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Efficacy and safety of three different cumulative doses of intravenous methylprednisolone for moderate to severe and active Graves' orbitopathy.
Bartalena L, Krassas GE, Wiersinga W, Marcocci C, Salvi M, Daumerie C, Bournaud C, Stahl M, Sassi L, Veronesi G, Azzolini C, Boboridis KG, Mourits MP, Soeters MR, Baldeschi L, Nardi M, Currò N, Boschi A, Bernard M, von Arx G; European Group on Graves' Orbitopathy. Bartalena L, et al. Among authors: krassas ge. J Clin Endocrinol Metab. 2012 Dec;97(12):4454-63. doi: 10.1210/jc.2012-2389. Epub 2012 Oct 4. J Clin Endocrinol Metab. 2012. PMID: 23038682 Clinical Trial.
Among patients whose GO improved at 12 wk, 33% in the 7.47-group, 21% in the 4.98-group, and 40% in the 2.25-group had relapsing orbitopathy after glucocorticoid withdrawal at the exploratory 24-wk visit. CONCLUSIONS: The 7.47-g dose provides short-term advantages over low …
Among patients whose GO improved at 12 wk, 33% in the 7.47-group, 21% in the 4.98-group, and 40% in the 2.25-group had relapsing orbitopathy …
Recent concepts of pharmacotherapy and bariatric surgery for childhood obesity: an overview.
Gogakos A, Tzotzas TC, Krassas GE. Gogakos A, et al. Among authors: krassas ge. Pediatr Endocrinol Rev. 2009 Dec;7(2):3-14. Pediatr Endocrinol Rev. 2009. PMID: 20118889 Review.
Only the first two are currently approved by the Food and Drug Administration (FDA) for the long-term treatment of obesity. Safety and efficacy have not been determined beyond 4 years for orlistat and 2 years for sibutramine. ...RYGB is considered a safe and effective opti …
Only the first two are currently approved by the Food and Drug Administration (FDA) for the long-term treatment of obesity. Safety an …
[Selenium and thyroidal function; the role of immunoassays].
Kaprara A, Krassas GE. Kaprara A, et al. Among authors: krassas ge. Hell J Nucl Med. 2006 Sep-Dec;9(3):195-203. Hell J Nucl Med. 2006. PMID: 17160166 Review. Greek, Modern.
Selenium deficiency and disturbed thyroid function may develop under conditions of special dietary regimens, such as long-term total parenteral nutrition or after inadequate nutrition in children. ...
Selenium deficiency and disturbed thyroid function may develop under conditions of special dietary regimens, such as long-term total …
Consequences of an intracranial germ cell-tumor in a young adolescent.
Kaltsas T, Pontikides N, Tsiotsia E, Ramopoulous N, Tsametis C, Samara M, Efthymiou E, Krassas GE. Kaltsas T, et al. Among authors: krassas ge. Pediatr Endocrinol Rev. 2004 Aug;1 Suppl 3:501-4. Pediatr Endocrinol Rev. 2004. PMID: 16444182
The most frequent tumors arise in the pineal and suprasellar region. The long-term consequences of these tumors have not been very well characterized, as few series with a limited number of patients have reported on the neuro-endocrine development and quality of life of th …
The most frequent tumors arise in the pineal and suprasellar region. The long-term consequences of these tumors have not been very we …
Gonadal effect of radiation from 131I in male patients with thyroid carcinoma.
Krassas GE, Pontikides N. Krassas GE, et al. Arch Androl. 2005 May-Jun;51(3):171-5. doi: 10.1080/014850190898746. Arch Androl. 2005. PMID: 16025855 Review.
In all young male patients, but especially in those with metastatic or pelvic disease or both, the long-term storage of semen should be addressed prior to therapy. Sperm banking should be considered in patients likely to be given cumulative doses greater than 14 GBq of 131 …
In all young male patients, but especially in those with metastatic or pelvic disease or both, the long-term storage of semen should …
Treatment of juvenile Graves' disease and its ophthalmic complication: the 'European way'.
Krassas GE. Krassas GE. Eur J Endocrinol. 2004 Apr;150(4):407-14. doi: 10.1530/eje.0.1500407. Eur J Endocrinol. 2004. PMID: 15080767 Review.
Given the considerable increase in the risk of thyroid cancer in young children exposed to external radiation, it has been hypothesized that there may be a small increase in the risk of thyroid cancer in young children treated with RAI. Until long-term data on safety are a …
Given the considerable increase in the risk of thyroid cancer in young children exposed to external radiation, it has been hypothesized that …
Clinical and endocrine responses to pituitary radiotherapy in pediatric Cushing's disease: an effective second-line treatment.
Storr HL, Plowman PN, Carroll PV, François I, Krassas GE, Afshar F, Besser GM, Grossman AB, Savage MO. Storr HL, et al. Among authors: krassas ge. J Clin Endocrinol Metab. 2003 Jan;88(1):34-7. doi: 10.1210/jc.2002-021032. J Clin Endocrinol Metab. 2003. PMID: 12519825
In conclusion, pituitary RT is an effective and relatively rapid-onset treatment for pediatric CD after failure of TSS. GH deficiency occurred in 86% patients. Long-term follow-up suggests some recovery of GH secretion and preservation of other anterior pituitary function. …
In conclusion, pituitary RT is an effective and relatively rapid-onset treatment for pediatric CD after failure of TSS. GH deficiency occurr …
Cabergoline as a first-line treatment in newly diagnosed macroprolactinomas.
Pontikides N, Krassas GE, Nikopoulou E, Kaltsas T. Pontikides N, et al. Among authors: krassas ge. Pituitary. 2000 May;2(4):277-81. doi: 10.1023/a:1009913200542. Pituitary. 2000. PMID: 11081149 Clinical Trial.
There are few long-term studies of cabergoline (CAB) administration in patients with macroprolactinomas. ...This remarkable improvement was associated with an excellent tolerability of the long-term treatment due to the low incidence of side effects. In conclusion, …
There are few long-term studies of cabergoline (CAB) administration in patients with macroprolactinomas. ...This remarkable improveme …