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Targeting the tissue factor coagulation initiation complex prevents antiphospholipid antibody development.
Müller-Calleja N, Grunz K, Nguyen TS, Posma J, Pedrosa D, Meineck M, Hollerbach A, Braun J, Muth S, Schild H, Saar K, Hübner N, Krishnaswamy S, Royce J, Teyton L, Lemmermann N, Weinmann-Menke J, Lackner KJ, Ruf W. Müller-Calleja N, et al. Among authors: lackner kj. Blood. 2024 Mar 21;143(12):1167-1180. doi: 10.1182/blood.2023022276. Blood. 2024. PMID: 38142429
Latent infection with murine cytomegalovirus causes TF cytoplasmic domain-dependent development of persistent aPL and circulating phospholipid-reactive B1 cells, which is prevented by short-term intervention with NAPc2 during acute viral infection. In addition, treatment o …
Latent infection with murine cytomegalovirus causes TF cytoplasmic domain-dependent development of persistent aPL and circulating phospholip …
Cardiac troponins - a paradigm for diagnostic biomarker identification and development.
Lackner KJ. Lackner KJ. Clin Chem Lab Med. 2022 Nov 16;61(5):795-800. doi: 10.1515/cclm-2022-1112. Print 2023 Apr 25. Clin Chem Lab Med. 2022. PMID: 36377312 Free article.
The introduction of cardiac troponins into clinical diagnostics has not only improved diagnostic pathways for myocardial infarction but also profoundly influenced the definition of myocardial infarction. The term troponin appeared in the literature almost 60 years ago, i.e …
The introduction of cardiac troponins into clinical diagnostics has not only improved diagnostic pathways for myocardial infarction but also …
Intermittent Fasting-Short- and Long-Term Quality of Life, Fatigue, and Safety in Healthy Volunteers: A Prospective, Clinical Trial.
Anic K, Schmidt MW, Furtado L, Weidenbach L, Battista MJ, Schmidt M, Schwab R, Brenner W, Ruckes C, Lotz J, Lackner KJ, Hasenburg A, Hasenburg A. Anic K, et al. Among authors: lackner kj. Nutrients. 2022 Oct 10;14(19):4216. doi: 10.3390/nu14194216. Nutrients. 2022. PMID: 36235868 Free PMC article.

The results of the WHO-5 questionnaire (15.6 4.6 vs. 18 3.6, p < 0.0019) demonstrated a significant increase in QoL. For long-term QoL six out of eight domains measured by the Short Form Health 36 (SF-36) significantly improved (e.g., physical health: 92.3 11.6 vs. 96.5

…

The results of the WHO-5 questionnaire (15.6 4.6 vs. 18 3.6, p < 0.0019) demonstrated a significant increase in QoL. For long-term

