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A Phase III Randomized Study Comparing a Chemotherapy with Cisplatin and Etoposide to a Etoposide Regimen without Cisplatin for Patients with Extensive Small-Cell Lung Cancer.
Berghmans T, Scherpereel A, Meert AP, Giner V, Lecomte J, Lafitte JJ, Leclercq N, Paesmans M, Sculier JP; European Lung Cancer Working Party (ELCWP). Berghmans T, et al. Among authors: lafitte jj. Front Oncol. 2017 Sep 19;7:217. doi: 10.3389/fonc.2017.00217. eCollection 2017. Front Oncol. 2017. PMID: 28975084 Free PMC article.
CLINICAL TRIAL REGISTRATION: https://clinicaltrials.gov/ct2/show/NCT00658580?term=ELCWP+01994&rank=1, identifier NCT00658580....
CLINICAL TRIAL REGISTRATION: https://clinicaltrials.gov/ct2/show/NCT00658580?term=ELCWP+01994&rank=1, identifier NCT00658580....
A phase III randomised study of concomitant induction radiochemotherapy testing two modalities of radiosensitisation by cisplatin (standard versus daily) for limited small-cell lung cancer.
Sculier JP, Lafitte JJ, Efremidis A, Florin MC, Lecomte J, Berchier MC, Richez M, Berghmans T, Scherpereel A, Meert AP, Koumakis G, Leclercq N, Paesmans M, Van Houtte P; European Lung Cancer Working Party (ELCWP). Sculier JP, et al. Among authors: lafitte jj. Ann Oncol. 2008 Oct;19(10):1691-7. doi: 10.1093/annonc/mdn354. Epub 2008 May 25. Ann Oncol. 2008. PMID: 18504252 Free article. Clinical Trial.
CONCLUSION: Induction chemoradiotherapy resulted in both arms in good long-term survival, comparable to the best reported results and without improvement by daily cisplatin administration....
CONCLUSION: Induction chemoradiotherapy resulted in both arms in good long-term survival, comparable to the best reported results and …
Survival is better predicted with a new classification of stage III unresectable non-small cell lung carcinoma treated by chemotherapy and radiotherapy.
Berghmans T, Lafitte JJ, Thiriaux J, VanHoutte P, Lecomte J, Efremidis A, Koumakis G, Giner V, Richez M, Corhay JL, Wackenier P, Lothaire P, Mommen P, Ninane V, Sculier JP; European Lung Cancer Working Party. Berghmans T, et al. Among authors: lafitte jj. Lung Cancer. 2004 Sep;45(3):339-48. doi: 10.1016/j.lungcan.2004.02.016. Lung Cancer. 2004. PMID: 15301874
The classification into stages IIIbeta (T3-4N3M0) and IIIalpha (other TN stage III) better discriminates the patients in term of survival than the 1997 ISS classification....
The classification into stages IIIbeta (T3-4N3M0) and IIIalpha (other TN stage III) better discriminates the patients in term of surv …
[The role of chemotherapy in the treatment of non-metastatic, non-small cell bronchial cancers].
Sculier JP, Berghmans T, Paesmans M, Branle F, Lemaitre F, Mascaux C, Meert AP, Steels E, Vallot F, Lafitte JJ. Sculier JP, et al. Among authors: lafitte jj. Rev Med Brux. 2001 Dec;22(6):477-87. Rev Med Brux. 2001. PMID: 11811043 French.
The methodological assessment has not shown significant difference for quality scores between negative or positive studies in term of survival effect. The aggregation (meta-analysis) shows a significant effect of survival improvement by chemotherapy, whatever all indicatio …
The methodological assessment has not shown significant difference for quality scores between negative or positive studies in term of …
Prophylactic cranial irradiation in small cell lung cancer: a systematic review of the literature with meta-analysis.
Meert AP, Paesmans M, Berghmans T, Martin B, Mascaux C, Vallot F, Verdebout JM, Lafitte JJ, Sculier JP. Meert AP, et al. Among authors: lafitte jj. BMC Cancer. 2001;1:5. doi: 10.1186/1471-2407-1-5. Epub 2001 Jun 19. BMC Cancer. 2001. PMID: 11432756 Free PMC article. Review.
This meta-analysis based on the available published data reveals a decrease of brain metastases incidence (hazard ratio (HR): 0.48; 95 % confidence interval (CI): 0.39 - 0.60) for all the studies and an improvement of survival (HR: 0.82; 95 % CI: 0.71 - 0.96) in patients in CR in …
This meta-analysis based on the available published data reveals a decrease of brain metastases incidence (hazard ratio (HR): 0.48; 95 % con …
Long-term survivors of small-cell lung cancer (SCLC): a French multicenter study. Groupe d'Oncologie de Langue Francaise.
Jacoulet P, Depierre A, Moro D, Rivière A, Milleron B, Quoix E, Ranfaing E, Anthoine D, Lafitte JJ, Lebeau B, Kleisbauer JP, Massin F, Fournel P, Zaegel M, Leclerc JP, Garnier G, Brambilla E, Capron F. Jacoulet P, et al. Among authors: lafitte jj. Ann Oncol. 1997 Oct;8(10):1009-14. doi: 10.1023/a:1008287922285. Ann Oncol. 1997. PMID: 9402175 Free article. Clinical Trial.