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Development of resistance to FGFR inhibition in urothelial carcinoma via multiple pathways in vitro.
Pettitt GA, Hurst CD, Khan Z, McPherson HR, Dunning MC, Alder O, Platt FM, Black EV, Burns JE, Knowles MA. Pettitt GA, et al. Among authors: knowles ma. J Pathol. 2023 Feb;259(2):220-232. doi: 10.1002/path.6034. Epub 2022 Dec 13. J Pathol. 2023. PMID: 36385700 Free PMC article.
To model this, we derived resistant sublines of two FGFR-driven bladder cancer cell lines by long-term culture with the FGFR inhibitor PD173074 and explored mechanisms using expression profiling and whole-exome sequencing. ...
To model this, we derived resistant sublines of two FGFR-driven bladder cancer cell lines by long-term culture with the FGFR inhibito …
Catheter ablation of right atrial ganglionated plexi to treat cardioinhibitory neurocardiogenic syncope: a long-term follow-up prospective study.
Calo L, Rebecchi M, Sette A, Sciarra L, Borrelli A, Scara A, Grieco D, Politano A, Sgueglia M, De Luca L, Martino A, Panattoni G, Golia P, Turrisi OV, Knowles M, Strano S, de Ruvo E. Calo L, et al. Among authors: knowles m. J Interv Card Electrophysiol. 2021 Sep;61(3):499-510. doi: 10.1007/s10840-020-00840-9. Epub 2020 Aug 6. J Interv Card Electrophysiol. 2021. PMID: 32766945
Performance of Viabahn balloon-expandable stent compared with self-expandable covered stents for branched endovascular aortic repair.
Motta F, Parodi FE, Knowles M, Crowner JR, Pascarella L, McGinigle KL, Marston WA, Kibbe MR, Ohana E, Farber MA. Motta F, et al. Among authors: knowles m. J Vasc Surg. 2021 Feb;73(2):410-416.e2. doi: 10.1016/j.jvs.2020.05.028. Epub 2020 May 27. J Vasc Surg. 2021. PMID: 32473341 Free article.
Categorical variables were expressed as total and percentage, and continuous variables were expressed as median (interquartile range). Kaplan-Meier curves were used to estimate long-term results. Groups were compared with the log-rank test. P value <.05 was considered s …
Categorical variables were expressed as total and percentage, and continuous variables were expressed as median (interquartile range). Kapla …
Visceral stent patency after fenestrated endovascular aneurysm repair using bare-metal stent extensions versus covered stents only.
Khoury MK, Timaran DE, Knowles M, Timaran CH. Khoury MK, et al. Among authors: knowles m. J Vasc Surg. 2020 Jan;71(1):23-29. doi: 10.1016/j.jvs.2019.03.054. Epub 2019 Jul 4. J Vasc Surg. 2020. PMID: 31280980 Free article.
CONCLUSIONS: The use of distal uncovered stents to prevent kinks was not associated with decreased early branch patency. The long-term outcomes of bare-metal stents remain to be determined. For now, the use of uncovered stents distal to covered stents may be considered to …
CONCLUSIONS: The use of distal uncovered stents to prevent kinks was not associated with decreased early branch patency. The long-term …
Nasal Nitric Oxide in Primary Immunodeficiency and Primary Ciliary Dyskinesia: Helping to Distinguish Between Clinically Similar Diseases.
Zysman-Colman ZN, Kaspy KR, Alizadehfar R, NyKamp KR, Zariwala MA, Knowles MR, Vinh DC, Shapiro AJ. Zysman-Colman ZN, et al. Among authors: knowles mr. J Clin Immunol. 2019 Feb;39(2):216-224. doi: 10.1007/s10875-019-00613-8. Epub 2019 Mar 26. J Clin Immunol. 2019. PMID: 30911954 Free PMC article.
Participants underwent nNO testing by standardized protocol using a chemiluminescence analyzer and completed a questionnaire concerning their chronic oto-sino-pulmonary symptoms, including key clinical criteria specific to diagnosed PCD (neonatal respiratory distress at term …
Participants underwent nNO testing by standardized protocol using a chemiluminescence analyzer and completed a questionnaire concerning thei …
Oncolytic Immunotherapy for Bladder Cancer Using Coxsackie A21 Virus.
Annels NE, Arif M, Simpson GR, Denyer M, Moller-Levet C, Mansfield D, Butler R, Shafren D, Au G, Knowles M, Harrington K, Vile R, Melcher A, Pandha H. Annels NE, et al. Among authors: knowles m. Mol Ther Oncolytics. 2018 Feb 14;9:1-12. doi: 10.1016/j.omto.2018.02.001. eCollection 2018 Jun 29. Mol Ther Oncolytics. 2018. PMID: 29989024 Free PMC article.
Given the importance of the immunogenicity of dying cancer cells for triggering tumor-specific responses and long-term therapeutic success, the ability of CVA21 to induce immunogenic cell death was investigated. ...
Given the importance of the immunogenicity of dying cancer cells for triggering tumor-specific responses and long-term therapeutic su …
Phase 2 trial of neoadjuvant chemotherapy and transoral endoscopic surgery with risk-adapted adjuvant therapy for squamous cell carcinoma of the head and neck.
Weiss JM, Grilley-Olson JE, Deal AM, Zevallos JP, Chera BS, Paul J, Knowles MF, Usenko D, Weissler MC, Patel S, Hayes DN, Hackman T. Weiss JM, et al. Among authors: knowles mf. Cancer. 2018 Jul 15;124(14):2986-2992. doi: 10.1002/cncr.31526. Epub 2018 May 9. Cancer. 2018. PMID: 29741773 Free article. Clinical Trial.
Neoadjuvant, systemic therapy and surgical resection followed by risk-adapted adjuvant therapy resulted in high response rates and excellent long-term outcomes and should be further studied. Cancer 2018;124:2986-92. 2018 American Cancer Society....
Neoadjuvant, systemic therapy and surgical resection followed by risk-adapted adjuvant therapy resulted in high response rates and excellent …
A Commercially Available Portion-Controlled Diet Program Is More Effective for Weight Loss than a Self-Directed Diet: Results from a Randomized Clinical Trial.
Cook CM, McCormick CN, Knowles M, Kaden VN. Cook CM, et al. Among authors: knowles m. Front Nutr. 2017 Nov 7;4:55. doi: 10.3389/fnut.2017.00055. eCollection 2017. Front Nutr. 2017. PMID: 29164129 Free PMC article.
Additionally, future research is warranted in order to understand the effects of this program, and similar programs, on longer term changes in body weight, in particular weight loss maintenance, as weight regain is common following the cessation of a structured weight loss …
Additionally, future research is warranted in order to understand the effects of this program, and similar programs, on longer term c …
Financing Long-Term Services and Supports: Continuity and Change.
Wiener JM, Knowles ME, White EE. Wiener JM, et al. Among authors: knowles me. Research Triangle Park (NC): RTI Press; 2017 Sep. Research Triangle Park (NC): RTI Press; 2017 Sep. PMID: 32310345 Free Books & Documents. Review.
This article provides an overview of financing for long-term services and supports (LTSS) in the United States, paying special attention to how it has changed and not changed over the last 30 years. ...Medicaid-a means-tested program-continues to dominate LTSS financing, w …
This article provides an overview of financing for long-term services and supports (LTSS) in the United States, paying special attent …
34 results