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GLP-1 agonists: A review for emergency clinicians.
Long B, Pelletier J, Koyfman A, Bridwell RE. Long B, et al. Among authors: koyfman a. Am J Emerg Med. 2024 Apr;78:89-94. doi: 10.1016/j.ajem.2024.01.010. Epub 2024 Jan 12. Am J Emerg Med. 2024. PMID: 38241775 Review.
The two most common agents include subcutaneous semaglutide (Ozempic, approved for type 2 diabetes, and Wegovy, approved for weight loss) and liraglutide (Saxenda, approved for weight loss, and Victoza, approved for type 2 diabetes), though an oral formulation of semaglutide is a …
The two most common agents include subcutaneous semaglutide (Ozempic, approved for type 2 diabetes, and Wegovy, approved for weight loss) an …
Ebola virus disease: A review for the emergency medicine clinician.
Chavez S, Koyfman A, Gottlieb M, Brady WJ, Carius BM, Liang SY, Long B. Chavez S, et al. Among authors: koyfman a. Am J Emerg Med. 2023 Aug;70:30-40. doi: 10.1016/j.ajem.2023.04.037. Epub 2023 Apr 29. Am J Emerg Med. 2023. PMID: 37196593 Review.
Survivors of the disease may have a complicated recovery, marked by long-term symptoms. CONCLUSION: EVD is a potentially deadly condition that can present with a wide range of signs and symptoms. ...
Survivors of the disease may have a complicated recovery, marked by long-term symptoms. CONCLUSION: EVD is a potentially deadly condi …
Pulmonary arterial hypertension in the emergency department: A focus on medication management.
Barlow A, Barlow B, Koyfman A, Long B, Bissell B. Barlow A, et al. Among authors: koyfman a. Am J Emerg Med. 2021 Sep;47:101-108. doi: 10.1016/j.ajem.2021.03.072. Epub 2021 Mar 26. Am J Emerg Med. 2021. PMID: 33794472 Review.
With over five drug classes FDA approved in the last decade, the significant advancements in the pharmacologic management of PAH has improved long-term outcomes. Drug therapies have been developed to directly target the underlying pathogenesis of PAH including phosphodiest …
With over five drug classes FDA approved in the last decade, the significant advancements in the pharmacologic management of PAH has improve …
A primer for managing cardiac transplant patients in the emergency department setting.
Long B, Brady WJ, Gragossian A, Koyfman A, Gottlieb M. Long B, et al. Among authors: koyfman a. Am J Emerg Med. 2021 Mar;41:130-138. doi: 10.1016/j.ajem.2020.12.071. Epub 2021 Jan 1. Am J Emerg Med. 2021. PMID: 33440325 Review.
BACKGROUND: Cardiac transplant is an effective long-term management option for several severe cardiac diseases. These cardiac transplant patients may present to the emergency department with a range of issues involving the cardiac transplantation, including complications d …
BACKGROUND: Cardiac transplant is an effective long-term management option for several severe cardiac diseases. These cardiac transpl …
Emergent Complications of Rheumatoid Arthritis.
Berman S, Bucher J, Koyfman A, Long BJ. Berman S, et al. Among authors: koyfman a. J Emerg Med. 2018 Nov;55(5):647-658. doi: 10.1016/j.jemermed.2018.07.030. Epub 2018 Sep 22. J Emerg Med. 2018. PMID: 30253957 Review.
It is not necessarily the role of the clinician to diagnose RA in its earliest phases or initiate long-term immunosuppressive therapy from the emergency department; however, detection of some of the disease's characteristics can lead to earlier referral to specialists to b …
It is not necessarily the role of the clinician to diagnose RA in its earliest phases or initiate long-term immunosuppressive therapy …
Alternative Treatment Options for Atrioventricular-Nodal-Reentry Tachycardia: An Emergency Medicine Review.
Brubaker S, Long B, Koyfman A. Brubaker S, et al. Among authors: koyfman a. J Emerg Med. 2018 Feb;54(2):198-206. doi: 10.1016/j.jemermed.2017.10.003. Epub 2017 Nov 26. J Emerg Med. 2018. PMID: 29239759 Review.
Recent literature suggests that nondihydropyridine calcium channel blockers, such as verapamil and diltiazem, may be as effective as adenosine, without the negative short-term side effects. Multiple studies have demonstrated that although adenosine is rapid acting, there i …
Recent literature suggests that nondihydropyridine calcium channel blockers, such as verapamil and diltiazem, may be as effective as adenosi …
Clinical Mimics: An Emergency Medicine-Focused Review of Influenza Mimics.
Simon E, Long B, Koyfman A. Simon E, et al. Among authors: koyfman a. J Emerg Med. 2017 Jul;53(1):49-65. doi: 10.1016/j.jemermed.2016.12.013. Epub 2017 Feb 16. J Emerg Med. 2017. PMID: 28215397 Free PMC article. Review.
High-risk populations include children younger than 4 years, adults older than 50 years, adults with immunosuppression or chronic comorbidities, pregnancy, obesity, residents of long-term care facilities, and several others. The Centers for Disease Control and Prevention r …
High-risk populations include children younger than 4 years, adults older than 50 years, adults with immunosuppression or chronic comorbidit …
Best Clinical Practice: Controversies in Transient Ischemic Attack Evaluation and Disposition in the Emergency Department.
Long B, Koyfman A. Long B, et al. Among authors: koyfman a. J Emerg Med. 2017 Mar;52(3):299-310. doi: 10.1016/j.jemermed.2016.10.024. Epub 2016 Nov 19. J Emerg Med. 2017. PMID: 27876328
The American College of Emergency Physicians provides a Level B Recommendation for the use of rapid diagnostic protocols to determine patient short-term risk for stroke while avoiding the reliance on stratification instruments to discharge patients from the ED....
The American College of Emergency Physicians provides a Level B Recommendation for the use of rapid diagnostic protocols to determine patien …
Current Controversies in Thrombolytic Use in Acute Pulmonary Embolism.
Long B, Koyfman A. Long B, et al. Among authors: koyfman a. J Emerg Med. 2016 Jul;51(1):37-44. doi: 10.1016/j.jemermed.2016.02.024. Epub 2016 Apr 9. J Emerg Med. 2016. PMID: 27071316
Although significant study heterogeneity exists, thrombolytics can improve long-term outcomes, with decreased bleeding risk with half-dose thrombolytics and catheter-directed treatments. ...The risks, including major hemorrhage, and benefits, primarily improved long-ter …
Although significant study heterogeneity exists, thrombolytics can improve long-term outcomes, with decreased bleeding risk with half …
Enhancing the Magnitude of Antibody Responses through Biomaterial Stereochemistry.
Appavu R, Chesson CB, Koyfman AY, Snook JD, Kohlhapp FJ, Zloza A, Rudra JS. Appavu R, et al. Among authors: koyfman ay. ACS Biomater Sci Eng. 2015 Jul 13;1(7):601-609. doi: 10.1021/acsbiomaterials.5b00139. Epub 2015 Jun 12. ACS Biomater Sci Eng. 2015. PMID: 33434976
In mice, d-amino acid peptide nanofibers displaying OVA elicited stronger antibody responses, equivalent levels of CD4+ T cell responses, and long-term antigen-presentation in vivo compared to l-amino acid nanofibers. ...
In mice, d-amino acid peptide nanofibers displaying OVA elicited stronger antibody responses, equivalent levels of CD4+ T cell responses, an …