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The Vitamin D Receptor-BIM Axis Overcomes Cisplatin Resistance in Head and Neck Cancer.
Khamis A, Gül D, Wandrey M, Lu Q, Knauer SK, Reinhardt C, Strieth S, Hagemann J, Stauber RH. Khamis A, et al. Among authors: knauer sk. Cancers (Basel). 2022 Oct 19;14(20):5131. doi: 10.3390/cancers14205131. Cancers (Basel). 2022. PMID: 36291915 Free PMC article.
As inherent and acquired therapy resistance counteracts improvement in long-term survival, novel multi-targeting strategies triggering cancer cell apoptosis are urgently required. ...
As inherent and acquired therapy resistance counteracts improvement in long-term survival, novel multi-targeting strategies triggerin …
A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancer.
Stauber RH, Knauer SK, Habtemichael N, Bier C, Unruhe B, Weisheit S, Spange S, Nonnenmacher F, Fetz V, Ginter T, Reichardt S, Liebmann C, Schneider G, Krämer OH. Stauber RH, et al. Among authors: knauer sk. Oncotarget. 2012 Jan;3(1):31-43. doi: 10.18632/oncotarget.430. Oncotarget. 2012. PMID: 22289787 Free PMC article.
As inherent and acquired resistance to therapy counteracts improvement of long-term survival, novel multi-targeting strategies triggering cancer cell death are urgently required. ...
As inherent and acquired resistance to therapy counteracts improvement of long-term survival, novel multi-targeting strategies trigge …
Nuclear receptors in head and neck cancer: current knowledge and perspectives.
Schweitzer A, Knauer SK, Stauber RH. Schweitzer A, et al. Among authors: knauer sk. Int J Cancer. 2010 Feb 15;126(4):801-9. doi: 10.1002/ijc.24968. Int J Cancer. 2010. PMID: 19839054 Free article. Review.
However, a high rate of early recurrences and metastasis still counteract improvement of long-term survival. Hence, the quest for molecular mechanisms and key regulatory factors exploitable by targeted therapies is still ongoing. ...
However, a high rate of early recurrences and metastasis still counteract improvement of long-term survival. Hence, the quest for mol …
NO signaling confers cytoprotectivity through the survivin network in ovarian carcinomas.
Engels K, Knauer SK, Loibl S, Fetz V, Harter P, Schweitzer A, Fisseler-Eckhoff A, Kommoss F, Hanker L, Nekljudova V, Hermanns I, Kleinert H, Mann W, du Bois A, Stauber RH. Engels K, et al. Among authors: knauer sk. Cancer Res. 2008 Jul 1;68(13):5159-66. doi: 10.1158/0008-5472.CAN-08-0406. Cancer Res. 2008. PMID: 18593915
Despite considerable success in the treatment of epithelial ovarian cancer (EOC), therapy resistance counteracts improvement of long-term survival. The dual role of survivin as an apoptosis inhibitor and mitotic regulator has been associated with disease outcome. ...
Despite considerable success in the treatment of epithelial ovarian cancer (EOC), therapy resistance counteracts improvement of long-term …
Dynamic survivin in head and neck cancer: molecular mechanism and therapeutic potential.
Lippert BM, Knauer SK, Fetz V, Mann W, Stauber RH. Lippert BM, et al. Among authors: knauer sk. Int J Cancer. 2007 Sep 15;121(6):1169-74. doi: 10.1002/ijc.22941. Int J Cancer. 2007. PMID: 17617794 Free article. Review.
Although disease management of head and neck squamous cell carcinomas (HNSCC) has improved significantly, therapy resistance leading to tumor recurrence still counteracts improvement of long-term survival. Consequently, identification of molecular markers that signal incre …
Although disease management of head and neck squamous cell carcinomas (HNSCC) has improved significantly, therapy resistance leading to tumo …