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In Vivo Estimation of the Biological Effects of Endocrine Disruptors in Rabbits after Combined and Long-Term Exposure: Study Protocol.
Karzi V, Tzatzarakis MN, Alegakis A, Vakonaki E, Fragkiadoulaki I, Kaloudis K, Chalkiadaki C, Apalaki P, Panagiotopoulou M, Kalliantasi A, Kouretas D, Docea AO, Calina D, Tsatsakis A. Karzi V, et al. Among authors: kouretas d. Toxics. 2022 May 12;10(5):246. doi: 10.3390/toxics10050246. Toxics. 2022. PMID: 35622659 Free PMC article.
A Mixture of Endocrine Disruptors and the Pesticide Roundup() Induce Oxidative Stress in Rabbit Liver When Administered under the Long-Term Low-Dose Regimen: Reinforcing the Notion of Real-Life Risk Simulation.
Vardakas P, Veskoukis AS, Rossiou D, Gournikis C, Kapetanopoulou T, Karzi V, Docea AO, Tsatsakis A, Kouretas D. Vardakas P, et al. Among authors: kouretas d. Toxics. 2022 Apr 14;10(4):190. doi: 10.3390/toxics10040190. Toxics. 2022. PMID: 35448451 Free PMC article.
Humans are exposed to xenobiotic mixtures daily through the long-term, low-dose regimen. Investigations designed to simulate this exposure profile approach the real-life risk simulation (RLRS) idea of modern toxicology. ...Indeed, the administration of the EDs mixture and …
Humans are exposed to xenobiotic mixtures daily through the long-term, low-dose regimen. Investigations designed to simulate this exp …
Fasting-mediated metabolic and toxicity reprogramming impacts circulating microRNA levels in humans.
Ravanidis S, Grundler F, de Toledo FW, Dimitriou E, Tekos F, Skaperda Z, Kouretas D, Doxakis E. Ravanidis S, et al. Among authors: kouretas d. Food Chem Toxicol. 2021 Jun;152:112187. doi: 10.1016/j.fct.2021.112187. Epub 2021 Apr 8. Food Chem Toxicol. 2021. PMID: 33839215
It is well-established that long-term fasting improves metabolic health, enhances the total antioxidant capacity and increases well-being. ...Overall, these data are consistent with a model in which long-term fasting engages homeostatic mechanisms associated with sp …
It is well-established that long-term fasting improves metabolic health, enhances the total antioxidant capacity and increases well-b …
Improved strategies to counter the COVID-19 pandemic: Lockdowns vs. primary and community healthcare.
Farsalinos K, Poulas K, Kouretas D, Vantarakis A, Leotsinidis M, Kouvelas D, Docea AO, Kostoff R, Gerotziafas GT, Antoniou MN, Polosa R, Barbouni A, Yiakoumaki V, Giannouchos TV, Bagos PG, Lazopoulos G, Izotov BN, Tutelyan VA, Aschner M, Hartung T, Wallace HM, Carvalho F, Domingo JL, Tsatsakis A. Farsalinos K, et al. Among authors: kouretas d. Toxicol Rep. 2021;8:1-9. doi: 10.1016/j.toxrep.2020.12.001. Epub 2020 Dec 3. Toxicol Rep. 2021. PMID: 33294384 Free PMC article.
This, together with more selective social distancing measures (instead of horizontal lockdowns), represents the only viable and realistic long-term strategy for COVID-19 pandemic mitigation....
This, together with more selective social distancing measures (instead of horizontal lockdowns), represents the only viable and realistic lo …
The flavoring and not the nicotine content is a decisive factor for the effects of refill liquids of electronic cigarette on the redox status of endothelial cells.
Kerasioti E, Veskoukis AS, Skaperda Z, Zacharias A, Poulas K, Lazopoulos G, Kouretas D. Kerasioti E, et al. Among authors: kouretas d. Toxicol Rep. 2020 Sep 1;7:1095-1102. doi: 10.1016/j.toxrep.2020.08.029. eCollection 2020. Toxicol Rep. 2020. PMID: 32953462 Free PMC article.
Although the acute effects of electronic cigarette use have been extensively studied, the long-term potential adverse effects on human health remain largely unknown. ...
