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Functional capacity and dyspnea during follow-up after acute pulmonary embolism.
Farmakis IT, Valerio L, Barco S, Christodoulou KC, Ewert R, Giannakoulas G, Held M, Hobohm L, Keller K, Wilkens H, Rosenkranz S, Konstantinides SV. Farmakis IT, et al. Among authors: konstantinides sv. J Thromb Haemost. 2024 Jan;22(1):163-171. doi: 10.1016/j.jtha.2023.08.024. Epub 2023 Aug 29. J Thromb Haemost. 2024. PMID: 37652350
BACKGROUND: Dissecting the determinants of functional capacity during long-term follow-up after acute pulmonary embolism (PE) can help to better characterize a patient population with persisting limitation. ...Abnormal 6MWD predicted subsequent post-pulmonary embolism impa …
BACKGROUND: Dissecting the determinants of functional capacity during long-term follow-up after acute pulmonary embolism (PE) can hel …
Social determinants of health in pulmonary embolism management and outcome in hospitals: Insights from the United States nationwide inpatient sample.
Farmakis IT, Valerio L, Giannakoulas G, Hobohm L, Cushman M, Piazza G, Konstantinides SV, Barco S. Farmakis IT, et al. Among authors: konstantinides sv. Res Pract Thromb Haemost. 2023 Apr 6;7(3):100147. doi: 10.1016/j.rpth.2023.100147. eCollection 2023 Mar. Res Pract Thromb Haemost. 2023. PMID: 37181280 Free PMC article.
Low socioeconomic status was also associated with lesser use of advanced treatment modalities and greater in-hospital mortality. Future studies should further explore and consider the long-term impact of social inequities in PE management....
Low socioeconomic status was also associated with lesser use of advanced treatment modalities and greater in-hospital mortality. Future stud …
Clinical profile and outcome of isolated pulmonary embolism: a systematic review and meta-analysis.
Ten Cate V, Prochaska JH, Schulz A, Nagler M, Robles AP, Jurk K, Koeck T, Rapp S, Düber C, Münzel T, Konstantinides SV, Wild PS. Ten Cate V, et al. Among authors: konstantinides sv. EClinicalMedicine. 2023 Apr 27;59:101973. doi: 10.1016/j.eclinm.2023.101973. eCollection 2023 May. EClinicalMedicine. 2023. PMID: 37152363 Free PMC article.
INTERPRETATION: Our findings suggest that isolated PE appears to be a specific entity that may signal a long-term risk of arterial thrombosis. Randomised controlled trials are necessary to establish whether alternative treatment regimens are beneficial for this patient sub …
INTERPRETATION: Our findings suggest that isolated PE appears to be a specific entity that may signal a long-term risk of arterial th …
Cardiopulmonary exercise testing during follow-up after acute pulmonary embolism.
Farmakis IT, Valerio L, Barco S, Alsheimer E, Ewert R, Giannakoulas G, Hobohm L, Keller K, Mavromanoli AC, Rosenkranz S, Morris TA, Konstantinides SV, Held M, Dumitrescu D. Farmakis IT, et al. Among authors: konstantinides sv. Eur Respir J. 2023 Jun 8;61(6):2300059. doi: 10.1183/13993003.00059-2023. Print 2023 Jun. Eur Respir J. 2023. PMID: 36958742 Free PMC article.
CONCLUSIONS: Abnormal exercise capacity of cardiopulmonary origin is frequent after PE, being associated with clinical and haemodynamic impairment as well as long-term QoL reduction. CPET can be considered for selected patients with persisting symptoms after acute PE to id …
CONCLUSIONS: Abnormal exercise capacity of cardiopulmonary origin is frequent after PE, being associated with clinical and haemodynamic impa …
Recovery of right ventricular function after intermediate-risk pulmonary embolism: results from the multicentre Pulmonary Embolism International Trial (PEITHO)-2.
Mavromanoli AC, Barco S, Ageno W, Bouvaist H, Brodmann M, Cuccia C, Couturaud F, Dellas C, Dimopoulos K, Duerschmied D, Empen K, Faggiano P, Ferrari E, Galiè N, Galvani M, Ghuysen A, Giannakoulas G, Huisman MV, Jiménez D, Kozak M, Lang IM, Meneveau N, Münzel T, Palazzini M, Petris AO, Piovaccari G, Salvi A, Schellong S, Schmidt KH, Verschuren F, Schmidtmann I, Toenges G, Klok FA, Konstantinides SV; PEITHO-2 Investigators. Mavromanoli AC, et al. Among authors: konstantinides sv. Clin Res Cardiol. 2023 Oct;112(10):1372-1381. doi: 10.1007/s00392-022-02138-4. Epub 2022 Dec 21. Clin Res Cardiol. 2023. PMID: 36539534 Free PMC article. Clinical Trial.
