AZA or pulse CYC was fairly effective in treating CS-resistant disease or major relapses. Over the long term, most patients continued …
Idiopathic chronic eosinophilic pneumonia. A clinical and follow-up study of 62 cases. The Groupe d'Etudes et de Recherche sur les Maladies "Orphelines" Pulmonaires (GERM"O"P).
Marchand E, Reynaud-Gaubert M, Lauque D, Durieu J, Tonnel AB, Cordier JF. Marchand E, et al. Among authors: lauque d. Medicine (Baltimore). 1998 Sep;77(5):299-312. doi: 10.1097/00005792-199809000-00001. Medicine (Baltimore). 1998. PMID: 9772920 Free article.
The disorder is highly responsive to oral corticosteroid therapy, but relapses are frequent on reducing or stopping treatment. The long-term course of the disease and data regarding outcome, particularly the need for prolonged oral corticosteroid therapy and the developmen …
The disorder is highly responsive to oral corticosteroid therapy, but relapses are frequent on reducing or stopping treatment. The long-t …
Prescription medicines and the risk of road traffic crashes: a French registry-based study.
Orriols L, Delorme B, Gadegbeku B, Tricotel A, Contrand B, Laumon B, Salmi LR, Lagarde E; CESIR research group. Orriols L, et al. PLoS Med. 2010 Nov 16;7(11):e1000366. doi: 10.1371/journal.pmed.1000366. PLoS Med. 2010. PMID: 21125020 Free PMC article.
The association remained after adjustment for the presence of a long-term chronic disease. The fraction of road traffic crashes attributable to levels 2 and 3 medications was 3.3% [2.7%-3.9%]. ...
The association remained after adjustment for the presence of a long-term chronic disease. The fraction of road traffic crashes attri …
A prospective, multicenter, randomized trial comparing steroids and pulse cyclophosphamide versus steroids and oral cyclophosphamide in the treatment of generalized Wegener's granulomatosis.
Guillevin L, Cordier JF, Lhote F, Cohen P, Jarrousse B, Royer I, Lesavre P, Jacquot C, Bindi P, Bielefeld P, Desson JF, Détrée F, Dubois A, Hachulla E, Hoen B, Jacomy D, Seigneuric C, Lauque D, Stern M, Longy-Boursier M. Guillevin L, et al. Among authors: lauque d. Arthritis Rheum. 1997 Dec;40(12):2187-98. doi: 10.1002/art.1780401213. Arthritis Rheum. 1997. PMID: 9416856 Clinical Trial.
CONCLUSION: Our results indicate that pulse CYC is as effective as oral CYC in achieving initial remission of WG and is associated with fewer side effects and lower mortality. However, in the long term, treatment with pulse CYC does not maintain remission or prevent relaps …
CONCLUSION: Our results indicate that pulse CYC is as effective as oral CYC in achieving initial remission of WG and is associated with fewe …