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Cryo-electron microscopy structure of the lysosomal calcium-permeable channel TRPML3.
Hirschi M, Herzik MA Jr, Wie J, Suo Y, Borschel WF, Ren D, Lander GC, Lee SY. Hirschi M, et al. Among authors: lander gc. Nature. 2017 Oct 19;550(7676):411-414. doi: 10.1038/nature24055. Epub 2017 Oct 11. Nature. 2017. PMID: 29019979 Free PMC article.
Our structure reveals not only the molecular basis of ion conduction but also the unique architecture of TRPMLs, wherein the voltage sensor-like domain is linked to the pore via a cytosolic domain that we term the mucolipin domain. Combined with functional studies, these d …
Our structure reveals not only the molecular basis of ion conduction but also the unique architecture of TRPMLs, wherein the voltage sensor- …
Water corrosion of spent nuclear fuel: radiolysis driven dissolution at the UO2/water interface.
Springell R, Rennie S, Costelle L, Darnbrough J, Stitt C, Cocklin E, Lucas C, Burrows R, Sims H, Wermeille D, Rawle J, Nicklin C, Nuttall W, Scott T, Lander G. Springell R, et al. Among authors: lander g. Faraday Discuss. 2015;180:301-11. doi: 10.1039/c4fd00254g. Faraday Discuss. 2015. PMID: 25932469
A finite element calculation of the highly oxidising hydrogen peroxide product suggests that a more complex surface interaction than simple reaction with H(2)O(2) is responsible for an enhancement in the corrosion rate directly at the interface of water and UO(2), and this may im …
A finite element calculation of the highly oxidising hydrogen peroxide product suggests that a more complex surface interaction than simple …