Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

8 results

Filters applied: . Clear all
Page 1
Clinical indicators useful in decision-making about palliative chemotherapy for end-of-life ovarian cancer patients.
Kiuchi K, Hasegawa K, Watanabe M, Motegi E, Kosaka N, Fukasawa I. Kiuchi K, et al. Among authors: kosaka n. Arch Gynecol Obstet. 2022 Feb;305(2):425-430. doi: 10.1007/s00404-021-06162-z. Epub 2021 Aug 4. Arch Gynecol Obstet. 2022. PMID: 34347151
We evaluated whether active palliative chemotherapy is beneficial for such patients using inflammatory parameters, nutritional indicators, and the PPI (Palliative Prognostic Index), which predicts short-term prognosis. METHODS: Thirty-six patients among 49 patients who die …
We evaluated whether active palliative chemotherapy is beneficial for such patients using inflammatory parameters, nutritional indicators, a …
Ongoing repair of migration-coupled DNA damage allows planarian adult stem cells to reach wound sites.
Sahu S, Sridhar D, Abnave P, Kosaka N, Dattani A, Thompson JM, Hill MA, Aboobaker A. Sahu S, et al. Among authors: kosaka n. Elife. 2021 Apr 23;10:e63779. doi: 10.7554/eLife.63779. Elife. 2021. PMID: 33890575 Free PMC article.
Our findings reveal that migration of normal stem cells in vivo represents an unappreciated source of damage, which could be a significant source of mutations in animals during development or during long-term tissue homeostasis....
Our findings reveal that migration of normal stem cells in vivo represents an unappreciated source of damage, which could be a significant s …
Confirmation of the sterilization effect using a high concentration of ozone gas for the bio-clean room.
Iwamura T, Nagano K, Nogami T, Matsuki N, Kosaka N, Shintani H, Katoh M. Iwamura T, et al. Among authors: kosaka n. Biocontrol Sci. 2013;18(1):9-20. doi: 10.4265/bio.18.9. Biocontrol Sci. 2013. PMID: 23538847 Free article.
Blow vents and suction ports were placed to ensure a uniform airflow which would extend through the entire room during ozone gas sterilization. Tests regarding long-term material exposure to ozone gas were conducted when the system was introduced to distinguish usable and …
Blow vents and suction ports were placed to ensure a uniform airflow which would extend through the entire room during ozone gas sterilizati …
Stilbene derivatives promote Ago2-dependent tumour-suppressive microRNA activity.
Hagiwara K, Kosaka N, Yoshioka Y, Takahashi RU, Takeshita F, Ochiya T. Hagiwara K, et al. Among authors: kosaka n. Sci Rep. 2012;2:314. doi: 10.1038/srep00314. Epub 2012 Mar 15. Sci Rep. 2012. PMID: 22423322 Free PMC article.
Most importantly, resveratrol-induced Ago2 resulted in a long-term gene silencing response. We also found that pterostilbene, which is a natural dimethylated resveratrol analogue, is capable of mediating Ago2-dependent anti-cancer activity in a manner mechanistically simil …
Most importantly, resveratrol-induced Ago2 resulted in a long-term gene silencing response. We also found that pterostilbene, which i …
Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo.
Minakuchi Y, Takeshita F, Kosaka N, Sasaki H, Yamamoto Y, Kouno M, Honma K, Nagahara S, Hanai K, Sano A, Kato T, Terada M, Ochiya T. Minakuchi Y, et al. Among authors: kosaka n. Nucleic Acids Res. 2004 Jul 22;32(13):e109. doi: 10.1093/nar/gnh093. Nucleic Acids Res. 2004. PMID: 15272050 Free PMC article.
Accordingly, we describe here that Atelocollagen complexed with siRNA is resistant to nucleases and is efficiently transduced into cells, thereby allowing long-term gene silencing. Site-specific in vivo administration of an anti-luciferase siRNA/Atelocollagen complex reduc …
Accordingly, we describe here that Atelocollagen complexed with siRNA is resistant to nucleases and is efficiently transduced into cells, th …
Long-term effects nasal continuous positive airway pressure on daytime sleepiness, mood and traffic accidents in patients with obstructive sleep apnoea.
Yamamoto H, Akashiba T, Kosaka N, Ito D, Horie T. Yamamoto H, et al. Among authors: kosaka n. Respir Med. 2000 Jan;94(1):87-90. doi: 10.1053/rmed.1999.0698. Respir Med. 2000. PMID: 10714485 Free article.
To describe the long-term effects of nasal continuous positive airway pressure (CPAP) on the rate of traffic car accidents, excessive daytime sleepiness (EDS) and mood in patients with obstructive sleep apnoea syndrome (OSAS), we investigated the changes of these parameter …
To describe the long-term effects of nasal continuous positive airway pressure (CPAP) on the rate of traffic car accidents, excessive …
[Long-term effects of nasal continuous positive airway pressure on pulmonary function and blood gas data in patients with obstructive sleep apnea syndrome].
Kosaka N, Akashiba T, Minemura H, Yamamoto H, Horie T. Kosaka N, et al. Nihon Kokyuki Gakkai Zasshi. 1998 Dec;36(12):1011-6. Nihon Kokyuki Gakkai Zasshi. 1998. PMID: 10064953 Clinical Trial. Japanese.
To evaluate the long-term effects of nasal continuous positive airway pressure (NCPAP) on pulmonary function and blood gas levels in patients with obstructive sleep apnea syndrome (OSAS), we examined the pulmonary functions and blood gases in 25 male patients with OSAS bef …
To evaluate the long-term effects of nasal continuous positive airway pressure (NCPAP) on pulmonary function and blood gas levels in …