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Effects of statin therapy on diagnoses of new-onset diabetes and worsening glycaemia in large-scale randomised blinded statin trials: an individual participant data meta-analysis.
Cholesterol Treatment Trialists’ (CTT) Collaboration. Electronic address: ctt@ndph.ox.ac.uk; Cholesterol Treatment Trialists’ (CTT) Collaboration. Cholesterol Treatment Trialists’ (CTT) Collaboration. Electronic address: ctt@ndph.ox.ac.uk, et al. Lancet Diabetes Endocrinol. 2024 May;12(5):306-319. doi: 10.1016/S2213-8587(24)00040-8. Epub 2024 Mar 27. Lancet Diabetes Endocrinol. 2024. PMID: 38554713 Free article.
We aimed to address these gaps in knowledge through analysis of individual participant data from large, long-term, randomised, double-blind trials of statin therapy. METHODS: We conducted a meta-analysis of individual participant data from randomised controlled trials of s …
We aimed to address these gaps in knowledge through analysis of individual participant data from large, long-term, randomised, double …
Long-term cardiovascular risks and the impact of statin treatment on socioeconomic inequalities: a microsimulation model.
Wu R, Williams C, Zhou J, Schlackow I, Emberson J, Reith C, Keech A, Robson J, Armitage J, Gray A, Simes J, Baigent C, Mihaylova B; CTT Collaboration secretariat; Armitage J, Baigent C, Barnes E, Blackwell L, Collins R, Davies K, Emberson J, Fulcher J, Halls H, Herrington WG, Holland L, Keech A, Kirby A, Mihaylova B, O'Connell R, Preiss D, Reith C, Simes J, Wilson K; CTT Collaboration trialists: A to Z trial (phase Z); Blazing M, Braunwald E, Lemos J, Murphy S, Pedersen TR, Pfeffer M, White H, Wiviott S; AFCAPS/TEXCAPS (AirForce/Texas Coronary Atherosclerosis Prevention Study); Clearfield M, Downs JR, Gotto A Jr, Weis S; ALERT (Assessment of Lescol in Renal Transplantation); Fellström B, Holdaas H, Jardine A, Pedersen TR; ALLHAT (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial); Gordon D, Davis B, Furberg C, Grimm R, Pressel S, Probstfield JL, Rahman M, Simpson L; ALLIANCE (Aggressive Lipid-Lowering Initiation Abates New Cardiac Events); Koren M; ASCOT (Anglo-Scandinavian Cardiac Outcomes Trial); Dahlöf B, Gupta A, Poulter N, Sever P, Wedel H; ASPEN (Atorvastatin Study for the Prevention of Coronary Heart Disease Endpoints in Non-Insulin Dependent Diabe… See abstract for full author list ➔ Wu R, et al. Among authors: latini r. Br J Gen Pract. 2024 Feb 19;74(740):e189-98. doi: 10.3399/BJGP.2023.0198. Online ahead of print. Br J Gen Pract. 2024. PMID: 38373851 Free PMC article.
CONCLUSION: The study demonstrated the potential of guideline-recommended statin treatment to reduce socioeconomic inequalities. This CVD model is a novel resource for individualised long-term projections of health outcomes of CVD treatments....
CONCLUSION: The study demonstrated the potential of guideline-recommended statin treatment to reduce socioeconomic inequalities. This CVD mo …
High amplitude spectrum area measured in real-time during cardiopulmonary resuscitation is associated with favourable long-term neurological outcome after out-of-hospital cardiac arrest.
Meessen JMTA, Ruggeri L, Fumagalli F, Semeraro F, Bernasconi F, Magliocca A, Cerrato M, Merigo G, De Giorgio D, Migliari M, Latini R, Ristagno G. Meessen JMTA, et al. Among authors: latini r. J Clin Anesth. 2024 May;93:111323. doi: 10.1016/j.jclinane.2023.111323. Epub 2023 Dec 2. J Clin Anesth. 2024. PMID: 38043375 No abstract available.
Characterization of the Cardiac Structure and Function of Conscious D2.B10-Dmdmdx/J (D2-mdx) mice from 16-17 to 24-25 Weeks of Age.
De Giorgio D, Novelli D, Motta F, Cerrato M, Olivari D, Salama A, Fumagalli F, Latini R, Staszewsky L, Crippa L, Steinkühler C, Licandro SA. De Giorgio D, et al. Among authors: latini r. Int J Mol Sci. 2023 Jul 22;24(14):11805. doi: 10.3390/ijms241411805. Int J Mol Sci. 2023. PMID: 37511564 Free PMC article.
We confirmed that right ventricle epicardial fibrosis is the most outstanding finding in D2-mdx mice. Further long-term studies are needed to evaluate whether this mouse model can also be considered a model of DMD cardiomyopathy....
We confirmed that right ventricle epicardial fibrosis is the most outstanding finding in D2-mdx mice. Further long-term studies are n …
Sirolimus-Coated Balloon in an All-Comer Population of Coronary Artery Disease Patients: The EASTBOURNE Prospective Registry.
