Long-term mucosal injury and repair in a murine model of pelvic radiotherapy.
Malipatlolla DK, Patel P, Sjöberg F, Devarakonda S, Kalm M, Angenete E, Lindskog EB, Grandér R, Persson L, Stringer A, Wilderäng U, Swanpalmer J, Kuhn HG, Steineck G, Bull C.
Malipatlolla DK, et al. Among authors: kuhn hg.
Sci Rep. 2019 Sep 24;9(1):13803. doi: 10.1038/s41598-019-50023-4.
Sci Rep. 2019.
PMID: 31551503
Free PMC article.
We then determined the long-term dynamics of mucosal injury, repair, and the duration of inflammation. We show that crypt fission, not cell proliferation, is the main long-term mechanism for rescuing crypt density after irradiation, and provides a potentially wide w …
We then determined the long-term dynamics of mucosal injury, repair, and the duration of inflammation. We show that crypt fission, no …