…
Association of birth weight with corneal aberrations in adulthood - Results from a population-based study.
Fieß A, Urschitz MS, Nagler M, Nickels S, Marx-Groß S, Münzel T, Wild PS, Beutel ME, Lackner KJ, Pfeiffer N, Schuster AK. Fieß A, et al. Among authors: lackner kj. J Optom. 2023 Jan-Mar;16(1):42-52. doi: 10.1016/j.optom.2021.06.004. Epub 2022 Jun 25. J Optom. 2023. PMID: 35764478 Free PMC article.
PURPOSE: Low birth weight (BW) is associated with increased corneal aberrations in childhood and alterations of corneal geometry in adulthood. Increased corneal aberrations may be a factor contributing to decreased visual function in former low BW newborns in later life. H …
PURPOSE: Low birth weight (BW) is associated with increased corneal aberrations in childhood and alterations of corneal geometry in a …
Effects of Clopidogrel, Prasugrel and Ticagrelor on Microvascular Function and Platelet Reactivity in Patients With Acute Coronary Syndrome Undergoing Coronary Artery Stenting. A Randomized, Blinded, Parallel Group Trial.
Schnorbus B, Jurk K, Lackner KJ, Welk C, Münzel T, Gori T. Schnorbus B, et al. Among authors: lackner kj. Front Cardiovasc Med. 2021 Dec 13;8:780605. doi: 10.3389/fcvm.2021.780605. eCollection 2021. Front Cardiovasc Med. 2021. PMID: 34966798 Free PMC article.
The microvascular effect was however lost 1 day after stenting and during subsequent follow-up. Further studies are necessary to clarify the the long-term effects and potential benefits of P2Y12 inhibitors on microvascular damage. ...
The microvascular effect was however lost 1 day after stenting and during subsequent follow-up. Further studies are necessary to clarify the …
Rationale and design of the effects of EMpagliflozin on left ventricular DIAstolic function in diabetes (EmDia) study.
Jünger C, Prochaska JH, Gori T, Schulz A, Binder H, Daiber A, Koeck T, Rapp S, Lackner KJ, Münzel T, Wild PS. Jünger C, et al. Among authors: lackner kj. J Cardiovasc Med (Hagerstown). 2022 Mar 1;23(3):191-197. doi: 10.2459/JCM.0000000000001267. J Cardiovasc Med (Hagerstown). 2022. PMID: 34939776 Clinical Trial.
The reduction in cardiovascular mortality and hospitalization due to heart failure might be in part explained by the direct effects of empagliflozin on cardiac diastolic function. The EmDia trial investigates the short-term effects of empagliflozin compared to placebo on t …
The reduction in cardiovascular mortality and hospitalization due to heart failure might be in part explained by the direct effects of empag …
Association of Birth Weight With Foveolar Thickness in Adulthood: Results From a Population-Based Study.
Fieß A, Wagner FM, Urschitz MS, Nagler M, Stoffelns B, Wild PS, Münzel T, Beutel ME, Lackner KJ, Pfeiffer N, Schuster AK. Fieß A, et al. Among authors: lackner kj. Invest Ophthalmol Vis Sci. 2021 Nov 1;62(14):9. doi: 10.1167/iovs.62.14.9. Invest Ophthalmol Vis Sci. 2021. PMID: 34757404 Free PMC article.
PURPOSE: Low birth weight (BW) is associated with alterations of foveal shape development in childhood-leading to an increased retinal thickness of the fovea. The aim of the present study was to assess whether BW has a long-term effect on foveal retinal thickness (R …
PURPOSE: Low birth weight (BW) is associated with alterations of foveal shape development in childhood-leading to an increased retina …
Evaluation of a laboratory-based high-throughput SARS-CoV-2 antigen assay for non-COVID-19 patient screening at hospital admission.
Häuser F, Sprinzl MF, Dreis KJ, Renzaho A, Youhanen S, Kremer WM, Podlech J, Galle PR, Lackner KJ, Rossmann H, Lemmermann NA. Häuser F, et al. Among authors: lackner kj. Med Microbiol Immunol. 2021 Jun;210(2-3):165-171. doi: 10.1007/s00430-021-00706-5. Epub 2021 Apr 15. Med Microbiol Immunol. 2021. PMID: 33856557 Free PMC article.
However, reliable performance data for laboratory-based, high-throughput antigen tests are lacking. Therefore and in response to a short-term shortage of PCR reagents, we evaluated DiaSorin's LIAISON SARS-CoV-2 antigen test in comparison to RT-qPCR, and concerning the appl …
However, reliable performance data for laboratory-based, high-throughput antigen tests are lacking. Therefore and in response to a short- …
Promotion of Arterial Stiffness by Childhood Cancer and Its Characteristics in Adult Long-Term Survivors.
Arnold N, Merzenich H, Wingerter A, Schulz A, Schneider A, Prochaska JH, Göbel S, Neu MA, Henninger N, Panova-Noeva M, Eckerle S, Spix C, Schmidtmann I, Lackner KJ, Beutel ME, Pfeiffer N, Münzel T, Faber J, Wild PS. Arnold N, et al. Among authors: lackner kj. J Am Heart Assoc. 2021 Feb;10(5):e015609. doi: 10.1161/JAHA.119.015609. Epub 2021 Feb 24. J Am Heart Assoc. 2021. PMID: 33624513 Free PMC article.
Background Vascular alterations induced by antineoplastic treatment might be considered as a possible underlying mechanism of increased cardiovascular sequelae in childhood cancer survivors (CCSs). We aimed to evaluate arterial stiffness among long-term CCSs and to compare …
Background Vascular alterations induced by antineoplastic treatment might be considered as a possible underlying mechanism of increased card …
Association of Birth Weight with Peripapillary Retinal Nerve Fiber Layer Thickness in Adulthood-Results from a Population-Based Study.
Fieß A, Nickels S, Urschitz MS, Münzel T, Wild PS, Beutel ME, Lackner KJ, Hoffmann EM, Pfeiffer N, Schuster AK. Fieß A, et al. Among authors: lackner kj. Invest Ophthalmol Vis Sci. 2020 Jul 1;61(8):4. doi: 10.1167/iovs.61.8.4. Invest Ophthalmol Vis Sci. 2020. PMID: 35917383 Free PMC article.
However, to the best of our knowledge, no population-based study has analyzed the relationship of low birth weight to pRNFL thickness in adulthood. The purpose of this study was to investigate whether birth weight has a long-term effect on pRNFL thickness in …
However, to the best of our knowledge, no population-based study has analyzed the relationship of low birth weight to pRNFL thickness …
33 results