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1991 1
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2024 0

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Diesel exhaust particulate (DEP) and nanoparticle exposures: what do DEP human clinical studies tell us about potential human health hazards of nanoparticles?
Hesterberg TW, Long CM, Lapin CA, Hamade AK, Valberg PA. Hesterberg TW, et al. Among authors: lapin ca. Inhal Toxicol. 2010 Jul;22(8):679-94. doi: 10.3109/08958371003758823. Inhal Toxicol. 2010. PMID: 20462394 Review.
Recent human DE exposure studies, using sensitive physiological instrumentation and well-characterized exposure concentrations and durations, suggest that elevated DE exposures from pre-2007 engines may trigger short-term changes in, for example, lung and systemic inflamma …
Recent human DE exposure studies, using sensitive physiological instrumentation and well-characterized exposure concentrations and durations …
Long-term inhaled dry powder mannitol in cystic fibrosis: an international randomized study.
Aitken ML, Bellon G, De Boeck K, Flume PA, Fox HG, Geller DE, Haarman EG, Hebestreit HU, Lapey A, Schou IM, Zuckerman JB, Charlton B; CF302 Investigators. Aitken ML, et al. Am J Respir Crit Care Med. 2012 Mar 15;185(6):645-52. doi: 10.1164/rccm.201109-1666OC. Epub 2011 Dec 28. Am J Respir Crit Care Med. 2012. PMID: 22198974 Clinical Trial.
RATIONALE: New treatment strategies are needed to improve airway clearance and reduce the morbidity and the time burden associated with cystic fibrosis (CF). OBJECTIVES: To determine whether long-term treatment with inhaled mannitol, an osmotic agent, improves lung functio …
RATIONALE: New treatment strategies are needed to improve airway clearance and reduce the morbidity and the time burden associated with cyst …
A subchronic inhalation toxicity study in rats exposed to silicon carbide whiskers.
Lapin CA, Craig DK, Valerio MG, McCandless JB, Bogoroch R. Lapin CA, et al. Fundam Appl Toxicol. 1991 Jan;16(1):128-46. doi: 10.1016/0272-0590(91)90142-q. Fundam Appl Toxicol. 1991. PMID: 2019338
Incidence and severity appeared to be dose-related. Therefore, until longer term studies are undertaken and it is established whether the above observed lesions will progress to more severe pathological entities, it is prudent to adopt stringent handling procedures for sil …
Incidence and severity appeared to be dose-related. Therefore, until longer term studies are undertaken and it is established whether …
Improved pulmonary and growth outcomes in cystic fibrosis by newborn screening.
Collins MS, Abbott MA, Wakefield DB, Lapin CD, Drapeau G, Hopfer SM, Greenstein RM, Cloutier MM. Collins MS, et al. Among authors: lapin cd. Pediatr Pulmonol. 2008 Jul;43(7):648-55. doi: 10.1002/ppul.20842. Pediatr Pulmonol. 2008. PMID: 18500732
BACKGROUND: Newborn screening for cystic fibrosis (CF) is effective in improving long-term growth outcomes. However, there is conflicting evidence that early diagnosis maintains normal pulmonary function. ...
BACKGROUND: Newborn screening for cystic fibrosis (CF) is effective in improving long-term growth outcomes. However, there is conflic …