Generation of islet-like cells from mouse gall bladder by direct ex vivo reprogramming.
Hickey RD, Galivo F, Schug J, Brehm MA, Haft A, Wang Y, Benedetti E, Gu G, Magnuson MA, Shultz LD, Lagasse E, Greiner DL, Kaestner KH, Grompe M.
Hickey RD, et al. Among authors: lagasse e.
Stem Cell Res. 2013 Jul;11(1):503-15. doi: 10.1016/j.scr.2013.02.005. Epub 2013 Feb 18.
Stem Cell Res. 2013.
PMID: 23562832
Free PMC article.
Reprogramming was also enhanced by addition of retinoic acid and inhibition of Notch signaling. Importantly, rGBCs were able to engraft long term in vivo and remained insulin-positive for 15weeks. We conclude that GBCs are a viable source for autologous cell replacement in …
Reprogramming was also enhanced by addition of retinoic acid and inhibition of Notch signaling. Importantly, rGBCs were able to engraft long …