Although the acute effects of electronic cigarette use have been extensively studied, the long-term potential adverse effects on huma …
Interplay between oxidative damage, the redox status, and metabolic biomarkers during long-term fasting.
Grundler F, Mesnage R, Goutzourelas N, Tekos F, Makri S, Brack M, Kouretas D, Wilhelmi de Toledo F. Grundler F, et al. Among authors: kouretas d. Food Chem Toxicol. 2020 Nov;145:111701. doi: 10.1016/j.fct.2020.111701. Epub 2020 Aug 25. Food Chem Toxicol. 2020. PMID: 32858131 Free PMC article.
In conclusion, it was demonstrated that long-term fasting enhanced the endogenous production of antioxidant molecules, that act protectively against free radicals, and in parallel improved the metabolic health status. Our results suggest that the outcome of long-term
In conclusion, it was demonstrated that long-term fasting enhanced the endogenous production of antioxidant molecules, that act prote …
Analysis of the intricate effects of polyunsaturated fatty acids and polyphenols on inflammatory pathways in health and disease.
Margină D, Ungurianu A, Purdel C, Nițulescu GM, Tsoukalas D, Sarandi E, Thanasoula M, Burykina TI, Tekos F, Buha A, Nikitovic D, Kouretas D, Tsatsakis AM. Margină D, et al. Among authors: kouretas d. Food Chem Toxicol. 2020 Sep;143:111558. doi: 10.1016/j.fct.2020.111558. Epub 2020 Jul 5. Food Chem Toxicol. 2020. PMID: 32640331 Free PMC article. Review.
In the present manuscript we have reviewed scientific data from recent publications regarding the beneficial cellular and molecular effects induced by dietary plant products, mainly polyphenolic compounds and PUFAs, and summarize the clinical outcomes expected from these types of …
In the present manuscript we have reviewed scientific data from recent publications regarding the beneficial cellular and molecular effects …
Influence of Long-Term Fasting on Blood Redox Status in Humans.
Wilhelmi de Toledo F, Grundler F, Goutzourelas N, Tekos F, Vassi E, Mesnage R, Kouretas D. Wilhelmi de Toledo F, et al. Among authors: kouretas d. Antioxidants (Basel). 2020 Jun 6;9(6):496. doi: 10.3390/antiox9060496. Antioxidants (Basel). 2020. PMID: 32517172 Free PMC article.
Changes in blood redox status, linked to the development of a variety of metabolic diseases, have been recently documented during calorie restriction and intermittent fasting, but not with long-term fasting (LF). We investigated some parameters of the blood redox profile i …
Changes in blood redox status, linked to the development of a variety of metabolic diseases, have been recently documented during calorie re …
Approaching reactive species in the frame of their clinical significance: A toxicological appraisal.
Veskoukis AS, Tsatsakis A, Kouretas D. Veskoukis AS, et al. Among authors: kouretas d. Food Chem Toxicol. 2020 Apr;138:111206. doi: 10.1016/j.fct.2020.111206. Epub 2020 Feb 28. Food Chem Toxicol. 2020. PMID: 32113950 Review.
These are related to the real-life exposure scenario via the regimen of long-term low-dose (far below NOAEL) exposure to mixtures of xenobiotics and can potentially offer perspectives in order to investigate in depth whether or not reactive species can be introduced as cli …
These are related to the real-life exposure scenario via the regimen of long-term low-dose (far below NOAEL) exposure to mixtures of …
Prediction of Antioxidant Activity of Cherry Fruits from UAS Multispectral Imagery Using Machine Learning.
Karydas C, Iatrou M, Kouretas D, Patouna A, Iatrou G, Lazos N, Gewehr S, Tseni X, Tekos F, Zartaloudis Z, Mainos E, Mourelatos S. Karydas C, et al. Among authors: kouretas d. Antioxidants (Basel). 2020 Feb 14;9(2):156. doi: 10.3390/antiox9020156. Antioxidants (Basel). 2020. PMID: 32075036 Free PMC article.
It could also support site-specific treatments (precision farming) for improving fruit quality in the long-term, with analogous marketing perspectives....
It could also support site-specific treatments (precision farming) for improving fruit quality in the long-term, with analogous marke …
27 results