Pancreatic transduction by helper-dependent adenoviral vectors via intraductal delivery.
Morró M, Teichenne J, Jimenez V, Kratzer R, Marletta S, Maggioni L, Mallol C, Ruberte J, Kochanek S, Bosch F, Ayuso E.
Morró M, et al. Among authors: kochanek s.
Hum Gene Ther. 2014 Sep;25(9):824-36. doi: 10.1089/hum.2013.182.
Hum Gene Ther. 2014.
PMID: 25046147
Free PMC article.
Helper-dependent adenoviral vectors (HDAds) are promising tools for gene therapy because of their large cloning capacity, high levels of transgene expression, and long-term persistence in immunocompetent animals. Nevertheless, the ability of HDAds to transduce the pancreas …
Helper-dependent adenoviral vectors (HDAds) are promising tools for gene therapy because of their large cloning capacity, high levels of tra …