Almost one in four patients, however, continued to have evidence of RV dysfunction over the long term....
Almost one in four patients, however, continued to have evidence of RV dysfunction over the long term....
From acute pulmonary embolism to post-pulmonary embolism sequelae.
Farmakis IT, Keller K, Barco S, Konstantinides SV, Hobohm L. Farmakis IT, et al. Among authors: konstantinides sv. Vasa. 2023 Jan;52(1):29-37. doi: 10.1024/0301-1526/a001042. Epub 2022 Nov 29. Vasa. 2023. PMID: 36444524 Free article. Review.
Then, we will provide a definition of the post-PE syndrome and present the so far accumulated evidence regarding its epidemiology and the implications that arise for further diagnosis and treatment. Lastly, we will explore the most devastating long-term complication of PE, …
Then, we will provide a definition of the post-PE syndrome and present the so far accumulated evidence regarding its epidemiology and the im …
Cost-of-Illness Analysis of Long-Term Health Care Resource Use and Disease Burden in Patients With Pulmonary Embolism: Insights From the PREFER in VTE Registry.
Farmakis IT, Barco S, Mavromanoli AC, Agnelli G, Cohen AT, Giannakoulas G, Mahan CE, Konstantinides SV, Valerio L. Farmakis IT, et al. Among authors: konstantinides sv. J Am Heart Assoc. 2022 Oct 18;11(20):e027514. doi: 10.1161/JAHA.122.027514. Epub 2022 Oct 17. J Am Heart Assoc. 2022. PMID: 36250664 Free PMC article.
We aimed to provide estimates for the economic and disease burden of PE also accounting for long-term health care use and both direct and indirect costs beyond the acute phase. ...
We aimed to provide estimates for the economic and disease burden of PE also accounting for long-term health care use and both direct …
Cardiac and Cerebral Arterial Complications of Lemierre Syndrome: Results from a Systematic Review and Individual Patient Data Meta-analysis.
Pleming W, Barco S, Voci D, Sacco C, Zane F, Granziera S, Corsi G, Konstantinides SV, Kucher N, Pecci A, Valerio L. Pleming W, et al. Among authors: konstantinides sv. Hamostaseologie. 2022 Aug;42(4):261-267. doi: 10.1055/a-1694-8723. Epub 2022 Mar 7. Hamostaseologie. 2022. PMID: 35255510 Free PMC article.
CONCLUSIONS: While Lemierre syndrome is known to be primarily characterized by venous thromboembolic events, our results suggest that local or distant arterial complications may occur in approximately one-tenth of patients and may be associated with a greater risk of long-term …
CONCLUSIONS: While Lemierre syndrome is known to be primarily characterized by venous thromboembolic events, our results suggest that local …
Reduced-Dose Intravenous Thrombolysis for Acute Intermediate-High-risk Pulmonary Embolism: Rationale and Design of the Pulmonary Embolism International THrOmbolysis (PEITHO)-3 trial.
Sanchez O, Charles-Nelson A, Ageno W, Barco S, Binder H, Chatellier G, Duerschmied D, Empen K, Ferreira M, Girard P, Huisman MV, Jiménez D, Katsahian S, Kozak M, Lankeit M, Meneveau N, Pruszczyk P, Petris A, Righini M, Rosenkranz S, Schellong S, Stefanovic B, Verhamme P, de Wit K, Vicaut E, Zirlik A, Konstantinides SV, Meyer G; PEITHO-3 Investigators. Sanchez O, et al. Among authors: konstantinides sv. Thromb Haemost. 2022 May;122(5):857-866. doi: 10.1055/a-1653-4699. Epub 2021 Oct 31. Thromb Haemost. 2022. PMID: 34560806 Free PMC article. Clinical Trial.
The Pulmonary Embolism International THrOmbolysis (PEITHO)-3 study (ClinicalTrials.gov Identifier: NCT04430569) is a randomized, placebo-controlled, double-blind, multicenter, multinational trial with long-term follow-up. We will compare the efficacy and safety of a reduce …
The Pulmonary Embolism International THrOmbolysis (PEITHO)-3 study (ClinicalTrials.gov Identifier: NCT04430569) is a randomized, placebo-con …
28 results