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Co-occurrence of IgA nephropathy and IgG4-Tubulointersitial nephritis effectively treated with tacrolimus: a case report.
Tian M, Luan J, Jiao C, Chang Q, Kopp JB, Zhou H. Tian M, et al. Among authors: kopp jb. BMC Nephrol. 2021 Aug 12;22(1):279. doi: 10.1186/s12882-021-02477-w. BMC Nephrol. 2021. PMID: 34384379 Free PMC article.
Glucocorticoids are recommended as the first-line therapy for IgG4-TIN. The use of tacrolimus as a long-term maintenance treatment has not been described. We report the case of a man who developed IgAN and IgG4-TIN without abnormalities in extra-renal tissue, without renal …
Glucocorticoids are recommended as the first-line therapy for IgG4-TIN. The use of tacrolimus as a long-term maintenance treatment ha …
Genetic Testing in Clinical Settings.
Franceschini N, Frick A, Kopp JB. Franceschini N, et al. Among authors: kopp jb. Am J Kidney Dis. 2018 Oct;72(4):569-581. doi: 10.1053/j.ajkd.2018.02.351. Epub 2018 Apr 11. Am J Kidney Dis. 2018. PMID: 29655499 Free PMC article. Review.
Because our understanding of genetic factors associated with disease and drug response is rapidly increasing and new genetic tests are being developed that could be adopted by clinicians in the short term, we also provide extensive resources for information and education o …
Because our understanding of genetic factors associated with disease and drug response is rapidly increasing and new genetic tests are being …
Rethinking hypertensive kidney disease: arterionephrosclerosis as a genetic, metabolic, and inflammatory disorder.
Kopp JB. Kopp JB. Curr Opin Nephrol Hypertens. 2013 May;22(3):266-72. doi: 10.1097/MNH.0b013e3283600f8c. Curr Opin Nephrol Hypertens. 2013. PMID: 23470819 Free PMC article. Review.
It may be time to use the established, etiologically neutral term, arterionephrosclerosis, to consider whether this is a disease rather than a pathologic description, and to determine the causal role of various clinical correlates including aging, obesity, hyperlipidemia, …
It may be time to use the established, etiologically neutral term, arterionephrosclerosis, to consider whether this is a disease rath …
Recent progress in the pathophysiology and treatment of FSGS recurrence.
Cravedi P, Kopp JB, Remuzzi G. Cravedi P, et al. Among authors: kopp jb. Am J Transplant. 2013 Feb;13(2):266-74. doi: 10.1111/ajt.12045. Epub 2013 Jan 11. Am J Transplant. 2013. PMID: 23312002 Free PMC article. Review.
Focal segmental glomerulosclerosis (FSGS) is a glomerular disease characterized by proteinuria, frequent progression to end-stage renal disease, and recurrence after kidney transplantation in 25% of patients, which negatively impacts long-term allograft survival. Experimen …
Focal segmental glomerulosclerosis (FSGS) is a glomerular disease characterized by proteinuria, frequent progression to end-stage renal dise …
Longitudinal assessment of metabolic abnormalities in adolescents and young adults with HIV-infection acquired perinatally or in early childhood.
Dimock D, Thomas V, Cushing A, Purdy JB, Worrell C, Kopp JB, Hazra R, Hadigan C. Dimock D, et al. Among authors: kopp jb. Metabolism. 2011 Jun;60(6):874-80. doi: 10.1016/j.metabol.2010.08.007. Epub 2010 Oct 13. Metabolism. 2011. PMID: 20947103 Free PMC article.
Impaired glucose tolerance, insulin resistance, dyslipidemia, and microalbuminuria are common among young adults with HIV. Long-term exposure to therapy may translate into substantial persistent metabolic risk....
Impaired glucose tolerance, insulin resistance, dyslipidemia, and microalbuminuria are common among young adults with HIV. Long-term …
Pirfenidone: an anti-fibrotic therapy for progressive kidney disease.
Cho ME, Kopp JB. Cho ME, et al. Among authors: kopp jb. Expert Opin Investig Drugs. 2010 Feb;19(2):275-83. doi: 10.1517/13543780903501539. Expert Opin Investig Drugs. 2010. PMID: 20050822 Free PMC article. Review.
TAKE HOME MESSAGE: Because many of the available clinical trials have been small and/or uncontrolled, conclusive evidence regarding efficacy and safety of pirfenidone is lacking, particularly in patients with renal or hepatic dysfunction. Larger studies are needed to better under …
TAKE HOME MESSAGE: Because many of the available clinical trials have been small and/or uncontrolled, conclusive evidence regarding efficacy …
Conditionally immortalized human podocyte cell lines established from urine.
Sakairi T, Abe Y, Kajiyama H, Bartlett LD, Howard LV, Jat PS, Kopp JB. Sakairi T, et al. Among authors: kopp jb. Am J Physiol Renal Physiol. 2010 Mar;298(3):F557-67. doi: 10.1152/ajprenal.00509.2009. Epub 2009 Dec 2. Am J Physiol Renal Physiol. 2010. PMID: 19955187 Free PMC article.
To determine the phenotypic characteristics of viable urinary cells derived from human subjects, we established long-term urinary cell culture from two patients with focal segmental glomerulosclerosis and two healthy volunteers, via transformation with the thermosensitive …
To determine the phenotypic characteristics of viable urinary cells derived from human subjects, we established long-term urinary cel …
HIV and the kidney: a status report after 20 years.
Cho ME, Kopp JB. Cho ME, et al. Among authors: kopp jb. Curr HIV/AIDS Rep. 2004 Sep;1(3):109-15. doi: 10.1007/s11904-004-0016-9. Curr HIV/AIDS Rep. 2004. PMID: 16091230 Review.
Long-term sun exposure alters the collagen of the papillary dermis. Comparison of sun-protected and photoaged skin by northern analysis, immunohistochemical staining, and confocal laser scanning microscopy.
Bernstein EF, Chen YQ, Kopp JB, Fisher L, Brown DB, Hahn PJ, Robey FA, Lakkakorpi J, Uitto J. Bernstein EF, et al. Among authors: kopp jb. J Am Acad Dermatol. 1996 Feb;34(2 Pt 1):209-18. doi: 10.1016/s0190-9622(96)80114-9. J Am Acad Dermatol. 1996. PMID: 8642084
BACKGROUND: Long-term solar irradiation produces both morphologic and functional changes in affected skin. ...OBJECTIVE: Our purpose was to investigate alterations in the production and morphology of collagen fibers brought about by long-term sun exposure. METHODS: …
BACKGROUND: Long-term solar irradiation produces both morphologic and functional changes in affected skin. ...OBJECTIVE: Our purpose …