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JAK1 inhibitors for the treatment of atopic dermatitis: a focus on pharmacokinetic considerations.
Kopelman H, Kontzias C, Alihosseni C, Feldman SR. Kopelman H, et al. Expert Opin Drug Metab Toxicol. 2023 Jul-Dec;19(8):537-542. doi: 10.1080/17425255.2023.2256227. Epub 2023 Sep 11. Expert Opin Drug Metab Toxicol. 2023. PMID: 37695699 Review.
While JAK1 inhibitors appear to be safe, they were only recently approved for AD in January 2022, and more long-term safety data is needed. We expect to see additional FDA approval of these drugs, new formulations, and more safety and efficacy data in the future....
While JAK1 inhibitors appear to be safe, they were only recently approved for AD in January 2022, and more long-term safety data is n …
Avacopan for the Treatment of Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis.
Alihosseini C, Kopelman H, Zaino M, Feldman SR. Alihosseini C, et al. Among authors: kopelman h. Ann Pharmacother. 2023 Dec;57(12):1449-1454. doi: 10.1177/10600280231161592. Epub 2023 Mar 28. Ann Pharmacother. 2023. PMID: 36975183 Review.
RELEVANCE TO PATIENT CARE AND CLINICAL PRACTICE IN COMPARISON WITH EXISTING DRUGS: Glucocorticoids in combination with cyclophosphamide, azathioprine, and/or rituximab have been a mainstay of ANCA-associated vasculitis treatment. However, short- and long-term medication-re …
RELEVANCE TO PATIENT CARE AND CLINICAL PRACTICE IN COMPARISON WITH EXISTING DRUGS: Glucocorticoids in combination with cyclophosphamide, aza …
Slow pathway catheter ablation of atrioventricular nodal re-entrant tachycardia guided by electroanatomical mapping: a randomized comparison to the conventional approach.
Kopelman HA, Prater SP, Tondato F, Chronos NA, Peters NS. Kopelman HA, et al. Europace. 2003 Apr;5(2):171-4. doi: 10.1053/eupc.2002.0296. Europace. 2003. PMID: 12633642 Clinical Trial.
Electroanatomical mapping was associated with a lower number (2.7+/-1.6 vs 5+/-2.8; P=0.018), duration (165.3+/-181.6 vs 341+/-177.7s; P=0.013), and total energy delivery (24.3+/-3.1 vs 28.7+/-4.5 watts; P=0.042) of RF applications. There were no acute or long-term (8.9+/- …
Electroanatomical mapping was associated with a lower number (2.7+/-1.6 vs 5+/-2.8; P=0.018), duration (165.3+/-181.6 vs 341+/-177.7s; P=0.0 …
Long-term follow-up of patients requiring intravenous amiodarone to suppress hemodynamically destabilizing ventricular arrhythmias.
Fogel RI, Herre JM, Kopelman HA, Kowey PR, Trohman RG, Fineberg N, Prystowsky EN. Fogel RI, et al. Among authors: kopelman ha. Am Heart J. 2000 Apr;139(4):690-5. doi: 10.1016/s0002-8703(00)90049-8. Am Heart J. 2000. PMID: 10740153
BACKGROUND: Intravenous amiodarone is effective for the acute suppression of recurrent hemodynamically destabilizing ventricular arrhythmias. There are no follow-up data on patients undergoing long-term therapy with intravenous amiodarone. The objective of this investigati …
BACKGROUND: Intravenous amiodarone is effective for the acute suppression of recurrent hemodynamically destabilizing ventricular arrhythmias …