Cortese B, Testa L, Heang TM, Ielasi A, Bossi I, Latini RA, Lee CY, Perez IS, Milazzo D, Caiazzo G, Tomai F, Benincasa S, Nuruddin AA, Stefanini G, Buccheri D, Seresini G, Singh R, Karavolias G, Cacucci M, Sciahbasi A, Ocaranza R, Menown IBA, Torres A, Sengottvelu G, Zanetti A, Pesenti N, Colombo A; EASTBOURNE Investigators. Cortese B, et al. Among authors: latini ra. JACC Cardiovasc Interv. 2023 Jul 24;16(14):1794-1803. doi: 10.1016/j.jcin.2023.05.005. JACC Cardiovasc Interv. 2023. PMID: 37495352
CONCLUSIONS: EASTBOURNE, the largest DCB study in the coronary field, shows the safety and efficacy of a novel SCB in a broad population of coronary artery disease including small vessels and ISR patients at mid-term follow-up. (The All-Comers Sirolimus-Coated Balloon Euro …
CONCLUSIONS: EASTBOURNE, the largest DCB study in the coronary field, shows the safety and efficacy of a novel SCB in a broad population of …
Markers of neutrophil mediated inflammation associate with disturbed continuous electroencephalogram after out of hospital cardiac arrest.
Pekkarinen PT, Carbone F, Minetti S, Ramoni D, Ristagno G, Latini R, Wihersaari L, Blennow K, Zetterberg H, Toppila J, Jakkula P, Reinikainen M, Montecucco F, Skrifvars MB. Pekkarinen PT, et al. Among authors: latini r. Acta Anaesthesiol Scand. 2023 Jan;67(1):94-103. doi: 10.1111/aas.14145. Epub 2022 Sep 12. Acta Anaesthesiol Scand. 2023. PMID: 36053856 Free PMC article.
We defined 6-month cerebral performance category (CPC) 1-2 as good and CPC 3-5 as poor long-term neurological outcome. We compared the prognostic value of biomarkers for 6-month neurological outcome to neurofilament light (NFL) measured at 48 h. ...However, the studied inf …
We defined 6-month cerebral performance category (CPC) 1-2 as good and CPC 3-5 as poor long-term neurological outcome. We compared th …
Effect of statin therapy on muscle symptoms: an individual participant data meta-analysis of large-scale, randomised, double-blind trials.
Cholesterol Treatment Trialists' Collaboration. Cholesterol Treatment Trialists' Collaboration. Lancet. 2022 Sep 10;400(10355):832-845. doi: 10.1016/S0140-6736(22)01545-8. Epub 2022 Aug 29. Lancet. 2022. PMID: 36049498 Free PMC article.
We aimed to address these through an individual participant data meta-analysis of all recorded adverse muscle events in large, long-term, randomised, double-blind trials of statin therapy. METHODS: Randomised trials of statin therapy were eligible if they aimed to recruit …
We aimed to address these through an individual participant data meta-analysis of all recorded adverse muscle events in large, long-term …
Red blood cell fatty acid patterns from 7 countries: Focus on the Omega-3 index.
Schuchardt JP, Cerrato M, Ceseri M, DeFina LF, Delgado GE, Gellert S, Hahn A, Howard BV, Kadota A, Kleber ME, Latini R, Maerz W, Manson JE, Mora S, Park Y, Sala-Vila A, von Schacky C, Sekikawa A, Tintle N, Tucker KL, Vasan RS, Harris WS. Schuchardt JP, et al. Among authors: latini r. Prostaglandins Leukot Essent Fatty Acids. 2022 Apr;179:102418. doi: 10.1016/j.plefa.2022.102418. Epub 2022 Mar 24. Prostaglandins Leukot Essent Fatty Acids. 2022. PMID: 35366625 Free PMC article.
Red blood cell (RBC) fatty acid (FA) patterns are becoming recognized as long-term biomarkers of tissue FA composition, but different analytical methods have complicated inter-study and international comparisons. ...
Red blood cell (RBC) fatty acid (FA) patterns are becoming recognized as long-term biomarkers of tissue FA composition, but different …
Neurofilament light compared to neuron-specific enolase as a predictor of unfavourable outcome after out-of-hospital cardiac arrest.
Wihersaari L, Reinikainen M, Furlan R, Mandelli A, Vaahersalo J, Kurola J, Tiainen M, Pettilä V, Bendel S, Varpula T, Latini R, Ristagno G, Skrifvars MB. Wihersaari L, et al. Among authors: latini r. Resuscitation. 2022 May;174:1-8. doi: 10.1016/j.resuscitation.2022.02.024. Epub 2022 Mar 1. Resuscitation. 2022. PMID: 35245610 Free article.
CONCLUSION: Compared to NSE, NfL demonstrated superior accuracy in predicting long-term unfavourable outcome after OHCA....
CONCLUSION: Compared to NSE, NfL demonstrated superior accuracy in predicting long-term unfavourable outcome after OHCA....
Optical coherence tomography, intravascular ultrasound or angiography guidance for distal left main coronary stenting. The ROCK cohort II study.
Cortese B, de la Torre Hernandez JM, Lanocha M, Ielasi A, Giannini F, Campo G, D'Ascenzo F, Latini RA, Krestianinov O, Alfonso F, Trani C, Prati F, Linares JA, Sardella G, Wlodarczak A, Viganò E, Camarero TG, Stella P, Sozykin A, Fineschi M, Burzotta F. Cortese B, et al. Among authors: latini ra. Catheter Cardiovasc Interv. 2022 Feb;99(3):664-673. doi: 10.1002/ccd.29959. Epub 2021 Sep 28. Catheter Cardiovasc Interv. 2022. PMID: 34582631
OBJECTIVES: to test the safety and efficacy of intravascular imaging and specifically optical coherence tomography (OCT) as a diagnostic tool for left main angioplasty and analyze the mid-term outcome accordingly. BACKGROUND: Clinical data and international guidelines reco …
OBJECTIVES: to test the safety and efficacy of intravascular imaging and specifically optical coherence tomography (OCT) as a diagnostic too …
64 results