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Improving deep learning-based segmentation of diatoms in gigapixel-sized virtual slides by object-based tile positioning and object integrity constraint.
Kloster M, Burfeid-Castellanos AM, Langenkämper D, Nattkemper TW, Beszteri B. Kloster M, et al. PLoS One. 2023 Feb 24;18(2):e0272103. doi: 10.1371/journal.pone.0272103. eCollection 2023. PLoS One. 2023. PMID: 36827378 Free PMC article.
We tested this hypothesis by comparing a standard sliding window / fixed-stride tiling approach with two new approaches we term object-based tile positioning with and without object integrity constraint. ...
We tested this hypothesis by comparing a standard sliding window / fixed-stride tiling approach with two new approaches we term objec …
Long-term azithromycin use is not associated with QT prolongation in children with cystic fibrosis.
Magaret AS, Salerno J, Deen JF, Kloster M, Mayer-Hamblett N, Ramsey BW, Nichols DP. Magaret AS, et al. Among authors: kloster m. J Cyst Fibros. 2021 Mar;20(2):e16-e18. doi: 10.1016/j.jcf.2020.11.005. Epub 2020 Nov 24. J Cyst Fibros. 2021. PMID: 33246911 Free PMC article.
Among 221 study participants with a median of 18 months follow-up, increased corrected QT interval (QTc) of 30 msec was rare, at 3.4 occurrences per 100 person-years; and incidence of QTc prolongation was no higher in the AZM arm than the placebo arm (1.8 versus 5.4 per 100 perso …
Among 221 study participants with a median of 18 months follow-up, increased corrected QT interval (QTc) of 30 msec was rare, at 3.4 occurre …
Impact of Sustained Eradication of New Pseudomonas aeruginosa Infection on Long-term Outcomes in Cystic Fibrosis.
Mayer-Hamblett N, Kloster M, Rosenfeld M, Gibson RL, Retsch-Bogart GZ, Emerson J, Thompson V, Ramsey BW. Mayer-Hamblett N, et al. Among authors: kloster m. Clin Infect Dis. 2015 Sep 1;61(5):707-15. doi: 10.1093/cid/civ377. Epub 2015 May 13. Clin Infect Dis. 2015. PMID: 25972024 Free PMC article. Clinical Trial.
A key question is whether children with newly acquired Pa infection who are able to achieve sustained eradication after early antipseudomonal therapy demonstrate improved long-term health outcomes compared with those who are unable to achieve a sustained microbiologic resp …
A key question is whether children with newly acquired Pa infection who are able to achieve sustained eradication after early antipseudomona …
Lung function distinguishes preschool children with CF from healthy controls in a multi-center setting.
Kerby GS, Rosenfeld M, Ren CL, Mayer OH, Brumback L, Castile R, Hart MA, Hiatt P, Kloster M, Johnson R, Jones P, Davis SD. Kerby GS, et al. Among authors: kloster m. Pediatr Pulmonol. 2012 Jun;47(6):597-605. doi: 10.1002/ppul.21589. Epub 2011 Nov 11. Pediatr Pulmonol. 2012. PMID: 22081559
RATIONALE: Conducting clinical trials in cystic fibrosis (CF) preschoolers has been limited by lack of sensitive lung function measures performed across sites. OBJECTIVES: (1) Assess feasibility and short-term reproducibility of spirometry, forced oscillometry (FO), and in …
RATIONALE: Conducting clinical trials in cystic fibrosis (CF) preschoolers has been limited by lack of sensitive lung function measures perf …